Gene Information

Name : SARI_00086 (SARI_00086)
Accession : YP_001569181.1
Strain : Salmonella enterica RSK2980
Genome accession: NC_010067
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaS
Function : -
COG functional category : N : Cell motility
COG ID : COG1377
EC number : -
Position : 82385 - 83455 bp
Length : 1071 bp
Strand : +
Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins

DNA sequence :
ATGTCCTCGAATAAAACAGAAAAACCTACTAAAAAACGGCTGGAAGATTCCGCTAAAAAGGGTCAGTCATTTAAAAGTAA
AGATCTTATTATCGCCTGTTTGACTCTGGGAGGAATTGCTTATCTGGTGTCGTATGGCTCATTTAATGAGTTTATGGGAA
TTATTAAGATCATCATTGCAGAAAATTTTGAGCAGAGCATGGCTGACTACAGTCTGGCCGTTTTAGGGGTAGGGTTAAAA
TACCTGATTCCATTTATGCTACTCTGCTTAGTGTGTTCCGCATTACCGACGTTATTACAGACGGGTTTTGTGCTGGCGAC
AGAGGCATTAAAACTTAATTTGTCGGCATTAAACCCGGTCGAAGGGGCGAAAAAACTTTTCAGTATGCGAACAGTAAAAG
ATACGGTCAAAACTTTACTGTATCTCTCATCCTTTGTGGTGGCCGCAATAATTTGCTGGAAAAAATATAAGGTTGAAATC
TTTTCTCAGTTAAATGGCAATGTTATGGGAATTGCCGTCATTTGGCGTGAGCTTCTTCTCGCGTTGGTATTAACTTGCCT
TGCCTGTGCATTAATTGTTTTATTATTGGATGCTATCGCTGAATACTTCCTGACCATGAAAGATATGAAAATGGATAAAG
AAGAAGTGAAGCGTGAGATGAAGGAGCAGGAAGGGAACCCGGAGGTTAAATCTAAAAGACGTGAAGTTCATATGGAAATT
CTGTCTGAACAGGTGAAATCTGATATTGAAAACTCACGTTTGATTGTTGCCAACCCAACGCATATTACGATCGGTATTTA
TTTTAAACCTGAACTGATGCCGTTTCCGATGATCTCAGTGTATGAAACTAATCAGCGCGCACTGGCCGTTCGCTCCTATG
CGGAGAAGGTTGGCGTACCTGTTATCGTCGATATCAAACTGGCGCGCAGTCTTTTCAAAACCCATCGCCGTTATGATTTG
GTGAGTCTGGAAGAAATTGATGAAGTTTTACGTCTTCTGGTTTGGCTGGAAGAGGTAGAAAACGCGGGCAAAGATGTTAT
TCAGCCACAAGAAAACGAGGTACGGCATTGA

Protein sequence :
MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFNEFMGIIKIIIAENFEQSMADYSLAVLGVGLK
YLIPFMLLCLVCSALPTLLQTGFVLATEALKLNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEI
FSQLNGNVMGIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKREMKEQEGNPEVKSKRREVHMEI
LSEQVKSDIENSRLIVANPTHITIGIYFKPELMPFPMISVYETNQRALAVRSYAEKVGVPVIVDIKLARSLFKTHRRYDL
VSLEEIDEVLRLLVWLEEVENAGKDVIQPQENEVRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaS YP_217806.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 6e-129 97
spaS NP_457281.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 5e-130 97
spaS NP_806490.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 5e-130 97
spaS NP_461808.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 3e-130 97
spaS AAS66868.1 SpaS Not tested SSR-2 Protein 3e-68 56
ECs3721 NP_311748.1 surface presentation of antigens protein SpaS Not tested LIM Protein 9e-60 53
ysaU AAS66849.1 YsaU Not tested SSR-1 Protein 2e-44 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SARI_00086 YP_001569181.1 surface presentation of antigens protein SpaS VFG0548 Protein 1e-130 97
SARI_00086 YP_001569181.1 surface presentation of antigens protein SpaS VFG1015 Protein 1e-52 50
SARI_00086 YP_001569181.1 surface presentation of antigens protein SpaS VFG2452 Protein 7e-49 45