Gene Information

Name : guaA (Sare_4223)
Accession : YP_001538995.1
Strain : Salinispora arenicola CNS-205
Genome accession: NC_009953
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4792893 - 4794446 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCACGCCGCGCCCCGTCCTGGTGGTGGACTTCGGAGCCCAGTACGCCCAGCTCATCGCGCGCCGGGTGCGGGAGGC
CCGGGTCTACTCGGAGATCGTCCCGCATTCGATGCCGGTGGCCGAGATGCTGGCGAAGGACCCGGCAGCGATCATTCTCT
CCGGCGGCCCGTCCAGCGTTTACGTGCCGAATGCGCCGCAGGTCGACGCCGGGGTGTTCGAGGCCGGTGTGCCAGTCTTC
GGTATCTGTTACGGCTTCCAGGCGATGGCCCGGGCCCTTGGGGGCACGGTCGCAAGGACCGGCAACCGGGAGTACGGGGG
TACCCCGCTGCGTCCGCGGCCGGATCCCGGGGCGTTGCTCCGTGACCTTCCCGGTGACCTGCCGGTCTGGATGAGCCACG
GCGACTGTGTGACGGAGGCGCCGCCCGGTTTCGTGGTGACCGCCGAGTCGGCGGGGGCTCCGGTGGCAGCCTTCGAGGAC
CCAACCGGGCGGCGGGCCGGGGTGCAGTTCCATCCGGAGGTCGGGCACACGGCGCACGGCCAGGAGATGCTGACCCGTTT
CCTCTACGACATCGCCGGCATCGAGCCCACCTGGACGCCGGAGAACATCATCGACGAGCAGGTGGCGCGGATCCGTGAGC
AGGTCGGCACCAAGGAGGTCATCTGTGGCCTGAGTGGTGGTGTCGACTCCGCGGTCGCCGCGGCGCTGGTGCACCGGGCC
GTCGGTGACCAACTGACCTGCGTTTTTGTTGACCATGGTCTGCTCCGGGCGGGTGAGGCCGAGCAGGTGGAGAAGGACTA
CGTTGCCGCCACCGGAATCAGGCTGAAGGTGGTCGACTCAGCTGACCGTTTCCTGACGGCCCTGGCCGGCGTGTCCGATC
CCGAGCGGAAGCGCAAGATCATCGGCCGGGAGTTCATTCGGACCTTCGAGGCCGCAGCCCGGGACATCGCCGCGCACGGT
GATGTGGAGTTCCTGGTCCAGGGCACCCTCTACCCGGATGTGGTGGAGTCCGGTGGCGGTGCGGGCACCGCCAGCATCAA
GAGCCACCACAATGTCGGCGGACTTCCGGAGGACCTCGGGTTCTCCCTGGTCGAACCGCTTCGCACGCTCTTCAAGGACG
AGGTCCGCGCGCTCGGCCTTCAACTCGGCCTGCCGGAGGCGATGGTCTGGCGGCACCCGTTCCCCGGGCCGGGGCTCGCC
ATCCGGATCATCGGGGCGGTCGACCGGGAGCGGCTCGACGTGCTCCGCCGGGCCGACTTCATCGCTCGGCAGGAACTCAG
CGCCGCCGGTCTGGACCGTGGTGTGTGGCAGTTCCCGGTGGTTCTCCTGGCGGACGTGCGCAGCGTGGGTGTGCAGGGTG
ACGGGCGCAGCTACGGGCACCCGGTGGTCCTGCGTCCGGTTTCCAGTGAGGACGCGATGACGGCCGACTGGTCGCGGCTG
CCGTACGACCTGATCGCTCGGATCTCCACTCGGATCACGAATGAGGTCGCCGAGGTGAACCGGGTGGTTCTGGACGTGAC
CAGCAAGCCGCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MSTPRPVLVVDFGAQYAQLIARRVREARVYSEIVPHSMPVAEMLAKDPAAIILSGGPSSVYVPNAPQVDAGVFEAGVPVF
GICYGFQAMARALGGTVARTGNREYGGTPLRPRPDPGALLRDLPGDLPVWMSHGDCVTEAPPGFVVTAESAGAPVAAFED
PTGRRAGVQFHPEVGHTAHGQEMLTRFLYDIAGIEPTWTPENIIDEQVARIREQVGTKEVICGLSGGVDSAVAAALVHRA
VGDQLTCVFVDHGLLRAGEAEQVEKDYVAATGIRLKVVDSADRFLTALAGVSDPERKRKIIGREFIRTFEAAARDIAAHG
DVEFLVQGTLYPDVVESGGGAGTASIKSHHNVGGLPEDLGFSLVEPLRTLFKDEVRALGLQLGLPEAMVWRHPFPGPGLA
IRIIGAVDRERLDVLRRADFIARQELSAAGLDRGVWQFPVVLLADVRSVGVQGDGRSYGHPVVLRPVSSEDAMTADWSRL
PYDLIARISTRITNEVAEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-173 71
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-135 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-135 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-135 51