Gene Information

Name : lysS (Haur_1675)
Accession : YP_001544446.1
Strain : Herpetosiphon aurantiacus DSM 785
Genome accession: NC_009972
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1940893 - 1942371 bp
Length : 1479 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGAATTAAACGATTTACAGCAAACACGCTATGGCAAGCTACAGGCGCTGCAAGCCGCTGGCATCGAGCCATATCCAGC
CCGAGTGCCGCAACGCACTCATACATTAACCGCCGTGCGTGAGCAATTTTCGGCCCTGGTTGAGGCCAATGCCACGGTAA
CAATTATGGGGCGCTTGCGCCAACGTCGCGTTATGGGCAAATCAGCGTTCGCCCATTTAAATGATGATCATGGCGCGTTT
CAAATTTTCCTCAGCAAAGCCGATGTTGGCGATGAGCCATTCAAGCATTTTGTTGATCTGACTGATCTTGGCGATATTAT
TGCGGTCACAGGCACGCTCTTTACGACCAAAATGGGCGAACCAAGCGTACATGTCACCAGCTGGACGATGCTCAGCAAGG
CGATCACGCCGCCACCCGACAAACGCGAAGGTCAATTTAGCGACCAAGAAGCTCGCCAACGCCAACGCTATGTTGACTTA
TCCGCCAATCCTGAAGTTCGCGAAATCTTCCGGATTCGCGCTCGTTTGATCACGGCAATGCGGCGCTACCTCGATGAACG
CGGCTTTTTGGAAGTTGAAACGCCAGTATTGCAGGGGATTTATGGTGGCGCAGCGGCGCGACCATTCACCACCCATCATA
ATCAATTGCACCAAGATTTATACCTGCGGATCGCCACCGAGCTCTATTTGAAGCGCTTGATCGTTGGCGGCTTCGATGGT
GTGTATGAAATTGGCAAAAACTTCCGCAACGAAGGCGTTGATCGCACCCATAACCCCGAATTTACCATGATCGAGGTCTA
TCAAGCCTACGGCGATTATGAATCGATTATGCAATTAACCGAGGGCATGATTCGCTTCGCTGCTGAGCAAATTTTTAACA
GCACCAGCATCGAATACCAAGGGCATCAGATCGAGCTTGGCGGTTCGTGGCAGCGCTTGACCATGCGCGATGCCATTTTT
GAAAAAACCGGGGTTGATATTCGCGAGTGCCGCGAATTTGATACACTATGGGAAGCAATTGGCGAAGCTGGCCTGAAAAT
TGAGCGCAAGCCAACCTGGGCCAAGCAAGTTGATGAGCTATTTAGTGAGTTTGTTGAGCCTGAGTTGATTCAGCCAACCT
TTATCACCGAATACCCTCAGCCACTTTCGCCTTTGGCCAAGCGCAAAGCCGATGATCCACAGTTTGTCGAGCGCTTTGAG
CTATTTATGCTTGGAGCCGAAATTGCCAACGCCTTCAGCGAATTAAACGATCCCTTCGATCAAGAGCAACGCTTCTTGGA
GCAAGGCCGCGATTATGCTGCTGGCGATGACGAAGCCATGCAAATGGACGAAGATTACCTTGAGGCGCTTAAAGTTGGTA
TGCCACCAACTGGCGGTTTAGGCATCGGGATCGATCGGCTATGTCTGTTATTTACCAATCAAACTACGATTCGTGAAGTA
ATCTTCTTCCCGCATTTGCGCAAGCAGGGCGAGGAGTAG

Protein sequence :
MELNDLQQTRYGKLQALQAAGIEPYPARVPQRTHTLTAVREQFSALVEANATVTIMGRLRQRRVMGKSAFAHLNDDHGAF
QIFLSKADVGDEPFKHFVDLTDLGDIIAVTGTLFTTKMGEPSVHVTSWTMLSKAITPPPDKREGQFSDQEARQRQRYVDL
SANPEVREIFRIRARLITAMRRYLDERGFLEVETPVLQGIYGGAAARPFTTHHNQLHQDLYLRIATELYLKRLIVGGFDG
VYEIGKNFRNEGVDRTHNPEFTMIEVYQAYGDYESIMQLTEGMIRFAAEQIFNSTSIEYQGHQIELGGSWQRLTMRDAIF
EKTGVDIRECREFDTLWEAIGEAGLKIERKPTWAKQVDELFSEFVEPELIQPTFITEYPQPLSPLAKRKADDPQFVERFE
LFMLGAEIANAFSELNDPFDQEQRFLEQGRDYAAGDDEAMQMDEDYLEALKVGMPPTGGLGIGIDRLCLLFTNQTTIREV
IFFPHLRKQGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-99 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001544446.1 lysyl-tRNA synthetase VFG1668 Protein 6e-100 46