Gene Information

Name : leuS (Sare_3451)
Accession : YP_001538244.1
Strain : Salinispora arenicola CNS-205
Genome accession: NC_009953
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 3978645 - 3981503 bp
Length : 2859 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTGAGGCAGCCGCCAGCGACATCCCTCCGTTCCGGTACACGGCGGCCCTGGCCGACGAGATCGAGCGTCGTTGGCA
GGACATCTGGGAACGTGAGGGCACCTTCCACGCCCCCAACCCGACCGGTCCGTTGGCCGACCCCGAGCACCCGCGGGCGG
GGGCGGAGAAGCTGTACGTACTGGACATGTTTCCGTACCCGTCGGGCGCCGGCCTGCACGTCGGGCACCCGCTGGGCTAC
ATCGGCACCGACTGCTTCGCCCGCTACCAGCGGATGGCTGGGCGCAACGTGCTGCACGCCATGGGGTTCGACGCCTTCGG
CCTGCCCGCCGAGCAGTACGCGGTGCAGACCGGCACCCACCCGCGTACCACCACCGAGGCGAACATCGCCCGATACAAGG
CGCAGCTGCGCCGGCTGGGGCTGGCCCACGACGAGCGCCGCTCGGTGGCCACCATCGACGCCGACTTCTACCGCTGGACC
CAATGGGTCTTCCTGCAGATCTACAACGCCTGGTATGACCGCGAGGCGAAGCGGGCCCGCCCGATCGCCGAGCTGATCGC
CGAGTTCTCCGGCGGTGTCCGGCGTACCCCGGACGGCCGACCCTGGCGTGAGCTGACCGACGTCGAGCGGCGGAGCGTCG
TCGACGAGTACCGGCTGGCGTACGTGTCGCAGGCCCCGGTCAACTGGTGCCCGGGGCTGGGCACCGTGCTGGCCAACGAG
GAGGTCACCGCCGATGGTCGCTCCGAGCGGGGGAACTTCCCGGTCTTCAAGCGGAACCTGAAGCAGTGGATGATGCGGAT
CACCGCGTACGGTGACCGGCTGCTGGACGACCTGGACAAGCTGGACTGGCCCGAGCCGATCAAGCTGATGCAGCGCAACT
GGATCGGCCGCTCCATCGGTGCGCACATCGAATTTCCCACCTCGGCCGGGGACTCCAGTGCGGTGGGCGAGCCGCGGATC
AACGTTTTCACCACCCGACCGGACACGATCTTCGGCGCCACCTACCTGGTGCTGGCCCCCGAGCACGCCCTGGTGGACGA
CCTGGTGCCGACGGCCTGGCCGTCGGGGACCAGGGATGCCTGGACGGGCGGGCAGGCGAGCCCACGGGCTGCGGTGGCGG
GCTACCGCAAGGTGGCCGCGGCAAAGACCGACATGGAGCGACAGGCCGAGACGAAGGAGAAGACCGGCGTCTTCATCGGG
GCGTACGCCACCAACCCGGTCACCGGGGCCCAGATCCCGATCTTCATCGCCGACTACGTGCTGGCCGGCTACGGCACCGG
CGCGATCATGGCGGTGCCCGGTCAGGACGAGCGGGACTGGGCCTTCGCCGAGGTGTTCGACCTGCCCATCGTTCGTACCG
TCAGGCCGGCGGAGGGCTTCGACGGCAAGGCGTACACCGGTGAGGGTCCGGCCATCAACAGCGCCGCCCCCGAACGCGGC
CTGAACCTGGACGGCCTGGGAGTCGCCGAGGCCAAGGCCCGGACCACCGCCTGGCTGGAGGCCAGTGGCCACGGCTCGGG
CGCGGTGACCTACCGGTTGCGGGACTGGCTGTTCAGCCGGCAGCGGTACTGGGGCGAGCCGTTCCCGATCGTGTACGACG
AGACCGGCGCCGCCATCGCCCTGCCGGAGGACATGCTGCCGGTCGAGCTACCCGAGGTGGATGACTTCTCGCCGCGCACC
TTCGATCCCGCGGATGCGGGGTCGAATCCGGAGACGCCGCTGTCGCGACGTCGGGACTGGGTCGAGGTGGAGCTGGACCT
GGGCGACGGTCCGAAGCGCTACACCCGGGAGACCAACGTGATGCCGCAGTGGGCCGGCTCCTGCTGGTACGAGCTGCGCT
