Gene Information

Name : hysA (USA300HOU_2197)
Accession : YP_001576069.1
Strain : Staphylococcus aureus TCH1516
Genome accession: NC_010079
Putative virulence/resistance : Virulence
Product : hyaluronate lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2338236 - 2340665 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGTCAATGACATATAGAATAAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCTGGTGTGATTACTTTGAA
TGGTGGTGAATTCAGAAGTGTTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAGATTATGAAAAAT
TGAGGAACACATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAATAATCCAGATATGAAGAAGAAGTTTGAT
GCTACAGAGAAAGAGGCGACGAATTTACTCAAGGAAATGAAAACTGAAAGTGGTAGGAAATACTTGTGGTCAGGAGCGGA
AACCCTTGAAACTAATTCTTCTCATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAGGAATCCTA
AAACCACTTTAAATACTGACGAAAATAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAA
GAACCAGATAAAAAAGTAAAAGAATTAAGTGAGAATTTTACTAAAACAACTGGCAAGAATACCAACTTAAATTGGTGGGA
TTATGAAATTGGAACACCTAAATCATTAACAAATACGCTTATATTGCTGAATGATCAATTTTCAAATGAAGAAAAGAAAA
AATTCACTGCCCCTATTAAAACTTTCGCCCCAGATAGTGACAAAATATTATCTTCTGTAGGAAAAGCTGAACTTGCTAAA
GGCGGAAATCTAGTAGACATTTCTAAGGTGAAACTTTTAGAATGTATTATCGAAGAAGATAAAGATATGATGAAAAAGTC
TATAGATTCATTTAATAAAGTCTTCACTTACGTTCAAGATTCTGCCACTGGTAAAGAACGTAATGGATTTTATAAAGATG
GCTCTTACATTGATCATCAAGACGTTCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATG
CCGATGATAAAAGAAACACCTTTTAATGATAAAACCCAAAATGATACAACCTTAAAGTCATGGATTGACGACGGATTTAT
GCCACTCATTTATAAAGGTGAAATGATGGATTTATCACGAGGTAGAGCTATCAGTCGTGAAAATGAAACCAGTCACTCAG
CATCTGCAACAGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGATTCAACAAAAGCTAAGTATAAAAAGATT
GTCAAATCTTCAGTAGAGTCAGATTCAAGTTATAAACAAAATGATTATTTAAATTCATATTCGGACATAGATAAAATGAA
GTCTTTAATGACAGATAACAGTATTTCTAAAAACGGATTAACACAACAACTTAAAATATATAATGACATGGATCGTGTCA
CCTATCATAACAAAGACTTAGACTTTGCATTTGGTTTAAGTATGACGTCGAAAAACGTAGCACGCTATGAAAGTATCAAC
GGAGAGAATTTAAAAGGTTGGCACACTGGTGCTGGAATGTCTTATTTATATAACAGCGATGTCAAACACTATCATGATAA
CTTCTGGGTGACAGCCGATATGAAACGTTTATCAGGTACAACAACTTTAGACAATGAAATATTAAAAGATACGGATGATA
AAAAGTCGAGTAAAACTTTTGTTGGCGGAACAAAAGTTGATGACCAACATGCTAGTATCGGAATGGATTTTGAAAATCAG
GACAAAACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAAGTAC
TGATTCATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGAATGGGTATACGTTATATACAGACGATAAACAAA
CAACCAATTCTGATAATCAGGAAAACAATTCAGTCTTTTTAGAGTCCACAGATACCAAAAAGAACATCGGTTATCATTTT
TTAAACAAACCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAAAGAAATAAATAAAAGTCAAAAGGATAC
ACAAAAAACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATTCTGACAATAAATATGGATATGTGTTGTATCCAG
GCTTATCTAAAGATGTCTTTAAGACAAAAAAAGATGAAGTAACTGTCGTTAAGCAAGAAGATGACTTCCACGTTGTGAAA
GATAATGAATCGGTTTGGGCTGGTGTTAATTATAGTAATAGCACTCAAACTTTTGACATTAACAACACTAAAGTCGAAGT
TAAAGCCAAAGGTATGTTTATACTTAAAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCTGAATCTACAA
ATTCCGCTTCAGATATTGAATCTAAAATTTCAATGACCGGTTACTCTATTACAAACAAAAATACGTCGACTTCTAATGAA
TCCGGCGTGCACTTTGAATTAACTAAATAA

Protein sequence :
MSMTYRIKKWQKLSTITLLMAGVITLNGGEFRSVDKHQIAVADTNVQTPDYEKLRNTWLDVNYGYDKYDENNPDMKKKFD
ATEKEATNLLKEMKTESGRKYLWSGAETLETNSSHMTRTYRNIEKIAEAMRNPKTTLNTDENKKKVKDALEWLHKNAYGK
EPDKKVKELSENFTKTTGKNTNLNWWDYEIGTPKSLTNTLILLNDQFSNEEKKKFTAPIKTFAPDSDKILSSVGKAELAK
GGNLVDISKVKLLECIIEEDKDMMKKSIDSFNKVFTYVQDSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMM
PMIKETPFNDKTQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDDSTKAKYKKI
VKSSVESDSSYKQNDYLNSYSDIDKMKSLMTDNSISKNGLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESIN
GENLKGWHTGAGMSYLYNSDVKHYHDNFWVTADMKRLSGTTTLDNEILKDTDDKKSSKTFVGGTKVDDQHASIGMDFENQ
DKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANGYTLYTDDKQTTNSDNQENNSVFLESTDTKKNIGYHF
LNKPKITVKKESHTGKWKEINKSQKDTQKTDEYYEVTQKHSNSDNKYGYVLYPGLSKDVFKTKKDEVTVVKQEDDFHVVK
DNESVWAGVNYSNSTQTFDINNTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSASDIESKISMTGYSITNKNTSTSNE
SGVHFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA YP_001576069.1 hyaluronate lyase VFG1315 Protein 0.0 88