Gene Information

Name : guaA (Daci_3013)
Accession : YP_001564036.1
Strain : Delftia acidovorans SPH-1
Genome accession: NC_010002
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3315780 - 3317402 bp
Length : 1623 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCATGCAACACGACAAGATCCTCATTCTTGACTTCGGCTCCCAAGTCACCCAGCTGATCGCCCGCCGCGTGCGCGA
AGCCCATGTCTACTGCGAAGTCCACCCCTGCGACGTCAGCAGCGACTGGGTGCGCGAATTCGCCGCCGACGGTCGCCTCA
AGGGCGTGATCCTGTCGGGCAGCCACGCCAGCGTCTATGAAGTGGACGACCGCGCCCCCGACGCCGTGTTCGAGCTGGGC
ATTCCCGTGCTGGGCATCTGCTACGGCATGCAGGCCATGGCCACCCAGCTGGGCGGCAAGGTCGAAGGCTCGCACACCCG
CGAATTCGGCTACGCCGAAGTGCGCGCCCATGGCCACACCGAACTGCTCAAGGGCATCCAGGACTTCGCCACGGCCGAAG
GCCACGGCATGCTCAAGGTCTGGATGAGCCACGGCGACAAGGTCACCGAGCTGCCCCCGGGCTTCAAGGTCATGGCCTCC
ACGCCGTCCTGCCCCATCGCCGGCATGGCCGACGAGGCGCGCCGCTTCTACGCGGTCCAGTTCCACCCCGAAGTCACGCA
CACCGTGCAGGGCGCGGCCCTGCTAAACCGCTTCGTGCGCGAGATCTGTGCGGCCAACGCCGACTGGATCATGGGCGACT
ACATCGAGGAAGCCGTCGCCAAGATCCGCGAGCAGGTGGGTGACGAGGAAGTCATCCTCGGCCTGTCGGGCGGCGTGGAT
TCGTCCGTGGCCGCGGCCCTGATCCACCGCGCCATCGGCGACCAGCTGACCTGCGTCTTCGTGGACCACGGCCTGCTGCG
CCTGAACGAAGGCGACATGGTCATGGAAATGTTCGAGGGCAAGCTGCACGCCAAGGTCATCCGCGTGGACGCCAGCGACC
TGTTCCTGGGCAAGCTGGCCGGCGTCAGCGAGCCCGAGGCCAAGCGCAAGATCATCGGTGGCCTGTTCGTGGACGTGTTC
AAGGCCGAGGCCGCCAAGCTCAAGGCAGGCGACGGTGGCCACAAGGGCGCCACCTTCCTGGCCCAGGGCACCATCTACCC
CGACGTCATCGAGTCGGGCGGTGCCAAGAGCAAGAAGGCCGTCACCATCAAGAGCCACCACAACGTCGGCGGCCTGCCCG
AGCAGCTCGGCCTGAAGCTGCTCGAACCCCTGCGCGACCTGTTCAAGGACGAAGTGCGCGAACTCGGCGTGGCCCTGGGC
CTGCCGCGCGAAATGGTCTACCGCCACCCCTTCCCGGGCCCGGGCCTGGGCGTGCGCATCCTGGGCGAAGTCAAGAAGGA
ATACGCCGACCTGCTGCGCCGCGCCGACGCCATCTTCATCGAGGAACTGCGCAACTGGACCGACGAAGCCACCGGCAAGA
ACTGGTACGACCTCACCAGCCAGGCCTTCACCGTCTTCCTGCCCGTCAAGAGCGTGGGCGTCATGGGCGACGGCCGCACC
TACGACTACGTCGTGGCCCTGCGCGCCGTGCAGACCAGCGACTTCATGACCGCCGACTGGGCCGAGCTGCCCTACGGCCT
GCTCAAGAAGGTGTCTGGCCGGATCATCAACGAAGTGCGCGGCATCAACCGGGTGACCTACGACGTTTCGACCAAGCCGC
CGGCGACGATCGAGTGGGAATGA

Protein sequence :
MTMQHDKILILDFGSQVTQLIARRVREAHVYCEVHPCDVSSDWVREFAADGRLKGVILSGSHASVYEVDDRAPDAVFELG
IPVLGICYGMQAMATQLGGKVEGSHTREFGYAEVRAHGHTELLKGIQDFATAEGHGMLKVWMSHGDKVTELPPGFKVMAS
TPSCPIAGMADEARRFYAVQFHPEVTHTVQGAALLNRFVREICAANADWIMGDYIEEAVAKIREQVGDEEVILGLSGGVD
SSVAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMEMFEGKLHAKVIRVDASDLFLGKLAGVSEPEAKRKIIGGLFVDVF
KAEAAKLKAGDGGHKGATFLAQGTIYPDVIESGGAKSKKAVTIKSHHNVGGLPEQLGLKLLEPLRDLFKDEVRELGVALG
LPREMVYRHPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRNWTDEATGKNWYDLTSQAFTVFLPVKSVGVMGDGRT
YDYVVALRAVQTSDFMTADWAELPYGLLKKVSGRIINEVRGINRVTYDVSTKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-127 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-127 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-127 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-112 49