Gene Information

Name : hemC (Cphy_1370)
Accession : YP_001558484.1
Strain : Clostridium phytofermentans ISDg
Genome accession: NC_010001
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1709741 - 1710628 bp
Length : 888 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGAATAATTCGTATCGGAAGCAGAGAAAGTGAACTGGCAGTTAGACAGTCGAGAATACTGATTGATTCTATAAAACA
ATATCATAATGAAATAGAGACTGAGCTTATTACCATGAAGACGACAGGAGATATCATACTGGATAAAAGCCTAGACAAAA
TTGGAGGAAAAGGTCTCTTTGTAAAGGAGCTAGATTTAGCGCTTATCGAAGGGAGAAGTGACCTGTCGGTACATAGCTTA
AAGGATATGCCAATGGAAACGCCGGAGGAATTACCTATTTTAGCATTTTCAAAAAGGGAGGATCCAAGAGATGCGCTGGT
TTTACCATTAGGATGTACAGAAATTGACCCTGTTTTACCAATTGGATGTTCCAGCCAGAGACGAATGCTTCAACTAAAAA
AGATTTATCCAGGTGCCAATTATAAAGGAATCAGAGGAAATGTACTTACTAGGCTTGAGAAACTTGATAGAGGAGAATAT
GGTGCTCTTGTCTTAGCTGCGGCAGGGTTAAAGAGATTGGGATTAGAAAGCCGTATCAGCCGAATCTTTACGACGGAGGA
AATTATTCCAGCTGCCGGACAGGGGATACTGGCTGTTCAGGGAAGAGCGGGTGAAAGTTATGAATTCTTAAAACAATTTC
ATAATGAAGAGGCAACCTTTCAAGCAGTATGTGAGAGAGCATTTGTAAAGACATTGAATGGAGGATGCAGTTCCCCGGTA
GCAGCATATGCAAAGGTTGAAGATGAAATGATTACAGTAACAGGCTTATATTTCGATGAAATAACCGGTGATTATATCAC
TGGAAATCTTACCGGAAAGAAGGAAGATGCAGAGCAACTGGGGGAGATGTTAGCGAATAAGCTTAGAACGGAATGGTGCA
TGCGATGA

Protein sequence :
MRIIRIGSRESELAVRQSRILIDSIKQYHNEIETELITMKTTGDIILDKSLDKIGGKGLFVKELDLALIEGRSDLSVHSL
KDMPMETPEELPILAFSKREDPRDALVLPLGCTEIDPVLPIGCSSQRRMLQLKKIYPGANYKGIRGNVLTRLEKLDRGEY
GALVLAAAGLKRLGLESRISRIFTTEEIIPAAGQGILAVQGRAGESYEFLKQFHNEEATFQAVCERAFVKTLNGGCSSPV
AAYAKVEDEMITVTGLYFDEITGDYITGNLTGKKEDAEQLGEMLANKLRTEWCMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-44 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-44 42