Gene Information

Name : secA2 (USA300HOU_2649)
Accession : YP_001576514.1
Strain : Staphylococcus aureus TCH1516
Genome accession: NC_010079
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 2803733 - 2806123 bp
Length : 2391 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGAAACATAAACTAGATGTTACGATAAACGAATTAAGACTAAAGTCGATTAGAAAAATAGTGAAACGCATCAATACATG
GAGCGATGAAGTTAAATCATATTCTGATGATGCGTTAAAACAAAAGACAATAGAATTTAAAGAACGTTTAGCATCAGGAG
TTGATACACTAGATACATTGTTACCTGAAGCTTATGCAGTGGCACGTGAAGCGAGCTGGAGAGTATTAGGTATGTATCCT
AAAGAAGTTCAGTTAATCGGAGCGATTGTATTGCATGAAGGTAACATTGCGGAGATGCAAACAGGCGAAGGTAAAACATT
AACGGCAACGATGCCTTTATATTTAAATGCTCTTTCGGGAAAAGGAACATATTTAATTACAACGAATGATTATTTAGCGA
AGCGAGATTTTGAAGAGATGCAACCATTATATGAATGGTTAGGTTTAACTGCTTCATTAGGTTTTGTTGATATTGTGGAT
TATGAGTATCAAAAAGGGGAAAAACGTAATATATATGAACATGATATTATATATACAACTAATGGACGTCTCGGTTTTGA
TTATTTAATTGATAATTTGGCTGATAGTGCGGAAGGGAAATTTTTACCACAATTAAATTACGGTATTATTGATGAAGTGG
ATTCAATCATTTTAGATGCTGCTCAAACACCATTAGTTATTTCGGGTGCACCAAGATTACAATCAAATCTATTTCATATT
GTGAAAGAGTTTGTAGATACATTGATTGAAGACGTGCATTTTAAAATGAAGAAGACCAAAAAAGAAATATGGCTGTTAAA
TCAAGGTATTGAAGCGGCACAATCATACTTTAATGTTGAAGATTTATATAGCGAACAAGCGATGGTCCTAGTGCGTAATA
TTAATTTAGCACTGCGCGCACAATATTTGTTTGAATCTAATGTCGATTACTTTGTATATAATGGTGATATTGTTTTAATT
GACCGTATTACAGGTCGTATGTTACCGGGAACTAAGTTGCAAGCTGGACTTCACCAAGCTATTGAAGCGAAAGAAGGTAT
GGAGGTTTCAACAGATAAAAGTGTTATGGCAACAATTACCTTCCAGAATTTATTTAAACTTTTTGAATCATTTTCAGGTA
TGACAGCTACAGGAAAATTAGGCGAATCAGAGTTCTTTGATTTGTATTCAAAAATAGTCGTACAAGTACCAACTGATAAA
GCGATTCAACGTATCGATGAACCAGATAAAGTGTTTCGTTCAGTTGATGAGAAAAACATCGCGATGATTCATGATATAGT
TGAACTTCATGAAACGGGGCGACCGGTTTTACTCATAACGAGAACTGCTGAAGCGGCTGAATACTTTTCGAAAGTATTAT
TCCAAATGGATATTCCTAATAATTTACTCATTGCGCAAAATGTTGCAAAAGAAGCGCAGATGATAGCTGAAGCAGGGCAA
ATTGGTTCCATGACTGTTGCGACTAGTATGGCAGGTCGAGGCACAGATATTAAACTTGGTGAAGGTGTCGAAGCATTAGG
TGGATTAGCTGTTATTATTCATGAACATATGGAAAATAGCCGTGTAGACAGGCAATTACGTGGTCGTTCTGGTAGACAAG
GGGATCCGGGATCATCTTGTATATATATTTCACTAGATGATTATTTAGTTAAGCGATGGAGCGATAGTAATTTAGCGGAA
AATAATCAATTATATTCATTAGATGCACAACGATTATCGCAAAGTAATTTGTTTAATCGCAAAGTTAAGCAAATTGTAGT
TAAAGCGCAGCGTATCTCGGAAGAACAAGGGGTTAAAGCTCGTGAAATGGCTAATGAATTTGAAAAAAGCATTAGTATAC
AGCGAGATCTTGTATACGAGGAACGCAATCGAGTTTTAGAAATAGATGATGCTGAGAATCAAGATTTTAAAGCGTTAGCT
AAAGATGTATTTGAAATGTTTGTAAATGAGGAAAAGGTGCTAACAAAATCGCGTGTTGTCGAGTATATTTATCAAAATTT
AAGTTTCCAATTTAATAAAGATGTGGCTTGTGTTAATTTTAAAGATAAGCAAGCAGTAGTGACATTTTTATTAGAGCAAT
TTGAAAAGCAATTAGCTTTGAATCGTAAAAACATGCAAAGTGCATATTATTATAATATTTTCGTTCAAAAAGTCTTTTTG
AAAGCAATTGATTCATGTTGGTTAGAACAAGTCGACTATTTACAACAATTAAAAGCAAGCGTTAATCAACGACAAAATGG
GCAACGTAACGCTATTTTTGAATACCATAGAGTTGCCTTAGATTCATTTGAAGTTATGACACGAAATATCAAAAAAAGAA
TGGTGAAAAATATTTGTCAAAGCATGATTACATTTGATAAAGAGGGTATGCCAGTTATACATTTTCCATAA

Protein sequence :
MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYP
KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD
YEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI
VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI
DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDK
AIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQ
IGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAE
NNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALA
KDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFL
KAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-155 46