Gene Information

Name : Cphy_0741 (Cphy_0741)
Accession : YP_001557867.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 954274 - 956016 bp
Length : 1743 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: csc:Csac_1831 pyruvate kinase

DNA sequence :
ATGAGGAAAACAAAAATTGTTTGTACCTTAGGCCCGGCAACCGAAGATGATGCTGTATTGCGTCAGCTGATGATTGAGGG
GATGGATGTAGCCAGATTTAATTTCTCGCATGGTGATTATGAACAGCATACAAGAAATTATGAACGTATTCGCCGACTTA
GTGCGGAATTGAAATTACCGATTGCTACGTTACTTGATACCAAAGGACCAGAAATCCGTATTGGTACATTTGAAAACGGA
AAAATTGAATTAAAAAAGGGTCAAATCTTTACCCTAACAACAAATGATATTGTTGGAGATGAAACACAGGTTTCAATTAC
ATATAAAAACTTAATACGTGACATAAAAAATGGAGTTAAAATACTGATTGATGATGGTCTTATAGAGCTTAAAGTATTTA
ATATCACTGATACAGATATTATTTGTGAAGTTCTAAATGGTGGTATGATTTCAAATCATAAGGGTGTAAATGTACCTGGA
GTTGAATTATCCATGCCTTTTATTAGTAAACGTGATTATGAGGATATCGTATTTGGTATTGGGCAGGGTTTTGACTTTAT
TGCAGCTTCGTTTACAAGATGTGCAGATGACATAATCCAGATACGTAAAATATTGAATGAGTATAACTGTAATACAGTCA
ATATAATTGCAAAAATTGAAAATTTACAAGGTGTAAACAATATTGATGAGATAATTCGTGTGTCTGATGGTATTATGGTT
GCCCGTGGTGACATGGGTGTTGAAATTCCGTTAGAAGAAGTTCCTGTCATTCAAAAAATGATTATTAAAAAGGTTTACAA
TGCAGAGAAGCAAGTAATCACAGCGACTCAGATGCTTGATTCTATGATGAAGAATCCAAGACCAACAAGAGCTGAGGCGA
CGGATGTTGCGAATGCTATTTACGATGGAACTAGTGCCATTATGCTTTCCGGTGAAACAGCAGCAGGTTTATATCCTGTT
GAGGCATTAAGGACAATGGTTAAAATCGCAAAGCGAACCGAAGCAGATATCGATTATACATCACGATTTAGAAAGAGAGA
TAGTCTTACGAATCCGGATGTCACCAATGCAATCTCACATGCGACCGTTACAACAGCGATAGACCTTAATGCAGCTGCGA
TAATAACCGTAACAAAATCCGGTAAAACTGCAAGAATGATTTCAAAGTATCGTCCACCAAGTTCTATCATTGCATGTACC
ACCTACGAACATATATGCCGTCAGATGAATCTTTCCTGGGGTGTTGTACCGTTGTTAATCGAAGAGGAAGTGGATGCAAA
TACATTGTTTGAACATGCGGTGGAAGCAGCAGAAAAGGCAGGTTTTGTTAAGTCAGGTGAATTAGCTGTTATCACTGCTG
GAGTACCACTTGGAATTTCCGGTACTACCAATCTTATCAAGGTTCAAGTCGTAGGTCATATCTTAGTAAAAGGAAGAGGC
TTAATTGACCGTGAGGTATGCTCAAGTCTTTGCGTATGTAATGATACTGAGGAATTAAGAGAAACTTTTAAGCCAGGGGA
TATTATCGTTGTGAAAGAAACCAATAACGAGATGATGGAGCAATTAAAACAAGCAGCTGGTATTATTGTTGAGCAGGAGG
GGATTAATTCCCATGCTTCAATCGTTGGGTTAAGCCTTGATATTCCAGTAATTCTTGGTGCTGAAAATGCAACAAAGATA
TTACGTACTGGTTCAATCGTAACACTAGATGGTAAAGAAGGGAATGTATCTGGTAATCGATAA

Protein sequence :
MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRRLSAELKLPIATLLDTKGPEIRIGTFENG
KIELKKGQIFTLTTNDIVGDETQVSITYKNLIRDIKNGVKILIDDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPG
VELSMPFISKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKILNEYNCNTVNIIAKIENLQGVNNIDEIIRVSDGIMV
ARGDMGVEIPLEEVPVIQKMIIKKVYNAEKQVITATQMLDSMMKNPRPTRAEATDVANAIYDGTSAIMLSGETAAGLYPV
EALRTMVKIAKRTEADIDYTSRFRKRDSLTNPDVTNAISHATVTTAIDLNAAAIITVTKSGKTARMISKYRPPSSIIACT
TYEHICRQMNLSWGVVPLLIEEEVDANTLFEHAVEAAEKAGFVKSGELAVITAGVPLGISGTTNLIKVQVVGHILVKGRG
LIDREVCSSLCVCNDTEELRETFKPGDIIVVKETNNEMMEQLKQAAGIIVEQEGINSHASIVGLSLDIPVILGAENATKI
LRTGSIVTLDGKEGNVSGNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-94 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-94 47
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-94 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-93 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cphy_0741 YP_001557867.1 pyruvate kinase VFG0479 Protein 1e-94 47