Gene Information

Name : lysS (Pmob_0159)
Accession : YP_001567229.1
Strain : Petrotoga mobilis SJ95
Genome accession: NC_010003
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 159783 - 161291 bp
Length : 1509 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGACCTTAGAAATATACGAATGCATCAATTAAAAGAAATGAGGGAAAAAGGATACAATCCGTATAAGTACAATTTTCA
AAAAAATTATACTTCCCAACAAATCAAAGACCTTTTCGATAGTAAAATAGAGGCTGGCCAACAATTACCGGATGAAGTTT
TTAATTTCGGCGGAAGGCTGATGAATTTAAGAAAACATGGCAAATCTGCTTTTGCTGATTTAAAAGATGAATTTGGACGT
ATCCAGGTATATATCCGTTTGGATCAAGTAGGGCAAGAAAACTATGATTTTTTCAAAGAATATATTGATATTGGAGACTG
GATAGGAATAAAAGGTTATCCCTTCAAAACGAGAACTGGCGAATTAACTCTTTTGGCTTTAGATATAGAATTACTCTCAA
AAGCTATTCGCCCTCTTCCTGAAAAATGGCATGGCCTTAAAGATAAAGAAGTTCGATATAGACAAAGATATGTGGATATG
ATCGCAAACGATGACACCATTAAAACCCTCAGAACACGTTTTTTAATCATAAAATACATCAGAGAGTATTTAAACAACAA
AGGTTTTTTAGAAGTTGAAACCCCAGTTCTTCAAAGTATAATGGGTGGAGCAAATGCAAGACCTTTTATTACCCATCTAA
ACGTATATGATATAGATATGTACTTACGCATAGCCACGGAATTACATCTAAAAAGACTAGTCGTAGGTGGGATGGAGAAA
GTTTATGAAATAGGGAAAATATTCAGAAACGAAGGTGTTTCAAACAAACATAATCCTGAATTCACATCTATTGAATTGTA
CCAAGCTTTCGCTGACTACAACGATATGATGGAACTAACCGAAGATCTCTTATACAACATTACCAAAAAAGTTCACAACA
AAGCAAAGATTATGTACCAAGGAGAAGAAATAGATTTCACACCTCCTTTCAAAAGAATAAAGATGAGAGAATTCATACAA
GAAAATCTTGGAATAGATATAGTGGAAGCTAGTGATCAGGAACTGAAAGAGTTTTTGAAAAACAAGGGTGAAGAGGTAGA
AATAGAAGACAGATACCATTACCTCGACAAAGTATGGGATTTAGTCGAAGATAAGATCGTTCAACCTACTTTTGTTATGG
ATTATCCTATCGAATTATCTCCACTGGCAAAAAGAAAAAAAGATGATCCAAGGTTAACCGAAAGGTTTGAATTAATAATA
AAGGGCAATGAAATAGCGAACGCCTTTTCTGAATTGAACGATCCTCAAGACCAATTTGAAAGGTTTAAAAAGCAAATGGA
ACTGAAAGAGTTGGGCGATGAAGAAGCTCAAATGATGGATCTTGATTTCATTAGGGCATTAGAATATGGTTTGCCTCCAA
CTGGAGGACTAGGAATAGGTATTGACAGGGTTTGTATGCTGCTTACTGATACTCCAACTATTCGCGACATTATACCTTTT
CCAATTGTAAAACCCATGGCTTTCGAAGACGAAGAAGCCATGTTAAAAGAAGAAGAGACAAACGAATGA

Protein sequence :
MDLRNIRMHQLKEMREKGYNPYKYNFQKNYTSQQIKDLFDSKIEAGQQLPDEVFNFGGRLMNLRKHGKSAFADLKDEFGR
IQVYIRLDQVGQENYDFFKEYIDIGDWIGIKGYPFKTRTGELTLLALDIELLSKAIRPLPEKWHGLKDKEVRYRQRYVDM
IANDDTIKTLRTRFLIIKYIREYLNNKGFLEVETPVLQSIMGGANARPFITHLNVYDIDMYLRIATELHLKRLVVGGMEK
VYEIGKIFRNEGVSNKHNPEFTSIELYQAFADYNDMMELTEDLLYNITKKVHNKAKIMYQGEEIDFTPPFKRIKMREFIQ
ENLGIDIVEASDQELKEFLKNKGEEVEIEDRYHYLDKVWDLVEDKIVQPTFVMDYPIELSPLAKRKKDDPRLTERFELII
KGNEIANAFSELNDPQDQFERFKKQMELKELGDEEAQMMDLDFIRALEYGLPPTGGLGIGIDRVCMLLTDTPTIRDIIPF
PIVKPMAFEDEEAMLKEEETNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-83 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001567229.1 lysyl-tRNA synthetase VFG1668 Protein 1e-83 46