Gene Information

Name : tpx (SARI_01299)
Accession : YP_001570343.1
Strain : Salmonella enterica RSK2980
Genome accession: NC_010067
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 1256780 - 1257286 bp
Length : 507 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGTCACAGACTGTACATTTCCAGGGTAACCCGGTCACTGTTGCCAACGTTATTCCGCAGGCTGGCAACAAAGCACAGGC
TTTTACTCTTGTCGCAAAAGATCTGTCTGACGTTTCACTCAGTCAATATGCAGGCAAACGCAAAGTGCTGAATATTTTCC
CAAGCATTGATACTGGCGTATGCGCGGCATCAGTCCGTAAGTTTAACCAACTGGCCACAGAAGTGGAGAATACTGTCGTA
TTGTGCGTTTCTGCTGACCTGCCTTTTGCTCAATCGCGTTTTTGCGGCGCGGAAGGCCTGAGTAATGTTATTACGCTTTC
CACTCTGCGTAATAACGAGTTTCTGAAAAACTACGGCGTCGAAATCACTGACGGCCCGCTGAAAGGCCTGGCGGCGCGCG
CCGTCATCGTGCTTGACGAAAACGACAATGTTATTTTCAGCCAACTGGTGGATGAAATTACCCACGAACCGGACTATGCC
GCCGCGCTGGACGTCCTGAAGGCATAA

Protein sequence : 
MSQTVHFQGNPVTVANVIPQAGNKAQAFTLVAKDLSDVSLSQYAGKRKVLNIFPSIDTGVCAASVRKFNQLATEVENTVV
LCVSADLPFAQSRFCGAEGLSNVITLSTLRNNEFLKNYGVEITDGPLKGLAARAVIVLDENDNVIFSQLVDEITHEPDYA
AALDVLKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 3e-34 48
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 1e-34 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-34 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-34 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001570343.1 thiol peroxidase VFG0087 Protein 4e-35 48