Gene Information

Name : Cphy_2900 (Cphy_2900)
Accession : YP_001559997.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3557688 - 3559112 bp
Length : 1425 bp
Strand : -
Note : KEGG: cdf:CD3394 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGCAGAAAAAAACGAAAATTGTTTGTACCTTAGGGCCAGCGACTTCAACCGAAGAGATGATTAAGGAATTGTGTTTAAG
TGGAATGGATATTGCGAGATTGAATTTCTCACACGGAAATCATGAAGGTCATGGTGAAATGATTGCTAAAATTAAGAAGG
TTCGTGAAGAATTAGGTCTTCCAATCGCGATTCTTCTTGACACAAAAGGACCAGAGATTCGTACCGGACTTGCGGAAAAT
GGTAGAGAGTTTACCCTAGAAAAAGGCGAACAGGTAATTGTAACAACAGAGGATGTTCCTTGTAATAGTTCAATTATCAG
TGTTACTTATAAAAACCTTCCAGAGGACGTTGTGGTGGGAGGATCAATCTTAATCGCAGATGGTCTGATTGAGTTAAAAG
TTAAAAAAGTAGAAGACGACGAAAAAGTAATCTGTGAAGTTGTTAATGGTGGTGAGCTTGGTAGTAGAAAAGGTGTAAAC
CTTCCAAACGTAAAGCTTAAGCTTCCAGCAATCACTGAGCAGGATAGAGCAGATATCATCTTTGGTATCAATGAAGGAGT
TGACTTTATCGCAGCTTCTTTTATCCGTAATGCAGAAGCGATTCGTGAAATTCGTGGTATCATTCATGACTGCAATTCTG
ATATCGCAATTATTGCGAAAATCGAGAATATGGAAGGTATGGAAAACCTAGACGAAATTATTGCAGAAACAGACGGAATT
ATGGTTGCTCGTGGTGACCTTGGTGTAGAAGTAGAGCCAGAAACTCTTCCATACATCCAAAAGACCATGATTCAAAAATG
TAATGCGGCATTTAAGCCAGTTATTACAGCAACTCAGATGTTAGATTCTATGATTCGTAATCCACGTCCAACTCGTGCAG
AGGTTACAGACGTTGCGAATGCGATCTATGATGGAACAGATGCTATCATGTTATCTGGAGAAACAGCTGCTGGTAAATAT
CCTATTGAAGCAGTACAGATGATGGCGAAGATTGCAAAAGAAACAGAAACACATTACGAGTCTATTACATGTAACGAGAG
TGAATTTGTACCAGGCAGCGAAGATGTTTCATGCGCAATTAGCTATTCCGCAGTTGCAACAGCTGGACGCCTTGATGCTA
AATTAATCATTGCTTCTAGCTTCTCTGGTTATACCGCTCGTTTGGTTTCAAAATACCATCCAAAGTGTCCAATCATTGGA
TTATCTCCTTTAGATCGTACACTTCGTAAGATGCAGATTTACCGTGGTGTTCAGCCATTAAAGGTAGATGAAGTGAATTC
TACTGACCATCTTTTAGATGAAGCAGTGAAGACGGTAAGTAAACATGGCTATGTAAATGTTGGTGATGTTGTGATTTTAA
CAGCAGGTGTACCAGCTGGTAAGTCAAGCGTAACTAATATGATAAAAGCGGTTATTATTGACTAA

Protein sequence :
MQKKTKIVCTLGPATSTEEMIKELCLSGMDIARLNFSHGNHEGHGEMIAKIKKVREELGLPIAILLDTKGPEIRTGLAEN
GREFTLEKGEQVIVTTEDVPCNSSIISVTYKNLPEDVVVGGSILIADGLIELKVKKVEDDEKVICEVVNGGELGSRKGVN
LPNVKLKLPAITEQDRADIIFGINEGVDFIAASFIRNAEAIREIRGIIHDCNSDIAIIAKIENMEGMENLDEIIAETDGI
MVARGDLGVEVEPETLPYIQKTMIQKCNAAFKPVITATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKY
PIEAVQMMAKIAKETETHYESITCNESEFVPGSEDVSCAISYSAVATAGRLDAKLIIASSFSGYTARLVSKYHPKCPIIG
LSPLDRTLRKMQIYRGVQPLKVDEVNSTDHLLDEAVKTVSKHGYVNVGDVVILTAGVPAGKSSVTNMIKAVIID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-83 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-82 47
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-83 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cphy_2900 YP_001559997.1 pyruvate kinase VFG0479 Protein 3e-83 47