Gene Information

Name : guaA (Pmob_0046)
Accession : YP_001567118.1
Strain : Petrotoga mobilis SJ95
Genome accession: NC_010003
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 40758 - 42281 bp
Length : 1524 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAAAGATTCTTGTTATCGATTATGGTTCTCAGTACACTCAGCTTTTAGCAAAAAGGATTAGGGATCTGGGGGTATT
TTCAGAAGTAATTCAGTATGACGATAATATATCCCTTAGCAATGTGAAAGGCATAATCTTATCCGGTGGACCTGACAGTG
TTTATAATATCGATGCACCCGATATATCAGATGAAATTTTGAACGCTGAACTACCTATTTTAGGTATTTGTTATGGAATG
CAACTTATAGCGAAGAAACTTGGCGGGAAGGTTGAACAAAGAGGTATAGCTGAGTATGGAAAAACGAAGATTAACATAAC
CGATCAATCCCTCTTGTTTAAAAAGATTCCCAGTACGTTTAACGTTTGGATGAGCCACAAGGATATGGTAACTAAAGTTC
CTGAGAAATTTAAAATTACTTCTCTCACCTCAAACAATATCATCTCTTCTTTTGAAAACGAATCAGAAAATATATACTGC
ATCCAATTTCACCCCGAAGTTAGACATACTGAATTCGGAATTGATATATTGAAAAATTTCATTCAGGGTATATGTGGTTT
GAAAGGTTCTTGGACCTTGATGGATTTTGTTGAAAATAAGATAAAAGAAATAAAAGATACAATAGGTGATAAAAAGGCAA
TTATAGCTTTATCAGGTGGAGTAGATTCATCGGTTGCCGCTGTACTAACCCACAGGGCTATTGGCAACAACCTGAAAGCT
ATCTTTGTAAACCATGGTTTTTTGAGAATGAACGAAGTTGAAGAAGTTGAAAGCACGTTCAGAGATTATATGGGTTTGAA
TTTGACAACAGTAGACGCCCAGGAGCGATTTTTAAGCAAATTAAAAGGGGTCACCGATCCCGAACAAAAACGTAAGATCA
TAGGGGAAGAGTTTATAAGGGTTTTTGAGCAAGAAGCAAAAAAAGAAGAAGGTTGCGAGTATTTAATACAGGGAACAATA
TATTCAGATGTCATAGAAAGTGCAAAATCCGGGAAAAAGACATTCAAGATAAAGAGCCATCACAACGTGGGAGGGCTTCC
AGAGGATATAGATTTAAAAATAGTGGAACCACTTAAAGAACTTTTCAAAGACGAAGTTAGAAGCGTTGGAGAAATCTTAG
GTCTCCCAAGAGAGATACTGTACAGGCATCCATTTCCAGGACCGGGATTGGCGATTCGAATCATGGGAGAAATAAACGAT
GAAAAACTCACCATTTTAAAAAAGGTAGACAATATTTTTATAAACACCCTTAAAGAAACAGGCTGGTACGATAAAGTATG
GCAGGCTTTCGCTGTTTTAATACCGGTAAAAACGGTTGGTATAACTGGGGATAAAAGAAGTTATGGCTATGTGGCAGCTT
TAAGATCCGTTGATAGTGTGGAAGGAATGACTGCAGATTGGTCTAAGGTTCCCTTTGAAATTTTGGACTTAGTTTCCAGC
AGAATAACCAACGAAGTTGAAGAAATTACAAGAGTGGTTTACGATATTTCATCAAAACCCCCTGCTACAATAGAATGGGA
ATAA

Protein sequence :
MEKILVIDYGSQYTQLLAKRIRDLGVFSEVIQYDDNISLSNVKGIILSGGPDSVYNIDAPDISDEILNAELPILGICYGM
QLIAKKLGGKVEQRGIAEYGKTKINITDQSLLFKKIPSTFNVWMSHKDMVTKVPEKFKITSLTSNNIISSFENESENIYC
IQFHPEVRHTEFGIDILKNFIQGICGLKGSWTLMDFVENKIKEIKDTIGDKKAIIALSGGVDSSVAAVLTHRAIGNNLKA
IFVNHGFLRMNEVEEVESTFRDYMGLNLTTVDAQERFLSKLKGVTDPEQKRKIIGEEFIRVFEQEAKKEEGCEYLIQGTI
YSDVIESAKSGKKTFKIKSHHNVGGLPEDIDLKIVEPLKELFKDEVRSVGEILGLPREILYRHPFPGPGLAIRIMGEIND
EKLTILKKVDNIFINTLKETGWYDKVWQAFAVLIPVKTVGITGDKRSYGYVAALRSVDSVEGMTADWSKVPFEILDLVSS
RITNEVEEITRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-126 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-126 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-126 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-116 46