Gene Information

Name : guaA (Dshi_1587)
Accession : YP_001532930.1
Strain : Dinoroseobacter shibae DFL 12
Genome accession: NC_009952
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1653185 - 1654747 bp
Length : 1563 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAATTCGACCATGACCGCCTCCTCATCATCGATTTCGGCAGCCAGGTGACGCAGCTGATCGCGCGCCGCTTGCG
CGAGTTGAACGTGTTTTGCGAAATCCATCCGTTCCAGAATGTAACCGATGCGTTTCTCGCCGATTTCGCGCCCAAGGCGG
TGATCTTCTCGGGTGGGCCCGCCAGCGTGATCGATGCGAATTCTCCCCGCCCGCCGGCCAGCGTTTTCGAGCTTGGCGTG
CCGATTCTCGGCATCTGTTACGGCCAGCAGGTGATGATGCAGATGCTCGGCGGCATGGTGGAGCGCGGCCATGGCACCGC
GGAATTCGGGCGCGCCTATGTCACGCCGCAGGGTGATCGGCCGGAGTTGCTCAATGGCTGGTTCCTCGATGGGCGGGAGC
AGGTCTGGATGAGCCATGGCGACCATGTCAGTCGAATCGCGCCGGGCTTCGAGGTGTACGGCACGTCGCCCAACGCCCCC
TTCGCGATCACTGCCGATCTCGCCCGCAATTTCTTTGCCGTGCAGTTTCACCCGGAAGTGCATCACACCCCGAACGGCAA
GACGCTCTACGAGAATTTCGTGCGCCTGGCCGGTTTCACCGGCGACTGGACCATGGACGCCTACCGCGAGCAGGCGATTG
CCGAAATCCGCGCGCAAGTCGGAGATGGCAAGGTGATCTGCGCGCTCTCGGGCGGTGTCGACAGCTCGGTAGCAGCGGTG
CTGATCCATGAGGCGATCGGCGAACAGCTGACCTGTGTCTTCGTGGATCATGGCCTCTTGCGCAAGAACGAGGCGCAGGA
AGTCGTCACCATGTTTCGGGAGCATTACAACCTGCCCCTGATCCATGCGGACGAGACGGAATTGTTCCTGTCGGCGCTCG
ACGGGCAATCGGACCCCGAGACCAAGCGCAAGATCATCGGCAAGCTTTTCATCGACGTCTTCGAGGCCAAGGCCAAGGAA
ATCGGCGGCGCGGATTTTCTGGCCCAAGGCACGCTCTATCCTGACGTGATCGAAAGCGTCAGCTTTTCGGGCGGGCCGTC
GGTGACGATCAAGTCCCATCACAATGTTGGCGGTCTGCCGGAAAAGATGGGCATGAAGCTGGTCGAGCCGTTGCGCGAGC
TGTTCAAGGACGAGGTGCGGGCGCTGGGCCACGAGCTGGGGCTGCCTGCATCCTTCATCGGTCGGCACCCGTTTCCGGGG
CCGGGTCTCGCGATTCGTTGCCCCGGCGAGATCACGCGCCCCAAGCTGGAAATCCTGCGCGAAGCGGACGCGGTCTATAT
CGACCAGATCCGCAAGTATGGGCTCTATGACGAGATCTGGCAGGCCTATGTCGCGATTCTGCCGGTGCGAACGGTGGGCG
TGATGGGGGATGGACGGACCTATGATTACGCCTGCGCACTAAGGGCTGTAACCTCGGTCGATGGGATGACGGCGGACTAT
TATCCCTTCACCCATGAATTCCTTGGCGAGACGGCGACGCGGATCATCAACGAGGTGCAGGGCATCAACCGGGTGACCTA
TGACATCACCTCGAAACCCCCTGGCACCATTGAATGGGAGTGA

Protein sequence :
MTQFDHDRLLIIDFGSQVTQLIARRLRELNVFCEIHPFQNVTDAFLADFAPKAVIFSGGPASVIDANSPRPPASVFELGV
PILGICYGQQVMMQMLGGMVERGHGTAEFGRAYVTPQGDRPELLNGWFLDGREQVWMSHGDHVSRIAPGFEVYGTSPNAP
FAITADLARNFFAVQFHPEVHHTPNGKTLYENFVRLAGFTGDWTMDAYREQAIAEIRAQVGDGKVICALSGGVDSSVAAV
LIHEAIGEQLTCVFVDHGLLRKNEAQEVVTMFREHYNLPLIHADETELFLSALDGQSDPETKRKIIGKLFIDVFEAKAKE
IGGADFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPEKMGMKLVEPLRELFKDEVRALGHELGLPASFIGRHPFPG
PGLAIRCPGEITRPKLEILREADAVYIDQIRKYGLYDEIWQAYVAILPVRTVGVMGDGRTYDYACALRAVTSVDGMTADY
YPFTHEFLGETATRIINEVQGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-121 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-121 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-121 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-105 49