Gene Information

Name : guaA (Cphy_0264)
Accession : YP_001557390.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 329775 - 331298 bp
Length : 1524 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGTAATTGTACTTGATTTTGGTGGACAGTACAATCAGCTGATTGCAAGACGTGTCAGAGAATGTAATGTTTACTGTGA
AGTTATGCCTTATAACATCAGTTTGGAAAAAATAAAAGAATTAAATCCAAAGGGTATTATTTTTACCGGCGGACCAGCAA
GCGTTTATGCGGAAGGTGCTCCACATTGTGATAAGGGTATATTTGAGTTAGGGATTCCAGTGCTTGGTATCTGCTACGGC
GCCCAGTTAATGACACATCTTCTTGGAGGATCAGTAACGAGCGCTGAGGTAAGAGAATATGGTAAAACTGAGATTAAGGT
GAATACCACTTCTAAATTATTTAAAGACGTTGCTGAAAATACAATCTGTTGGATGAGCCATACAGACCATATCAAGACTC
CTGCAGAAGGATTTGTAGTTACTTCAAGTTCCGATTCCTGTCCAGTGGCCGCAGTTGAAATGGTAGATAAGAAGCTCTAT
TCAGTGCAGTTCCACCCAGAAGTAGTTCACACACAAGAAGGTACTAAGATGCTTCGTAACTTCTTATATGAAGTATGTGA
GTGTAACGGTGACTGGAAGATGGCATCCTTTACAGAGGAATCCATTCAGGCTTTACGTGATAAAATCGGTGATAAGAAAG
TACTTTGTGCTTTATCCGGTGGTGTAGACTCCTCTGTAGCAGCAGTTATGATCTCTAAAGCAGTTGGAAAGCAGTTAACC
TGTATCTTCGTAGACCACGGTTTACTTCGTAAGAACGAAGGTGACGAGGTTGAGCAGATCTTTACAACTCAGTTTGATGT
AAACTTTGTACGTGTAAATGCACAGCAGAGATTCTATGATAGATTAGCTGGAGTTACAGATCCAGAAACAAAACGTAAGA
TTATCGGTGAGGAATTCATCCGTGTATTCGAAGAAGAAGCAAAGAAAATTGGAACTGTTGATTTCTTAGCACAGGGAACC
ATTTACCCAGATGTTATCGAATCCGGTCTTGGCAAATCCGCAGTGATTAAATCCCACCACAACGTAGGTGGTCTTCCAGA
GCATGTTGATTTCAAGGAAATTGTAGAGCCACTTCGCCTTCTCTTTAAAGATGAAGTTCGTAAGGCTGGTTTAGAGCTTG
GAATCCCAGAAAAATTAGTATTCCGTCAACCATTCCCAGGACCAGGACTTGGTATCCGTATCATCGGTGAAGTTACTCCT
GAGAGAATTAAGCTTGTTCAGGAAGCAGACGCTATCTACCGTGAGGAAATTGCCAATGCAGGTCTTGACCGCAGTATCGG
ACAGTACTTCGCAGCATTAACAAACATGCAGTCTGTAGGATGTATGGGTGATGAGAGAACTTACGATTACGCAATTGCAC
TTCGTGCAGTAACAACAACTGACTTCATGACCGCTGAGTTTGCTGAACTTCCTTGGGAGTTACTTGGCAAGGTTTCAAGC
CGTATTGTAAATGAAGTTAAGGGTGTTAATAGAGTACTTTATGATTGTACGGGGAAACCACCGGCAACGATTGAGTTTGA
GTGA

Protein sequence :
MVIVLDFGGQYNQLIARRVRECNVYCEVMPYNISLEKIKELNPKGIIFTGGPASVYAEGAPHCDKGIFELGIPVLGICYG
AQLMTHLLGGSVTSAEVREYGKTEIKVNTTSKLFKDVAENTICWMSHTDHIKTPAEGFVVTSSSDSCPVAAVEMVDKKLY
SVQFHPEVVHTQEGTKMLRNFLYEVCECNGDWKMASFTEESIQALRDKIGDKKVLCALSGGVDSSVAAVMISKAVGKQLT
CIFVDHGLLRKNEGDEVEQIFTTQFDVNFVRVNAQQRFYDRLAGVTDPETKRKIIGEEFIRVFEEEAKKIGTVDFLAQGT
IYPDVIESGLGKSAVIKSHHNVGGLPEHVDFKEIVEPLRLLFKDEVRKAGLELGIPEKLVFRQPFPGPGLGIRIIGEVTP
ERIKLVQEADAIYREEIANAGLDRSIGQYFAALTNMQSVGCMGDERTYDYAIALRAVTTTDFMTAEFAELPWELLGKVSS
RIVNEVKGVNRVLYDCTGKPPATIEFE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-151 59
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-151 59
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-151 59
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-131 53