Gene Information

Name : ureB (Cphy_0688)
Accession : YP_001557814.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0832
EC number : 3.5.1.5
Position : 892470 - 892790 bp
Length : 321 bp
Strand : -
Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzym

DNA sequence :
TTGAAACCAGGAGAATATATTTTAAAAAACGAGGAAATTACATGCAATGAAGGCAGAAGAACTATTAAGATAACAGCTGT
CAACACCGGGGATCGCCCTGTTCAAGTTGGATCTCACTATCATTTTTATGAAGTAAATTCTGCAATACAATTTAACAGGG
AAGAAACGATAGGCATGCACCTTGATATACCAGCGGGTACTGCGGTTAGATTTGAGCCTGGTGACTCAAAAGAAGTTTCG
TTGGTGGATTATGCAGGAGAACGTTTCGTATACGGATTTAATAATAAGATAGACGGTAAATTGGATACTAGGAGGAATTG
A

Protein sequence :
MKPGEYILKNEEITCNEGRRTIKITAVNTGDRPVQVGSHYHFYEVNSAIQFNREETIGMHLDIPAGTAVRFEPGDSKEVS
LVDYAGERFVYGFNNKIDGKLDTRRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureB YP_005682175.1 Urease beta subunit Not tested PiCp 7 Protein 1e-26 63
ureB YP_005684267.1 Urease beta subunit Not tested PiCp 7 Protein 1e-26 63
ureB YP_005686359.1 Urease beta subunit Not tested PiCp 7 Protein 1e-26 63
ureB YP_003784326.1 urease subunit beta Not tested PiCp 7 Protein 6e-27 63
ureB NP_286679.1 urease subunit beta Virulence TAI Protein 2e-20 55
ureB NP_287087.1 urease subunit beta Not tested TAI Protein 2e-20 55