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Name : lysS (SARI_04610) Accession : YP_001573524.1 Strain : Salmonella enterica RSK2980 Genome accession: NC_010067 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 4514642 - 4516159 bp Length : 1518 bp Strand : + Note : 'class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRN DNA sequence : ATGTCTGAACAAAACGCACAGGGCGCTGACGAGGTAGTCGATCTTAACAATGAAATGAAGGCACGTCGCGAGAAGCTGGC TGCGCTGCGTGAGCAGGGTATCCCGTTCCCGAACGATTTCCGTCGTGACCGTACCTCAGACCAACTGCACGCAGAGTTTG ACGCGAAAGAAGCTGAAGAACTGGAAGCGCTGAACATTGAAGTGTCTGTCGCGGGCCGTATGATGACTCGCCGTATTATG GGTAAAGCCTCTTTTGTTACCCTGCAAGACGTAGGCGGCCGCATCCAACTGTATGTGGCGCGCGATGATCTGCCGGAAGG CGTTTACAACGAGCAGTTCAAGAAGTGGGATCTTGGCGATATCCTCGGCGCAAAAGGTAAGCTGTTCAAAACCAAAACCG GCGAGCTGTCTATCCACTGCTCGGAACTGCGCCTGCTGACTAAAGCGCTGCGTCCGTTGCCGGATAAATTCCACGGCCTG CAGGACCAGGAAGCGCGCTATCGCCAGCGTTATCTGGATCTCATCTCTAACGATGAATCCCGTAACACGTTCAAAACCCG TTCGAAGATCCTGGCCGGCATTCGCCAGTTCATGGTTGCTCGCGGCTTTATGGAAGTCGAAACCCCGATGATGCAAGTGA TCCCTGGCGGTGCGTCAGCGCGCCCGTTTATCACCCATCACAACGCGTTGGATCTGGACATGTACCTGCGTATCGCGCCG GAACTGTATCTCAAGCGTCTGGTGGTTGGCGGTTTCGAACGCGTGTTCGAAATCAACCGTAACTTCCGTAACGAAGGCAT CTCCGTGCGCCACAACCCTGAGTTCACCATGATGGAACTCTACATGGCGTATGCGGACTACAAAGACCTGATCGAGCTGA CTGAGTCTCTGTTCCGCACGCTGGCGCAGGACGTTCTGGGTAATACCCAGGTTCCATACGGCGATGAAGTGTTTGACTTC GGCAAGCCGTTCGAAAAACTGACCATGCGTGAAGCGATCAAGAAATACCGTCCGGAAACGGATATGGCTGATCTGGACAA CTTCGATTCCGCGAAGGCGATTGCGGAAAGCATCGGCATTCACGTCGAGAAGAGCTGGGGACTGGGCCGTATCGTCACCG AGATCTTTGATGAAGTCGCTGAAGCGCATCTGATTCAGCCGACCTTCATCACCGAATATCCGGCTGAAGTGTCTCCGCTG GCGCGTCGTAATGATGTGAACCCGGAAATCACTGACCGCTTCGAGTTCTTTATCGGCGGTCGTGAAATCGGTAATGGCTT TAGCGAGTTGAACGACGCGGAAGATCAGGCGCAGCGTTTCCAGGATCAGGTTAATGCGAAAGCCGCAGGCGATGACGAAG CTATGTTCTACGACGAAGACTACGTGACGGCGCTGGAACACGGTCTGCCGCCGACAGCAGGTCTGGGTATTGGTATCGAC CGTATGGTGATGCTGTTTACTAACAGCCACACGATTCGCGATGTTATTCTGTTCCCGGCGATGCGTCCGGTGAAATAA Protein sequence : MSEQNAQGADEVVDLNNEMKARREKLAALREQGIPFPNDFRRDRTSDQLHAEFDAKEAEELEALNIEVSVAGRMMTRRIM GKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGL QDQEARYRQRYLDLISNDESRNTFKTRSKILAGIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDVLGNTQVPYGDEVFDF GKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPL ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFQDQVNAKAAGDDEAMFYDEDYVTALEHGLPPTAGLGIGID RMVMLFTNSHTIRDVILFPAMRPVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 1e-170 | 69 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 6e-93 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_001573524.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 6e-171 | 69 |
