Gene Information

Name : leuS (lhv_1726)
Accession : YP_001577906.1
Strain : Lactobacillus helveticus DPC 4571
Genome accession: NC_010080
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1685280 - 1687694 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGTATAACCACAAAGTAGTTGAAAAGAAATGGCAAGATTATTGGGCAAAACATGATACCTTCAAGACAGGTACAGATCC
CAAGAAGAAAAATTATTATGCATTGGACATGTTCCCATTCCCATCTGGTAAGGGACTTCACGTAGGTCACCCAGAAGGAT
ATACTGCAACGGATATTGTCTCACGTATGAAGCGTGCACAAGGCTACAATGTGCTTCACCCAATGGGTTGGGATGCATTT
GGACTTCCAACAGAACAATATGCATTGAAGACCGGTGAAGATCCAGCTGTTGTTACTAAGAACAACATTGCAAACTTTAA
GCGTCAACTTAACAAGTTAGGCTTTTCATACGACTGGGATCGTGAAATTACTACTAGTGATCCTAACTACTACAAGTGGA
CTCAATGGGTCTTTGAACAAATGTACAAAAAGGGTCTTGCTTATGAAGCTGAAGTACCAGTTAACTGGTCACCAGACCTT
GGTACTGTTGTAGCTAACGAAGAAGTTATCGATGGTAAGACTGAACGTGGTGGATACCCAGTTTACCGTCGTAACATGCG
TCAATGGATGCTTAAGATGACTGCTTATGCAGATCGTCTTTTGGAAGACCTTGATGACTTGGACTGGCCAGAACCAGTTA
AGGAAATGCAACGTAACTGGATTGGTCGTTCAGTTGGTGCACAAGTAACTTTCAAGATTAAAGATAGTGACAAGACTTTT
GACATCTTTACCACTCGTCCTGATACCTTATTTGGTTGTTCATACACTGTTCTTGCTCCAGAAAACAAGTTGGTTCAAGA
AATTACCACAGATGGTCATAGAGACGAAGTTAATGCCTACATCAAGAAGATTGAATCTAAGTCTGACCTTGAAAGAACTG
ATTTGAACAAGGATAAGACTGGTGTATTTACTGGTGCTTATGCAATTAACCCAGTTAACGGCAAGGAAGTGCCAATTTGG
ATTTCTGACTACGTTTTAGCAAGCTATGGTACTGGTGCCGTAATGGCAGTTCCAGCTCACGATGATCGTGACTACGCTTT
TGCTAAAAAGTTTGATTTGCCAATTAATCAAGTACTTGAAGGCGGCGATCTTTCTAAGGCTGCCTTCACTGAAGATGGTC
CACACATTAACTCAGAATTCTTGAATGGCTTGAACATCAAGGATGCTAAGAAGAAGATGGTTGACTGGCTTGAAGAACAC
AACTGCGGTGAAAAGAAAGTTAACTACAAGCTTCGCGACTGGGACTTCAGTCGTCAACGTTACTGGGGTGAACCAATTCC
AGTTATCCACTGGGAAGACGGTACTACTTCACTTGTTCCAGAAGATCAACTTCCACTTCGTTTGCCACATGCAACTGATA
TTAAGCCATCAGGTACTCCAGAAAGTCCATTAGCTAACTTGACTGACTGGGTAAATGTAGTTGATGAAATGGGTCGAAAA
GGTAAGCGTGAAACCAACACTATGCCTAACTGGGCTGGTTCAAGCTGGTACTACTTGCGTTACGTTGATCCACACAATGA
TAAAGAATTAGCTGATTACGACTTATTGAAACAATGGCTTCCAGTTGACCTTTACATCGGTGGTGCAGAACACGCAGTTC
GTCACCTTCTTTACGCTAGATTCTGGCACAAGGTTCTTTACGACTTGGGTGTTGTTCCAACCAAGGAACCATTCCAACGT
TTGTACAACCAAGGTTTGATCTTGAAGAACCATGAAAAGATGTCTAAGTCAAAGGGTAACGTAGTTAACCCAGACGAAGT
AATCGATGAATATGGTGCAGACTCACTTAGAATGTACGAAATGTTCATGGGCCCACTTGATGCTTCAATCGACTGGGATG
ACAACGGTCCAGCTTCAACCAAGAAGTTCTTAGACCGTGTATGGCGTTTGTTCGTTAATGACCTTGACTTGAAGGCAATT
CCACAAGAAAGAATTGTGGATAAAAACGATGGTGAACTCGACAAGGTTTACGCAGAAACTGTTAAGAAGGTTACTGAAGA
CTTTGACGCTCTTCACTTCAACACCGCTATTTCTCAAATGATGGTCTTCATCAACGCTGCTCAAAAGGCTAAGACTATTC
CACGGGAATACGTAGAAGGTTTCGTTAAGCTTTTGGCACCAGTTGCTCCACACATGATGGAAGAAATCTGGCAAGTATTT
GGTCATGATGAATCAATTACTTACGCTAAGTGGCCAACTTATGATCCAGCTAAATTAGTTGAATCTACTGTAGAAATCAT
GGTTCAAGTTAACGGTAAGCTTCGTGGCAAGTTCGAAGCTGCTAAGGATGCAGATAGAGATGACGTTCAAAAGCAAGCTA
TGGCTTTACCACACGTACAAAAATTCTTGGAAGGCAAGGACGTTAAGAAAGTTATCGTTGTACCTAACAAGATCGTTAAT
ATTGTTGCTAAATAA

Protein sequence :
MYNHKVVEKKWQDYWAKHDTFKTGTDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVSRMKRAQGYNVLHPMGWDAF
GLPTEQYALKTGEDPAVVTKNNIANFKRQLNKLGFSYDWDREITTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDL
GTVVANEEVIDGKTERGGYPVYRRNMRQWMLKMTAYADRLLEDLDDLDWPEPVKEMQRNWIGRSVGAQVTFKIKDSDKTF
DIFTTRPDTLFGCSYTVLAPENKLVQEITTDGHRDEVNAYIKKIESKSDLERTDLNKDKTGVFTGAYAINPVNGKEVPIW
ISDYVLASYGTGAVMAVPAHDDRDYAFAKKFDLPINQVLEGGDLSKAAFTEDGPHINSEFLNGLNIKDAKKKMVDWLEEH
NCGEKKVNYKLRDWDFSRQRYWGEPIPVIHWEDGTTSLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDEMGRK
GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKQWLPVDLYIGGAEHAVRHLLYARFWHKVLYDLGVVPTKEPFQR
LYNQGLILKNHEKMSKSKGNVVNPDEVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDRVWRLFVNDLDLKAI
PQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINAAQKAKTIPREYVEGFVKLLAPVAPHMMEEIWQVF
GHDESITYAKWPTYDPAKLVESTVEIMVQVNGKLRGKFEAAKDADRDDVQKQAMALPHVQKFLEGKDVKKVIVVPNKIVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 64