Gene Information

Name : nrdF (lhv_1900)
Accession : YP_001578044.1
Strain : Lactobacillus helveticus DPC 4571
Genome accession: NC_010080
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 1870500 - 1871522 bp
Length : 1023 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGATAGGAGCAAATATGAGTTATTATGATTATTCACAGTCACCAGTTGAATTTGCTTACAATAACAACGGCAAAAATAT
GCGAGCTATTAACTGGAATGACATTAAAGATGATAAGGATCTTGAGGTTTGGAACAGAGTTACTCAAAACTTTTGGTTAC
CTGAAAAAATCCCAGTTTCGAATGATATAAGTTCTTGGAATCAATTATCTGATGACTGGCAACAGCTTATAACTCGCACT
TTCACTGGATTGACTTTATTAGATACAACTCAAGCAAGTGTGGGTGATGTAGCCCAAATTAAAAATTCACAAACTGATAT
AGAGCAAGCTATCTATGCAAATTTTGCTTTTATGGTTGCTGTCCATGCAAGATCATATGGAACTATTTTTTCTACTTTAT
GTACTAGTGAACAAATTGAAGAAGCGCATGAATGGGTAGTTAATAATGATGCTTTACAAGCAAGAGCGAAAGCGGTAATT
CCGTATTATACAGGCAATGATCCGCTTAAATCAAAGGTTGCCGCAGCAATTATGCCAGGGTTCCTGCTTTATGGTGGTTT
TTATTTACCATTTTATTTAGCTGCAAGAGGTAAATTGCCTAATACTGCTGATATTATTAGATTGATCTTAAGAGATAAGG
TTATTCACAATTATTATAGTGGTTACAAATATCAATTGGCCGTAAAGAAATTAGCTCCAGCTAAACAAGCAGAAATGAAA
AAATTCGTTTTTGATTTCTTAGATAAACTAATTGATTTGGAAAAGAAATATTTGCACGAGCTTTATGGTGATTTTGATTT
GGTTGATGATGCAATTCATTTCAGTTTGTATAATGCAGGTAAATTTTTACAAAATTTAGGCTATGATTCTCCTTTTACCG
CAGAAGAAACTTATATTTCTCCAGAAGTATTCGCTCAATTATCAGCTCAAGCTGATGAAAACCATGATTTCTTTTCTGGT
AATGGTTCTTCATATGTAATGGGAACAGGAGAGGAGACTAAAGATGATGACTGGGATTTCTAA

Protein sequence :
MIGANMSYYDYSQSPVEFAYNNNGKNMRAINWNDIKDDKDLEVWNRVTQNFWLPEKIPVSNDISSWNQLSDDWQQLITRT
FTGLTLLDTTQASVGDVAQIKNSQTDIEQAIYANFAFMVAVHARSYGTIFSTLCTSEQIEEAHEWVVNNDALQARAKAVI
PYYTGNDPLKSKVAAAIMPGFLLYGGFYLPFYLAARGKLPNTADIIRLILRDKVIHNYYSGYKYQLAVKKLAPAKQAEMK
KFVFDFLDKLIDLEKKYLHELYGDFDLVDDAIHFSLYNAGKFLQNLGYDSPFTAEETYISPEVFAQLSAQADENHDFFSG
NGSSYVMGTGEETKDDDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 6e-70 50