Gene Information

Name : tktA (P9211_17351)
Accession : YP_001551620.1
Strain : Prochlorococcus marinus MIT 9211
Genome accession: NC_009976
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1561461 - 1563470 bp
Length : 2010 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTCGCTGCGCCCGCTTCACTCGATAAGCTTTGCATCAACAGCATAAGAATGCTTGCAGTTGATGCTGTTAATAAATC
CAAAAGCGGACATCCCGGTCTTCCAATGGGATGTGCACCAATGGGATATACGCTTTGGGATAAGTTCTTAAATCACAACC
CCAAAAACCCCAAATGGTTTAACCGAGACAGGTTTGTTCTTTCAGCCGGTCATGGTTGCATGTTGCTATATGCCCTTTTG
CATCTCACGGGTTATGAATCAGTAACGATTGAAGATATTAAACAATTTCGTCAGTGGGGGGCCAGAACACCCGGTCATCC
AGAAACTTTCGAAACGCCTGGTGTAGAGGTTACAGCAGGCCCATTAGGAGCAGGAATTTCCAATGCTGTAGGACTTGCCA
TTGCCGAATCTCATCTGGCTGCAAAATTCAATAAGCCAGATTTTTCTTTAGTTGATCATTTCACCTATGTGATCATGGGA
GACGGTTGTAATCAAGAAGGAGTTGCATCAGAAGCATGCTCTCTTGCAGGGCACTTGAAATTAGGAAAATTAATTGCTCT
TTATGACGATAATCACATCACAATTGATGGAAAAACTGATGTTTCATTCACAGAAGATGTACTAAAGCGATATGAGTCTT
ATGGATGGCATGTTCAACATGTTTCAGATGGCAATACAGATGTAGATGCCATTGCTAAAGCAATCCAACAGGCTAAAGAA
GTAACTGACAAACCATCCATCATTAAAATCACAACAACCATTGGATATGGTTCACCTAATAAAAGTGATACTGCTGGAGT
TCATGGGGCACCCCTAGGCGAGGAAGAGGCTGAGCTTACACGACAAGCATTGGGATGGTCTTATGGCCCTTTTGAAGTAC
CTCAAGAGGCATATGACCAATTGCGTCAAGCAATTGATAAAGGAGCAAAGTCCGAAGCTGTATGGAATGAATTATTAGAA
AGTTATCGCTCTAAATATCCTGATGAATCAATTGAATTTGAAAGAATGTTGAGGGGCGAACTCCCAAGCAATTGGGACCA
AAGTCTTCCTAGTTACACCCCTGAAGATAAAGGTTTGGCTACGAGAAAACACTCTCAGATTTGTTTAGGAGCATTAGGCC
CCAATCTGCCTGAGTTAATTGGAGGATCAGCAGACTTAACCCATTCAAATTACACAGATATCCAAGGGGAAACTGGTTCG
TTTCAAGCTGAGAGTCCTGAGAAACGCTATTTACATTTTGGAGTCAGAGAACATGCAATGGCAGCCATCCTGAATGGAAT
TGCTTATCACGGCAGTGGTTTAATCCCTTATGGAGGAACATTTTTAGTGTTTGCTGACTACATGAGAGGGTCAATGAGAC
TGTCTGCACTCAGTGAACTTGGAGTGATCTACGTCCTCACCCATGATTCAATTGGCGTAGGTGAAGACGGCCCAACACAC
CAACCAATAGAAACAATTCCCTCTTTGCGCGCAATGCCAAATATGCTTGTCTTCCGCCCAGGGGATGGTAATGAAACTAG
TGGTGCATACAAATTAGCGATCCAAAACCGCACTAGACCTAGTGCTCTATGTCTCAGCAGACAAGGCATGCCAAATCAAG
AAAATTCTTCTATTGAAAAAGTATCCTTTGGAGGATATGTTCTTGAAGATTGCGAAGGTACTCCTGAGTTAATACTTATA
GGAACAGGAAGTGAATTGTATCTTTGTGTTGATGCAGCTAAAGAGTTAACAAAACAAGGGCGAAAAGTGAGAGTTGTTTC
AATGCCATGTGTTGAACTATTTGAGGAACAAAGCTCTTCATATAAAGAAGAGGTTTTACCATCAGATGTAAGGAAGCGAA
TTGTCGTTGAAGCAGCGGAAACATTTGGATGGCATAAATATATTGGTCTTGATGGAGATAGCATTACAATGAGTGGATTT
GGTGCTTCTGCACCAGGTGGAACTTGTATGGAGAAATTTGGATTTACGCTCGAGAATGTATTAAATACTGCAAATAATTT
ATTAACTTAA

Protein sequence :
MVAAPASLDKLCINSIRMLAVDAVNKSKSGHPGLPMGCAPMGYTLWDKFLNHNPKNPKWFNRDRFVLSAGHGCMLLYALL
HLTGYESVTIEDIKQFRQWGARTPGHPETFETPGVEVTAGPLGAGISNAVGLAIAESHLAAKFNKPDFSLVDHFTYVIMG
DGCNQEGVASEACSLAGHLKLGKLIALYDDNHITIDGKTDVSFTEDVLKRYESYGWHVQHVSDGNTDVDAIAKAIQQAKE
VTDKPSIIKITTTIGYGSPNKSDTAGVHGAPLGEEEAELTRQALGWSYGPFEVPQEAYDQLRQAIDKGAKSEAVWNELLE
SYRSKYPDESIEFERMLRGELPSNWDQSLPSYTPEDKGLATRKHSQICLGALGPNLPELIGGSADLTHSNYTDIQGETGS
FQAESPEKRYLHFGVREHAMAAILNGIAYHGSGLIPYGGTFLVFADYMRGSMRLSALSELGVIYVLTHDSIGVGEDGPTH
QPIETIPSLRAMPNMLVFRPGDGNETSGAYKLAIQNRTRPSALCLSRQGMPNQENSSIEKVSFGGYVLEDCEGTPELILI
GTGSELYLCVDAAKELTKQGRKVRVVSMPCVELFEEQSSSYKEEVLPSDVRKRIVVEAAETFGWHKYIGLDGDSITMSGF
GASAPGGTCMEKFGFTLENVLNTANNLLT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 7e-169 51
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-162 50