Gene Information

Name : hemC (USA300HOU_1662)
Accession : YP_001575548.1
Strain : Staphylococcus aureus TCH1516
Genome accession: NC_010079
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1771149 - 1772075 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGTAAATTAGTCGTTGGCTCCAGAAGAAGTAAATTAGCTTTAACACAAAGCCAGCAATTTATTGATAAATTAAAAGC
TGTCGAGCCAAATCTAGAAATTGAAATTAAAGAAATTGTCACGAAAGGCGATCGTATAGTAGATAAACAATTGTCTAAAG
TCGGAGGCAAAGGCTTATTTGTTAAAGAAATACAACATGAACTTTTTGAAAAAAATATCGATATGGCAATACACTCGCTT
AAAGACGTACCAAGTGTAATTCCGGAAGGTTTAACATTAGGTTGTATCCCTGATAGAGAATTACCTTTTGATGCGTATAT
TTCTAAAACACATACACCACTATCCCAATTGCCAGAAGGCAGTATTATTGGTACTAGTTCATTACGTCGTGGTGCACAAA
TATTATCTAAGTATCCTAATTTAGAGATTAAATGGATTAGAGGTAATATAGATACACGATTAGAAAAGTTACAAACTGAA
GATTATGATGCGATTATTTTAGCTGCAGCTGGTTTAAGAAGAATGGGCTGGTCAGATGATATTGTAACATCTTATCTTGA
TAGAGATACATTGTTACCTGCAATCGGACAAGGTGCTTTAGGGATAGAATGTCGTAGTGACGATGAAGAACTATTAACAT
TATTAAGCAAAGTACATAATGATGAGGTTGCAAAATGTGTGACTGCTGAACGAACGTTTTTAGCAGAAATGGATGGTAGT
TGTCAGGTGCCAATTGCAGGATATGCTACAATCTCAGATCAAAACGAAATCGAATTTACAGGTTTAATTATGACCCCAGA
TGGTAAAGAACGATTTGAATATACAATGAACGGAACAGATCCGGTTGAGTTAGGCAAAACAGTGAGTAACAAATTAAAAG
AGCAAGGTGCTTATGAAATTATAAAACGCTTAAATGAACAACATTAA

Protein sequence :
MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSL
KDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTE
DYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGS
CQVPIAGYATISDQNEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-63 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-63 47