Gene Information

Name : MmarC6_0040 (MmarC6_0040)
Accession : YP_001548098.1
Strain : Methanococcus maripaludis C6
Genome accession: NC_009975
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 35335 - 38433 bp
Length : 3099 bp
Strand : +
Note : KEGG: aba:Acid345_3755 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases

DNA sequence :
ATGTCTAATTTATGTGAAGATACGATTGAACAGGGGACTCTTGAGCTTTTAGAAAGTATTGGATACGAAATAATTTCTGG
TCCTGAAATTGCGCCTGATGGCACTTCTCCAGAACGTAAAGATTATTCTGAAGTTGTACTTGTTTCTCGCCTTAGAAACG
CAATTTCAAGAATAAATCCAAATGTTCCAGAGGTTGCGAGGGAAGATGCACTTCGAAAAGTCTTGAGGCTTGAAAATCCA
AATTTACTCATGAATAACGAGAAGTTTCACGAATTTATATTTAAGGGAATTGATGTAGAATATCCAATTGATGGAAGAGT
TAAGGGAGATAAGGTTTACTTACTCGATAAAGACCCGTTAAAAAACGAATTTGTTGCAGTAAACCAGTTTACAATCATTC
AAAATAATAAAAACAGGCGGCCAGATATTGTCATATTTGTAAACGGGCTTCCGCTTTCGGTAATCGAACTTAAAAATCCT
ACAAAAGAAGATGCTACAATTTGGAGTGCTTATAACCAGATTCAAACGTATAAATCGGAAATTTCAGAACTTTTTAAGTA
TAACGAGCTTATCCTAATTTCTGATGGTACGGAATCGAGAATAGGTACGCTTTCTTCAAATAAAGAGTGGTTTTTACCGT
GGAAATCAATTGATGGAACTTCTGAAATTAATAATGGAGTAAGCCAACTAAAGATTTCAATTCTTGGAATGTTTGATAAA
ACGCGGTTTATTGACATAATAAAGAATTTTATTGTTTTTAAAAAGGATGGAAAAGACATTATAAAAGTTATTGCTGGATA
CCACCAATATTTTGCGGCAAATCGTGCAATTGAAAAAACTATTGAAGCAATTTCTGGAAATCGCCGGTGTGGTGTTGTAT
GGCATACGCAAGGGTCTGGAAAAAGTCTTACAATGGCTTTTTATGCTGGAAAACTTGCAATTACTCCAGAACTTAGAAAT
CCTACAATCGTAGTTGTAACTGATAGGAATGACCTTGATGACCAGCTCTTTGGAACGTTTGCATCATGTATTGATGTATT
AAAACAGACTCCTGTTCAGGCAAAAAATGCAGAAGACTTAAAGGAACAGTTAAAGGTTGTATCGGGTGGAGTAATCTTTA
CAACGATGCAGAAGTTTTCTGTTGATGAACTTAATGCAAAATATCCAATGCTTTCTGATCGAGAAAACATAATCGTGATG
GCTGATGAAGCACACAGGAGCCAGTACGGACTTAAAGCGAGATCTGTTGAGAAAAACGGTGAAGTTGGTATAACTTATGG
TTTTGCTAAATATTTGCGTGATGCGCTACCAAATGCTTCATTTATTGGATTTACAGGAACTCCGATAGACTTTGAAGATA
AAAGCACCCGTTCGATATTTGGTGAATATATCGATATTTACGATGTAAGACGGGCTGTTGCTGATGGTAGAACTGTAAAA
ATCTACTATGAAAGCCGTGTTGCAAAAATCGGAATTGAAAACGACGTTCTTGCTAAACTTGACGCAGAATTTGAAGAAGT
TACAGAATTTGAAGAAAATTATAAAAAAGAGAAATTAAAGGGCAAATGGGCACAGCTTGAAGCGATTGTTGGAAGCAATG
ACAGGATTTCAAAAGTTGCACAGGATATTGTCAATCACTTTGAAAAACGGGAAGAAACGCTTAGTGGAAAAGCAATTGTT
GTATGCATGAGCAGGAGAATTTGTGTTGACCTTTATGACGAAATTATTCGTTTGCGGCCTGAATGGCATAATGACGATGA
CAAACTCGGTGTTTTAAAAGTTATAATGACAGGTTCTGCGGCTGATGGCACGGAATGGCAAAAACATATCCGTTCAAAAG
GAAAACGAAAAGAGCTTGCTGAACACTTTAAAAATCCTGAAAGCGAATTTAAAATTGCGATTGTTCGTGATATGTGGCTT
ACTGGCTTTGATGTTCCGTGTTTGCATACACTTTACATCGATAAGCCTATGAAAGGGCACGGATTAATGCAGGCGATTGC
AAGGGTAAACAGGGTATTTAGAGATAAGCCTGGAGGACTTGTTGTTGACTACATCGGAATTGCACAGGATTTAAAGTATG
CGCTTATGAATTACACTTCATCTGGCGGTACTGGGAAACCAACGTATGATATAGAAGATGCAGTAAACCTCATGAAATCA
AAATACGAAGCTATGAAAGATTTCTTTTATGGCCATGACTACTCAAAATTCTTTAATGGCACAAATATTGAAAAAATGGA
TGTAATTCCAGAAACTTTAGAATTTATCCTCAATCAGCCTGACGGGAAAAAGCGGTTTGTTAAACTTGCGCTTGAACTTA
TAAAGTCATACGCTCTATCTCTGCCGCATGAAGAAGCCGTAAAAATCCGTGAGGAAGTCGCGTTCTTTACAGGGGTTAAA
GCGGCACTGTATAAAAATACGGAAATTTCAGGAAAACCAGAAGATGAACTAAACAGCGCGATAAAACAGATTGTATCGGG
TGCAGTTCGTACTGATGGAATAATCGATGTATTTGGTGAAGCAGGACTTGAAAAACCCGATATTTCGATTCTGTCTGAAC
AGTTCCTCGAAGATGTAAAAAACATGAAATATAAAAATTTAGCACTTGAAACGCTTAAAAAAATATTAAATGACGAGATA
AGGGCTAAATTTAAAAACAATCTTTTGCAGGAAAAGAAATTTTCAGAGATGATTGAAAACGCGATTAAAAGATACCACAA
TAAAGCGATAGATTCGGCGGCAGTTATTCAAGAACTCATAGCAATTGCAAAGGAGATTGAAAACGCTAAAAGAAGAGGGG
AAGAATTACATTTAACTGAAGAAGAGCTCGCATTTTACGATGCGTTATCAGACAACGATTCAGCAAAGGAAATTTTAGGA
ACAGAGATTTTAACAGAAATTGCACGAGAACTTACCGAAACATTACGGAATAGCGTATCTATTGACTGGGAAGTTAGGGA
AACTGTAAGGGCAACTTTAAGAGTTAAAATTAAAAGGTTACTTCGAAAATATGGGTATCCTCCAGACAAACAGCAGATTG
CAGCGGACCTTGTTTTAAAACAAGCTGAAACAATTTCTAAAGAATGGATTAAGGCGTAA