ACCTGGACCCGACCAACGCCGACCGCTTCGTCGACCCGGACACGGAGCGGTACTGGATGGGCCCGCGTGGCGAGGGTGAC
TGCGGGGGAACCGACCTGTACGTCGGTGGCGCGGAGCATGCCGTACTGCATCTGCTGTATGCCCGGTTCTGGCACAAGGT
GCTGTACGACCTGGGGCACGTGTCGAGCTTCGAGCCGTTCCGGAAGCTGTTCAACCAGGGCTACATCCAGGCGTACGCGT
ACACCGACGCGCGCGGGGCGTACGTGCCGGCGGAGGAGGTTGTCGAGCGTTCCGGCGCCTACTACCTGGGCGACGTCGAG
GTCAGCCGCGAGTACGGCAAGATGGGCAAGTCCCTGCGGAACGTGGTGACGCCGGACGAGATGTGCGCCGCGTACGGGGC
GGACACGTTCCGGGTGTACGAGATGTCGATGGGCCCGCTGGAGGTTTCTCGTCCCTGGGAGACGCGGGCCGTGGTCGGGT
CGTTCCGGTTCCTGCAGCGAGTGTGGCGGGCGATCGTGGACGAGCGGAGCGGTGCGTCCCGGGTGGTGGACGCCCCGGCC
GACGAGGCGACCCGCCGGCTGCTGCACCGGATCGTGGACGGGGTTCGGGGCGACATGGAAGCGATGCGCTTCAACACCTC
GGTCGCAAAGCTGATCGAGCTGACCAACGCGCTCACCAGGCTGCCGGCGACGCCGCGTGAGGTGGCCGAGCCGCTGGTGC
TGATGGTGGCGCCGTTCGCTCCGCACGTCGCCGAGGAACTGTGGCGCCGGATGGGCCATCCGACGTCGCTGGCCTACGCC
GACTTCCCGGTTGCCGACCCGGACCTGCTGGTGGCCGAGTCGGTGACGTACCCGGTGCAGGTCAACGGAAAGGTGCGCGG
CCGGGTGCAGGTGCCCGCGGACGCCAGCGAGGAGGTCGTGCGCGCCGCCGCGTTGGATGCGGTGGCGACCGCCCTGGAGG
GCCGGGAACCTCGCAAGGTCATCGTCGTTCCCGGCCGGATGGTCTCCGTGGTCCGCTGA

Protein sequence :
MTEAAASDIPPFRYTAALADEIERRWQDIWEREGTFHAPNPTGPLADPEHPRAGAEKLYVLDMFPYPSGAGLHVGHPLGY
IGTDCFARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIARYKAQLRRLGLAHDERRSVATIDADFYRWT
QWVFLQIYNAWYDREAKRARPIAELIAEFSGGVRRTPDGRPWRELTDVERRSVVDEYRLAYVSQAPVNWCPGLGTVLANE
EVTADGRSERGNFPVFKRNLKQWMMRITAYGDRLLDDLDKLDWPEPIKLMQRNWIGRSIGAHIEFPTSAGDSSAVGEPRI
NVFTTRPDTIFGATYLVLAPEHALVDDLVPTAWPSGTRDAWTGGQASPRAAVAGYRKVAAAKTDMERQAETKEKTGVFIG
AYATNPVTGAQIPIFIADYVLAGYGTGAIMAVPGQDERDWAFAEVFDLPIVRTVRPAEGFDGKAYTGEGPAINSAAPERG
LNLDGLGVAEAKARTTAWLEASGHGSGAVTYRLRDWLFSRQRYWGEPFPIVYDETGAAIALPEDMLPVELPEVDDFSPRT
FDPADAGSNPETPLSRRRDWVEVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTNADRFVDPDTERYWMGPRGEGD
CGGTDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRKLFNQGYIQAYAYTDARGAYVPAEEVVERSGAYYLGDVE
VSREYGKMGKSLRNVVTPDEMCAAYGADTFRVYEMSMGPLEVSRPWETRAVVGSFRFLQRVWRAIVDERSGASRVVDAPA
DEATRRLLHRIVDGVRGDMEAMRFNTSVAKLIELTNALTRLPATPREVAEPLVLMVAPFAPHVAEELWRRMGHPTSLAYA
DFPVADPDLLVAESVTYPVQVNGKVRGRVQVPADASEEVVRAAALDAVATALEGREPRKVIVVPGRMVSVVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-137 46