Gene Information

Name : Cphy_0910 (Cphy_0910)
Accession : YP_001558034.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Unknown
Product : rRNA large subunit methyltransferase
Function : -
COG functional category : S : Function unknown
COG ID : COG1576
EC number : -
Position : 1162542 - 1163021 bp
Length : 480 bp
Strand : +
Note : SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA

DNA sequence :
ATGAAAATTACAGTAGTATGTGTTGGAAAAATAAAAGAAAAATATTTAACTATGGCAATTGAGGAGTATTCGAAACGTTT
GAGCAGGTATTGCAAGTTAGAGATAATCGAGTTAGCTGATGAAAAAACACCAGATAACGCATCACCTGCGGAAGAACTTC
AGATAAAGAAAAAAGAGGGCGAGAGGATATTAAAAAATATCAAGGACAATGCCTATGTCATTGCACTTGCAATTGAAGGG
AAGATGCTCTCGTCCGAAGAATTAGCAGATAAGATGCAGCTGCTTGGTGTTAACGGAGAAAGTCATCTTGCTTTTGTGAT
TGGTGGATCACTTGGGTTGGATAGTGAAGTTTTAGACAGGGCAGATTTTAAACTTAGCTTTTCTAAGATGACATTTCCTC
ATCAGGTTATGAGGACTATTTTATTGGAGCAGGTGTATAGAGGGTTTAGGATTATGAGTGGTGAACCGTATCATAAGTAA

Protein sequence :
MKITVVCVGKIKEKYLTMAIEEYSKRLSRYCKLEIIELADEKTPDNASPAEELQIKKKEGERILKNIKDNAYVIALAIEG
KMLSSEELADKMQLLGVNGESHLAFVIGGSLGLDSEVLDRADFKLSFSKMTFPHQVMRTILLEQVYRGFRIMSGEPYHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orfX YP_251938.1 rRNA large subunit methyltransferase Not tested SCCmec Protein 5e-46 62
unnamed BAG06184.1 conserved hypothetical protein orfX Not tested Type-VII SCCmec Protein 1e-45 59
unnamed BAB47681.1 open reading frame X Not tested Type-III SCCmec Protein 1e-45 59
SSP0026 YP_300116.1 rRNA large subunit methyltransferase Not tested SCC15305RM Protein 5e-45 59
unnamed BAC53844.1 open reading frame X Not tested SRImec-III and SCCmec-III region Protein 1e-45 59
SAR0024 YP_039501.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 2e-45 59
unnamed BAC57492.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 1e-45 59
SAV0024 NP_370548.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 2e-45 59
unnamed BAB72121.1 hypothetical protein Not tested Type-IVa SCCmec Protein 1e-45 59
unnamed BAB72138.1 open reading frame X Not tested Type-IVb SCCmec Protein 1e-45 59
unnamed BAC67575.1 open reading frame X Not tested Type-IVc SCCmec Protein 1e-45 59
unnamed BAA82243.1 orfX Not tested Type-II SCCmec Protein 1e-45 59
unnamed BAD24821.1 conserved hypothetical protein orfX Not tested Type-V SCCmec Protein 1e-45 59
orfX BAA86653.1 open reading frame X Not tested Type-I SCCmec Protein 1e-45 59
SERP2529 YP_190070.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 7e-45 58
orfXhom BAB83497.1 open reading frame X Not tested SCC 12263 Protein 2e-42 58
orfX AAL26648.1 unknown Not tested SCCcap1 Protein 3e-44 58
SE0023 NP_763578.1 rRNA large subunit methyltransferase Not tested SCCpbp4 Protein 7e-45 58