Protein sequence :
MSNLCEDTIEQGTLELLESIGYEIISGPEIAPDGTSPERKDYSEVVLVSRLRNAISRINPNVPEVAREDALRKVLRLENP
NLLMNNEKFHEFIFKGIDVEYPIDGRVKGDKVYLLDKDPLKNEFVAVNQFTIIQNNKNRRPDIVIFVNGLPLSVIELKNP
TKEDATIWSAYNQIQTYKSEISELFKYNELILISDGTESRIGTLSSNKEWFLPWKSIDGTSEINNGVSQLKISILGMFDK
TRFIDIIKNFIVFKKDGKDIIKVIAGYHQYFAANRAIEKTIEAISGNRRCGVVWHTQGSGKSLTMAFYAGKLAITPELRN
PTIVVVTDRNDLDDQLFGTFASCIDVLKQTPVQAKNAEDLKEQLKVVSGGVIFTTMQKFSVDELNAKYPMLSDRENIIVM
ADEAHRSQYGLKARSVEKNGEVGITYGFAKYLRDALPNASFIGFTGTPIDFEDKSTRSIFGEYIDIYDVRRAVADGRTVK
IYYESRVAKIGIENDVLAKLDAEFEEVTEFEENYKKEKLKGKWAQLEAIVGSNDRISKVAQDIVNHFEKREETLSGKAIV
VCMSRRICVDLYDEIIRLRPEWHNDDDKLGVLKVIMTGSAADGTEWQKHIRSKGKRKELAEHFKNPESEFKIAIVRDMWL
TGFDVPCLHTLYIDKPMKGHGLMQAIARVNRVFRDKPGGLVVDYIGIAQDLKYALMNYTSSGGTGKPTYDIEDAVNLMKS
KYEAMKDFFYGHDYSKFFNGTNIEKMDVIPETLEFILNQPDGKKRFVKLALELIKSYALSLPHEEAVKIREEVAFFTGVK
AALYKNTEISGKPEDELNSAIKQIVSGAVRTDGIIDVFGEAGLEKPDISILSEQFLEDVKNMKYKNLALETLKKILNDEI
RAKFKNNLLQEKKFSEMIENAIKRYHNKAIDSAAVIQELIAIAKEIENAKRRGEELHLTEEELAFYDALSDNDSAKEILG
TEILTEIARELTETLRNSVSIDWEVRETVRATLRVKIKRLLRKYGYPPDKQQIAADLVLKQAETISKEWIKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 48
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 48
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 47
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 47