Gene Information

Name : Sare_0863 (Sare_0863)
Accession : YP_001535772.1
Strain : Salinispora arenicola CNS-205
Genome accession: NC_009953
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 965375 - 966517 bp
Length : 1143 bp
Strand : +
Note : PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: stp:Strop_0920 cystathionine gamma-synthase

DNA sequence :
ATGAGTAACGGCTTTGAGACGCTCGCCATCCACGCCGGTCAGGATCCGGAGGCCCGTACCGGTGCGGTGATCCCACCGAT
CTACCAGACCAGCACGTACGCGCAGGACGCCGTTGGGGCGCCGCGCCAGGGCTACGAGTACAGCCGCTCCGGCAACCCGA
CCCGGGACGCCCTGCAGGAGTGCCTGGCCGCGCTGGAAGGCGGTGCCGTCGGGCTCGCCTTCGCCAGCGGACTCGCCGCC
GAGGACACGCTGTTGCGGGCAGTCTGCAAGCCCGGGGACCACGTCGTCATCCCGGACGATGCCTACGGCGGCACCTATCG
GCTCTTCGCCCGGGTCACCGAGCGCTGGGGTCTCACCTACACCCCGGCCCGGGTCTCCGACCCCGACTCGGTGCGGGCCG
CGATCCGGCCGGGGGTGACGAAGATCGTATGGGTGGAGACTCCCACCAACCCGTTACTCGGCATCGCTGACATCGCCGCC
CTCGCGGCGATCGCCCACGAGGCGGACGCGCTGCTGGTCGTGGACAACACCTTCGCCTCCCCGTACCTGCAGCAGCCGAT
CGCGTTCGGTGCGGACGTCGTCGTGCACTCGACGACCAAGTACATCGGCGGGCACTCCGATGTTGTTGGTGGTGCGCTGG
TCGTCGCCGATCCCGGCCTCGGCGCGGACCTGGGCTACCACCAGAACGCGATGGGTGCGATCAACGGGCCGTTCGACGCC
TGGCTCACCCTGCGCGGCATCAAGACCCTCGGTGTGCGGATGGATCGGCACTGTGACAACGCCGAGCGGATCGCCACGTA
TCTGGAGGGACACCCGAAGGTCGCCGGGGTCAGCTACCCGGGCCTGCCCTCCCACCCGGGGTACGAGGTGGCCGTGAAGC
AGATGCGTCGGTTCGGTGGGATGGTGTCCTTCCGCGCGACCGGCGGCGAGGAGCACGCCGTGCAGATCTGTAACCGGGCG
AAACTGTTCGTGCTCGCCGAGTCACTCGGCGGGGTGGAGTCCCTGATCGAGCACCCGGGTCGGATGACACACGCCGGTGC
TGCCGGCTCGCCGCTTGAAGTTCCCGGCGATCTCGTGCGACTGTCTGTCGGCATTGAGACGGTAGACGACCTGCTGGCTG
ATCTGGAGCAGGCGCTGGGCTGA

Protein sequence :
MSNGFETLAIHAGQDPEARTGAVIPPIYQTSTYAQDAVGAPRQGYEYSRSGNPTRDALQECLAALEGGAVGLAFASGLAA
EDTLLRAVCKPGDHVVIPDDAYGGTYRLFARVTERWGLTYTPARVSDPDSVRAAIRPGVTKIVWVETPTNPLLGIADIAA
LAAIAHEADALLVVDNTFASPYLQQPIAFGADVVVHSTTKYIGGHSDVVGGALVVADPGLGADLGYHQNAMGAINGPFDA
WLTLRGIKTLGVRMDRHCDNAERIATYLEGHPKVAGVSYPGLPSHPGYEVAVKQMRRFGGMVSFRATGGEEHAVQICNRA
KLFVLAESLGGVESLIEHPGRMTHAGAAGSPLEVPGDLVRLSVGIETVDDLLADLEQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-59 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-60 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-52 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sare_0863 YP_001535772.1 cystathionine gamma-synthase BAC0207 Protein 1e-54 43