Gene Information

Name : hemC (Cphy_1786)
Accession : YP_001558895.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2201182 - 2202087 bp
Length : 906 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAAAAAGCAAAAAATCGTGGTGGGTAGTCGAGATAGTAAATTAGCTGTAATGCAGACGGAATTAATTATGCACGAGAT
TAATCGCAATAACCCGGAAATAGAGTTAGAGTTAGTTACGCTAAAGACTACCGGTGACTTAATACTAGATCAAAGTTTAG
ATAAGATTGGGGGAAAAGGTCTCTTTGTTAAGGAATTAGACCTAGCATTACTAGATGGCAGAATTGATATAGCAGTTCAT
AGTTTAAAGGATATGCCAATGGAAGAGAACAAAGAACTACCGATTGTGGCATTACCAAAGCGCGGGGATGCGAGAGATGT
ATTAGTGTTGCCAAAAGGATGTGAATTCATTGAATATGAAGATATGAACTTATACTATCAAAATATCGGATCTTCTAGTG
CAAGGAGAAAGTTACAAATACAAAAATTATTGCCAAGTGCTGGTACTAGCGGTGTTCGCGGCAATGTTATTACAAGACTG
GACAAATTAGACAGAGGAGAGTATACTTCTTTGATTTTAGCAGCAGCAGGGTTACAAAGAGTTGGCTTACCACATCGTAT
CAGTCATTATTTTTCAGTGGAAGAGATGATTCCGGCAGCAGGTCAAGGTATACTGTCCATTCAAGCTAGGAGAGATTTAA
ATGTTGATTTCCTAGAAAATATCAAGGATGCTAATACAACATACGCTTCCTTAGCAGAGAGAAGCTTTGTCCGCACCTTA
GATGGGGGTTGTTCTTCACCAATCGCAGCATATGCAGCAGTAGAAGGGGAAGAATTGAAGTTAGTCGGCTTATATTATAA
TGAGAAAACAACAGAACATAGAGTTGCCACAGTTGTAGACCACAAGGAAAGAGCAGAAAGAGTCGGAGAACAATTGGCAT
TACGCTTAAGAGGTGAGATTGGATGA

Protein sequence : 
MKKQKIVVGSRDSKLAVMQTELIMHEINRNNPEIELELVTLKTTGDLILDQSLDKIGGKGLFVKELDLALLDGRIDIAVH
SLKDMPMEENKELPIVALPKRGDARDVLVLPKGCEFIEYEDMNLYYQNIGSSSARRKLQIQKLLPSAGTSGVRGNVITRL
DKLDRGEYTSLILAAAGLQRVGLPHRISHYFSVEEMIPAAGQGILSIQARRDLNVDFLENIKDANTTYASLAERSFVRTL
DGGCSSPIAAYAAVEGEELKLVGLYYNEKTTEHRVATVVDHKERAERVGEQLALRLRGEIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-40 43
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-40 43