Gene Information

Name : Haur_1803 (Haur_1803)
Accession : YP_001544574.1
Strain : Herpetosiphon aurantiacus DSM 785
Genome accession: NC_009972
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2092256 - 2093884 bp
Length : 1629 bp
Strand : +
Note : TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_3645 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGGCTGAGCTGACGCTTGGCCTTGAAGGCACAACTGCTTGGCCCGCCGAGTTTGCCGAACGCTATCGTAAGGCTGGCTA
TTGGGTTGATCAGACCTTTGGCGAAGCACTACGCGAGTGGGCGCAACGCTCGGGCGATGCCACCGCTGTGGTATGTGGTG
AACGCCGTTGGAGCTACCGCGAGCTTGATCAACGGGTTGATCGCTTGGCAGCGGGCTTGCAACAGCTCGGCATCCAAACA
AAACAACGGGTGGTGGTGCAATTGCCCAATTGCGCCGAATGGTTTGTGGTTTGTTTTGCACTCTTTCGGGTTGGTGCAAT
TCCGTTGATGGCACTGCCCGCCCATCGCTTGGCTGAAATTGGCTATTTTTGCCAACACAGCGAAGCCGTGGCCTATGTGA
TTGCCGATAAAGTTGGCAGTTTCGATTATCGCAATTTGGCAGCTGAGGTCAAAGCGGTTGCGCCAACCTTGGAACATGTG
TTGGTGGTTGGTGAGGCTGGGCCGTTTACTGCTTTGGCTGAGGTCGATGCTGAGCCAAGCGAATTTCCAACGCTTGACCC
TGCCGAGGTGGCTTTGTTCCAGCTTTCGGGCGGTAGCACGGGCGTGCCCAAATTGATTGCCCGCACCCACGACGATTATT
TGTATTCGGTGCGAGCGAGTGCTGAAATCTGCAAGTTGGATGCCAGCAGCGTGTATTTGTGCGTCTTGCCGATGGCTCAT
AACTTTCCGATGAGTTCGCCTGGAACATTGGGAACTTTGGCGGCGGGCGGCACGGTGGTGCTTGCGCCGCAACCAAGCCC
CGATGTGGCTTTTCCCTTGATTGCTCGCGAAGGTGTGACGATTACTGGCATGGTTCCGCCGCTGGCATTGCTGTGGCTCG
ATGCTGCGGCAAATCGCAAGGCCGAATTATCAAGCCTCAAGCAAATTTTGGTTGGTGGTGCGCCCTTTGGTGCTTATACC
GCCCGCCGCGTGCAGCCAGAGCTTGGTTGCCAATTGCAACAAGTCTATGGTATGGCTGAGGGCTTGGTTAATTACACACG
GCTTGATGATGCGGCTGAGCTGATTTGCCACACCCAAGGCCGACCAATTTCGCCCTTGGATGAGGTACGGATTGTCGATG
ATGAAGATAATGATGTGCCGTTGGGCGAGCTTGGTCACCTGATTACCCGTGGCCCCTACACGATTCGCGGCTATTATCGC
GCTGCTGAACATAATCAACGGGCTTTTACCAGCGACGGTTTTTATCGGACTGGTGATTTGGCACGCTTGAACGCCACTGG
CTATGTTTCAGTCGAAGGCCGCGCCAAAGATCAAATCAATCGTGGTGGCGAAAAAGTCGCTGCCGAAGAAATCGAGCAAC
ATTTGCTCAATCACCCAGCGATTCACGATGTGGCGCTGGTGGGCTTGCCCGACCGATTTTTGGGCGAACGCACTTGTGCG
GTGATTGTCAGCAACGGTGTGAATATCAACCGCCGCGAAGTGTTGCAATTTTTGCGCAGCCGTGGGCTTGCCGAATACAA
ATTGCCAGATCGGGTTGAAATCGTGGAGAGTTTGCCCAAAACTGGGGTTGGCAAGATCAACAAACGGCTGTTACGTGAGC
AATTAAGTGCTGGTCGTGTGCCAGCCTAG

Protein sequence : 
MAELTLGLEGTTAWPAEFAERYRKAGYWVDQTFGEALREWAQRSGDATAVVCGERRWSYRELDQRVDRLAAGLQQLGIQT
KQRVVVQLPNCAEWFVVCFALFRVGAIPLMALPAHRLAEIGYFCQHSEAVAYVIADKVGSFDYRNLAAEVKAVAPTLEHV
LVVGEAGPFTALAEVDAEPSEFPTLDPAEVALFQLSGGSTGVPKLIARTHDDYLYSVRASAEICKLDASSVYLCVLPMAH
NFPMSSPGTLGTLAAGGTVVLAPQPSPDVAFPLIAREGVTITGMVPPLALLWLDAAANRKAELSSLKQILVGGAPFGAYT
ARRVQPELGCQLQQVYGMAEGLVNYTRLDDAAELICHTQGRPISPLDEVRIVDDEDNDVPLGELGHLITRGPYTIRGYYR
AAEHNQRAFTSDGFYRTGDLARLNATGYVSVEGRAKDQINRGGEKVAAEEIEQHLLNHPAIHDVALVGLPDRFLGERTCA
VIVSNGVNINRREVLQFLRSRGLAEYKLPDRVEIVESLPKTGVGKINKRLLREQLSAGRVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 1e-94 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-95 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 8e-95 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 9e-96 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-94 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-94 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-94 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-94 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-94 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Haur_1803 YP_001544574.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-117 52
Haur_1803 YP_001544574.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-107 48
Haur_1803 YP_001544574.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-101 48