Gene Information

Name : guaA (Haur_3478)
Accession : YP_001546242.1
Strain : Herpetosiphon aurantiacus DSM 785
Genome accession: NC_009972
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4381663 - 4383207 bp
Length : 1545 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACACAGAATGAAGCAATTGTGGTGCTTGATTATGGCTCACAATATAGTCAATTGATTGTGCGGCGGGTTCGTGAAGC
GGGCGTTTATAGCGAGTTAGTGCGGTTCGATGCCGACGAGGCCACGGTTGCTGCGCTCAACCCCAAAGGCATCATTCTTT
CGGGTGGGCCGAATAGCGTCTATGCCGAGGGTGCGCCGCAACTGCCAGCATGGGTTTTGGCCAGCAACCTGCCTGTGTTG
GGCATTTGCTATGGTTTGCAATTGCAGGCCCATCATTTGGGTGGCAAAGTCGAGCCTTCCAACGACCGCGAATTTGGCCA
TGCCGTGATTACCATTACCGCTGAATCGCCACTCTTAGCCGATATTCCGACCGAACATTCGGTGTGGATGAGCCACGGCG
ATCGCTTGGAAACCCTGCCTGCTGGCTGGCATCCAATCGCGATCAGCCCCAACTCGCCCTATGCCGCTGCTGCCGATGAA
GATCGACGCTGGTATGGCTTGCAATTTCACCCTGAGGTCGTGCACTCACCCTATGGCAAGCAAGTGCTGCACAATTTTCT
CTACCGCATTTGCGCATGTGCTGGCAGTTGGCAGCCTAGCCACTTTATCCAAGAGGCGGTTGAGCGAATTCAGCAGCAAG
CGCCCAGCGGCCAAGTGATTTGTGCGCTCAGCGGTGGAGTTGATTCGGCGGTAGCAGCGTTGTTGGCCCACCAAGCCATT
GTCGAACGCTTGACCTGTATTTTTGTCGATAACGGTTTGTTGCGCCGCGGCGAGGCCGAGCAAGTTTCACGCACCTTCCG
CGATCACTTCCAAATCGAATTGATTACGGTTGATGCCGCTGAAGAATTTTTGGCAGCACTGGCAGGCGTGACCGATCCTG
AGCAAAAACGCAAGATCATCGGCGAAAAATTTATTCGCATTTTCGAGCGCGAAGCCCGTAACCTCGATGACGCGGCCTAT
TTGGTACAAGGCACGCTCTATCCCGATGTGATCGAATCGACAGCGCCAGATCGCAATGTGGCAGTCAAGATCAAAACCCA
TCATAATGTTGGCGGCTTGCCCGATGATATGAAACTCAAGGTGATCGAGCCATTACGCATGCTGTTTAAGGATGAAGTGC
GGGCAGCCGGTTTGGCCTTGGGTTTGCCCGAAGATTGGGTCTGGCGACATCCCTTCCCTGGGCCAGGTTTAGCGGTGCGG
TTGCTGGGCGCAATCAGCTTTGAGCGCTTAGAAACCTTGCGCCATGCCGATGCAATTTTCCTTGAAGAATTGCGGGCAGC
AGGCTTGTATCGCGCGACGCAGCAGGCCTTTGCGGTGTTGTTGCCAGTGCAAAGTGTCGGCGTGATGGGTGATTATCGCA
CCTATGCCGATACCATTGCGATTCGTGCGGTGAGCACCGAAGATTTTATGACCGCCGATTGGGCTCGCTTGCCCTATGAA
TTGTTGGCCAAAGTCTCCAGCCGCATTGTCAACGAGGTGACGGGAGTTAATCGGGTGGTGTATGATATTTCATCAAAACC
ACCAGCCACAATCGAATGGGAATAA

Protein sequence :
MTQNEAIVVLDYGSQYSQLIVRRVREAGVYSELVRFDADEATVAALNPKGIILSGGPNSVYAEGAPQLPAWVLASNLPVL
GICYGLQLQAHHLGGKVEPSNDREFGHAVITITAESPLLADIPTEHSVWMSHGDRLETLPAGWHPIAISPNSPYAAAADE
DRRWYGLQFHPEVVHSPYGKQVLHNFLYRICACAGSWQPSHFIQEAVERIQQQAPSGQVICALSGGVDSAVAALLAHQAI
VERLTCIFVDNGLLRRGEAEQVSRTFRDHFQIELITVDAAEEFLAALAGVTDPEQKRKIIGEKFIRIFEREARNLDDAAY
LVQGTLYPDVIESTAPDRNVAVKIKTHHNVGGLPDDMKLKVIEPLRMLFKDEVRAAGLALGLPEDWVWRHPFPGPGLAVR
LLGAISFERLETLRHADAIFLEELRAAGLYRATQQAFAVLLPVQSVGVMGDYRTYADTIAIRAVSTEDFMTADWARLPYE
LLAKVSSRIVNEVTGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-142 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-142 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-142 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-125 53