Gene Information

Name : guaA (P9211_00371)
Accession : YP_001549922.1
Strain : Prochlorococcus marinus MIT 9211
Genome accession: NC_009976
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.4.1
Position : 35605 - 37251 bp
Length : 1647 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAAGTTTTGTCTTGATGTTTTCTCTAGTCTAACTTTATGCAGATTCTTGTTTGATATGTCTTCTGACTCACTGCTTAA
AAGCCAAAGGAGCCCCTCAATAGTCATCCTTGATTTTGGCTCACAATATTCTGAATTGATAGCTCGACGAATTAGAGAGA
CAGAAGTGTATTCAATTGTTTTGAGTTACAGCACTTCAGCAGCAGAATTACGCAAATTAGCTCCCAAAGGCATCATTTTG
AGCGGAGGTCCTAGTTCAGTTTATACAGCTTCAGCACCTCTATCTGATCCTGAGATTTGGGATTTGGACATTCCCGTTCT
TGGTGTTTGTTATGGGATGCAGGTAATGGTGCAACAGTTAGGTGGACATGTAACTGCTGCAGTTGGTAAGGCTGAGTATG
GTAAAGCACCTTTGCATGTTGATGATCCAACTGCATTGCTCACGAACGTCGAGAGTGGATCGACAATGTGGATGAGTCAT
GGCGATTCTGTAGATAAACTTCCGAGAGGCTTTGTTCGTTTAGCCCATACAAGCAATACTTTAGAGGCTGCTATCGCTTT
ACATACCAAACGTTTCTACGGTGTTCAGTTTCATCCAGAAGTTGTTCATTCAACGCAAGGGATGGTAATGATAAGGAATT
TTGTTTATAACATTTGCTGTTGTCAGCCTGATTGGACAACCAGCACTTTTATCGATGAAGCAATAAGTACGGTTAGAAGT
CAAGTAGGAGATAAAAAGGTTTTGCTTGCTTTATCAGGAGGTGTAGATTCTTCAACCTTAGCTTTTCTACTTAAGCGTGC
TATTGGTGATCAATTAACTTGCATGTTTATTGATCAAGGTTTTATGCGAAAAGGTGAACCTGAGTTTTTGATGGAATTTT
TTGATCAAAAATTTAAAATTAATGTTCAATATATTAATGCGCGTGAGCGCTTTATTTCTAAACTCCAGGGAATCTCTGAT
CCAGAGGACAAAAGAAAAGTTATAGGCAGGGAATTTATTCGTGTTTTCGAGGAAGAAAGTGAACGCCTCGGACCTTTTGA
CTATCTTGCGCAGGGCACCCTATATCCAGATGTTATAGAAAGTTCAGGGACAAATTTAGACCCTAAAACTGGAGAAAGAA
TAGCTGTGAAAATTAAGAGTCATCATAATGTTGGTGGCCTACCAAAGGATCTTCAATTTAAATTAGTTGAACCTTTAAGA
ATGTTATTTAAAGATGAGGTAAGGAAAGTAGGCAGAGCACTTGGACTACCTGAAGAAATAGTTGGTAGACACCCTTTTCC
TGGCCCTGGCTTAGCAATAAGAATTCTTGGAGAAGTTACTGATGAGAAATTAAATTGTCTACGTGATGCAGATTTAATCG
TTCGTGAGGAAATTAATCGAGCAGGTTTATATCATGAAATATGGCAGGCTTTTGCTGTTTTATTGCCAGTCTGCTCTGTT
GGTGTCATGGGTGATCAACGTACTTATGCATGGCCGATTGTTGTGAGATGTGTTTCTAGCGAAGATGGCATGACAGCTGA
TTGGTCACGGTTACCTGATTCACTTTTGCAAATTATTTCTAATCGAGTAGTGAATGAGGTTAAGGGCGTTAATCGCGTTG
TTTTAGATATAACAAGTAAGCCACCTGGAACAATTGAGTGGGAATAG

Protein sequence :
MKFCLDVFSSLTLCRFLFDMSSDSLLKSQRSPSIVILDFGSQYSELIARRIRETEVYSIVLSYSTSAAELRKLAPKGIIL
SGGPSSVYTASAPLSDPEIWDLDIPVLGVCYGMQVMVQQLGGHVTAAVGKAEYGKAPLHVDDPTALLTNVESGSTMWMSH
GDSVDKLPRGFVRLAHTSNTLEAAIALHTKRFYGVQFHPEVVHSTQGMVMIRNFVYNICCCQPDWTTSTFIDEAISTVRS
QVGDKKVLLALSGGVDSSTLAFLLKRAIGDQLTCMFIDQGFMRKGEPEFLMEFFDQKFKINVQYINARERFISKLQGISD
PEDKRKVIGREFIRVFEEESERLGPFDYLAQGTLYPDVIESSGTNLDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLR
MLFKDEVRKVGRALGLPEEIVGRHPFPGPGLAIRILGEVTDEKLNCLRDADLIVREEINRAGLYHEIWQAFAVLLPVCSV
GVMGDQRTYAWPIVVRCVSSEDGMTADWSRLPDSLLQIISNRVVNEVKGVNRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-127 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-127 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-127 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-123 52