Gene Information

Name : Cphy_2214 (Cphy_2214)
Accession : YP_001559319.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2733925 - 2735244 bp
Length : 1320 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: cth:Cthe_2340 UDP-glucose/GDP-mannose dehydrogenase

DNA sequence :
ATGGATTTATATGAGAGATTGATTAGCGGGGATGAGAAATTAGCTGTGGTAGGGCTAGGATATGTTGGATTACCGATAGC
AGTAGCTTTCGCTAAGAAAATTAAGACAATTGGATTTGATATTAACCAACAAAAGATTAGCGAGTATTTAAATGGGAAAG
ATCCTACACAGGAGGTTGGAACAGAAGTAATCAGAAAAACCACTCTGGAATTCACTTGTAGCGAGGAAAAACTAAGGGAA
TCTAAATTTATCATCGTAGCAGTACCAACTCCAATCCATACAGATAAAACACCGGATCTATCGCCTGTAACAGGCGCGTG
TGAAATAGTCGGACGCAATCTTACAAAGGATGCAATTGTTGTATTTGAATCTACCGTTTACCCAGGGGTGACTGAGGAGG
TATGTATTCCAATTCTGGAGAATATCTCAGGCCTCAGCTGTGGAACAGATTTTAAAATAGGCTATTCACCGGAACGTATC
AATCCGGGGGACAAGCATCATAAATTAAATAATATCATAAAAATTGTATCCGGAATTGATACGGAAGCAAGAGAAATCAT
TGCTAAGGTTTACGAATTAATCATTGATGCAGGCGTGCACCTTGTAACGAACATAAAGACAGCGGAAGCTGCGAAGCTTG
TAGAGAATGCGCAGAGAGATATTAACATTGCATTTATGAATGAACTAGCTATGGTATTTGAGAAAATGGACATTAACACG
CAAGAGGTCGTTGAGGCAATGAACACGAAGTGGAATGCTCTCGGTTTTACACCCGGTTTAGTAGGCGGCCACTGCATCGG
TGTAGATCCATATTATTTTATTTATCAGGCAGAAAAATTAGGGTATCATTCTCAGATTATTTTATCAGGCAGAAAGATTA
ACGATGGTATGGGTTCTTTTATCGGTGATATTGTAATTAAGAAGCTGATAAAGACAAACAAATTAGTGAATCAAGCAAAA
ATATATATTCTTGGTATCACCTTTAAAGAAAACTGCCCCGATATTAGAAATTCTAAAGTAATTGACATTATTAACAGACT
GAAAGAATATGACGTGACTGTTAATGTTGTGGATCCAGTTGCTGATGAGAAGGAAGTAAAATCATTTTATGATATAAATA
TGGTGAAGCTTTCTGAGGTGAAAGAAGCAGATTGTATTATAATAGCGGTTGCACATAATGAATTTAGGAAATTATCAAAA
GATGACCTGGATCAAATGTTTCGTGCATTACCAGCCGAAGAAAAGGTTGTGATTGACATAAAAAGTATTTTTCCTAAGAG
TGAAATGGAGGCAATGGGATATTCCTATTGGAGCCTATAA

Protein sequence :
MDLYERLISGDEKLAVVGLGYVGLPIAVAFAKKIKTIGFDINQQKISEYLNGKDPTQEVGTEVIRKTTLEFTCSEEKLRE
SKFIIVAVPTPIHTDKTPDLSPVTGACEIVGRNLTKDAIVVFESTVYPGVTEEVCIPILENISGLSCGTDFKIGYSPERI
NPGDKHHKLNNIIKIVSGIDTEAREIIAKVYELIIDAGVHLVTNIKTAEAAKLVENAQRDINIAFMNELAMVFEKMDINT
QEVVEAMNTKWNALGFTPGLVGGHCIGVDPYYFIYQAEKLGYHSQIILSGRKINDGMGSFIGDIVIKKLIKTNKLVNQAK
IYILGITFKENCPDIRNSKVIDIINRLKEYDVTVNVVDPVADEKEVKSFYDINMVKLSEVKEADCIIIAVAHNEFRKLSK
DDLDQMFRALPAEEKVVIDIKSIFPKSEMEAMGYSYWSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-106 52
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-94 48
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-94 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cphy_2214 YP_001559319.1 nucleotide sugar dehydrogenase VFG0431 Protein 1e-94 48