Gene Information

Name : pykF (P9211_08471)
Accession : YP_001550732.1
Strain : Prochlorococcus marinus MIT 9211
Genome accession: NC_009976
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 741389 - 743131 bp
Length : 1743 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGACAAACATACATTTTAAAAGAAGGACCAAGATTGTTGCGACGATTGGACCAGCAACTGAAAGTAAAGAACGTATTAC
AGAGCTTGTTGAAGCTGGCGCAACAACCTTCAGGCTTAATTTTTCGCACGGAGACCATAGCGAGCATGCCAAGCGAATAG
AAACGATCAGACTAGTCGAGGCGAAGCTTGGGGTTAAGATTGGTATTCTTCAAGATCTTCAAGGACCCAAAATACGTCTG
GGTAGATTTAAAGATGGTCCTATAAGACTAAATAGTGGTGACAAGTTCGTACTTACCTCAAAGGACGTAGGTTGTAATAA
CGAAATAGCTAATGTCACATATGAAAAGTTAGTCAGTGAGGTGTCAATAAATAAACGAATACTTTTAGATGATGGCAGAG
TGGAGATGGTCGTGGAAAGGGTAGATAAACTTGAGGAAAAGCTACATTGCAAAGTCGTTGTAGGTGGAATGTTATCTAAT
AATAAAGGTGTAAATTTCCCTGATGTTCAGTTATCAATAAATGCTTTGACTCCAAAGGATAAGATCGATCTTTCCTTTGG
ACTTTCTCAGAGTATTGACTGGGTAGCACTTAGTTTTGTTAGGAACCCTGATGATATAAAAGAGATTAAAGAGCTTATTA
GAAGTCATGGATATACCACACCAGTAGTTGCAAAAATAGAGAAGTTTGAAGCTATTGATCAAATAGATGCCATTCTTCGC
TTATGTGACGGTGTAATGGTTGCTAGGGGCGATTTGGGTGTAGAGGTGCCTGCTGAAGAAGTCCCATTACTACAAAAAGA
GCTCATTAAAAAATCCAATAGTTTGGGAATTCCAATAATTACGGCAACGCAAATGCTTGACTCTATGGCTTCTAGCCCAA
GACCAACCAGGGCAGAAGTTAGTGATGTTGCAAATGCCATTCTTGATGGCACTGATGCTGTAATGCTTTCGAACGAAACT
GCTGTAGGAGACTATCCAATAGAAGCTGTGAAAACCATGGCGACTATTGCCAAACGAATTGAGAAAGATTACCCGCAAAG
AGCGCTAGAAAGCCATCTACCAAGCACCATTCCAAATGCAATTAGTGCTGCTGTTAGCTCTATATCAAGACAATTAAATG
CCTCTGCAATATTGCCATTAACTAAAAGTGGTTCAACTGCTCATAATGTAAGCAAATTCAGGCCTCCAACCCCTATAGTT
GCTGTAACTAATGAAACTGATGTTGCAAGAAGGCTCCAATTAGTTTGGGGAGTTACTCCAATAGTTATTAAAGAACAAGA
AACTACAACTAAAACATTTAACTTAGCCATGGAGATGGCCCAGGGTATGGGCTTACTTAAGCCAGGTGCTCTTGTGGTCC
AAACAGCTGGCACAATAACTGGAGTAAGTGGATCAACTGACCTAATAAAGGTTGGCATAGTTAATGACATAGTTGCCCGT
GGAAATTCTGAAGGCAATAATTCTGTTTGTGGGAAAGTGAGAATTGCAAAGGAACAAAAAGATTTATCCGAATTGAAGAA
AGGTGAAATATTAGTTTTAGATAAAAATATTAATAATTATTCTCAAGCTTTGAAATATGCAGCAGGAATTATATTAGAAG
GAACCTTAAATATAGAAAATAATAATACTGTGCCAACAATATATAATGTAAAAGGTGCTACAGATATCCTAAGAGATGGT
GATATGGTCACACTAGTCCTAAAGGAAGGGACTATTTGTAGAGGTGAAATTCTTAACGATTAA

Protein sequence :
MTNIHFKRRTKIVATIGPATESKERITELVEAGATTFRLNFSHGDHSEHAKRIETIRLVEAKLGVKIGILQDLQGPKIRL
GRFKDGPIRLNSGDKFVLTSKDVGCNNEIANVTYEKLVSEVSINKRILLDDGRVEMVVERVDKLEEKLHCKVVVGGMLSN
NKGVNFPDVQLSINALTPKDKIDLSFGLSQSIDWVALSFVRNPDDIKEIKELIRSHGYTTPVVAKIEKFEAIDQIDAILR
LCDGVMVARGDLGVEVPAEEVPLLQKELIKKSNSLGIPIITATQMLDSMASSPRPTRAEVSDVANAILDGTDAVMLSNET
AVGDYPIEAVKTMATIAKRIEKDYPQRALESHLPSTIPNAISAAVSSISRQLNASAILPLTKSGSTAHNVSKFRPPTPIV
AVTNETDVARRLQLVWGVTPIVIKEQETTTKTFNLAMEMAQGMGLLKPGALVVQTAGTITGVSGSTDLIKVGIVNDIVAR
GNSEGNNSVCGKVRIAKEQKDLSELKKGEILVLDKNINNYSQALKYAAGIILEGTLNIENNNTVPTIYNVKGATDILRDG
DMVTLVLKEGTICRGEILND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-80 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_001550732.1 pyruvate kinase VFG0479 Protein 1e-81 44