Gene Information

Name : set21 (USA300HOU_0428)
Accession : YP_001574334.1
Strain : Staphylococcus aureus TCH1516
Genome accession: NC_010079
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 452147 - 452842 bp
Length : 696 bp
Strand : +
Note : these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :

ATGAAATTAAAAACGTTAGCTAAAGCAACATTAGTATTGGGATTGTTAGCTACTGGTGTAATAACAACAGAAAGTCAAAC
AGTAAAAGCGGCAGAATCAACTCAAGGTCAACACAATTATAAATCGTTAAAATACTACTATAGCAAGCCAAGTATAGAGT
TAAAAAATCTTGATGGTTTGTATAGACAGAAAGTGACAGATAAAGGAGTATATGTTTGGAAGGATCGAAAAGATTATTTT
GTTGGCTTGCTTGGTAAAGATATTGAAAAATACCCTCAAGGTGAGCATGATAAGCAAGATGCATTTTTAGTCATCGAGGA
GGAAACTGTTAATGGAAGACAATATTCAATTGGTGGTTTAAGTAAGACAAATAGTAAAGAATTTAGTAAAGAAGTCGATG
TTAAAGTAACAAGAAAAATTGATGAATCATCGGAAAAGTCTAAAGATAGTAAATTTAAAATTACTAAAGAAGAAATCTCG
TTAAAAGAGTTGGACTTTAAATTAAGAAAAAAATTGATGGAAGAAGAAAAATTATATGGTGCTGTTAATAATAGAAAAGG
TAAAATTGTAGTTAAAATGGAAGATGATAAGTTTTATACTTTCGAACTTACAAAAAAACTACAACCGCATCGCATGGGTG
ACACGATAGATGGTACCAAAATCAAAGAAATTAATGTTGAGCTAGAATATAAATAA

Protein sequence :

MKLKTLAKATLVLGLLATGVITTESQTVKAAESTQGQHNYKSLKYYYSKPSIELKNLDGLYRQKVTDKGVYVWKDRKDYF
VGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEEIS
LKELDFKLRKKLMEEEKLYGAVNNRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
set6nm	YP_001331427.1	superantigen-like protein	Virulence	vSa¥á	Protein	6e-69	100
SAUSA300_0400	YP_493114.1	superantigen-like protein	Virulence	vSa¥á	Protein	6e-69	100
SAS0389	YP_042514.1	superantigen-like protein	Virulence	vSa¥á	Protein	3e-55	82
set21	NP_645204.1	superantigen-like protein	Virulence	vSa¥á	Protein	3e-55	82
SAKOR_00417	YP_008490601.1	Exotoxin	Not tested	vSa¥á	Protein	1e-18	45