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Name : Dshi_1262 (Dshi_1262) Accession : YP_001532605.1 Strain : Dinoroseobacter shibae DFL 12 Genome accession: NC_009952 Putative virulence/resistance : Resistance Product : acriflavin resistance protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0841 EC number : - Position : 1309307 - 1312360 bp Length : 3054 bp Strand : - Note : RND transporters are involved in multidrug resistance, heavy metal resistance. The resistance is performed by H+ driven export of the toxic compounds. DNA sequence : TTGGACCTGGCACGTTTCGCGCTGCAAAAGCGCCTGATCTCGGCGATCTCGACCCTGCTCATCCTGATCGCGGGTTTCTA TGCCTATTCGACCCTGCCGCGCTTCGAGGACCCCGAGTTCATCATCCGGCAAGCGCAGATCATCACCCCCTACCCCGGCG CCCAAGCCGAGGAGGTGGCCGAAGAGGTCACCGATGTCATCGAGGACGCGCTGCAGCAATTGCAGGGTGTACTGGAGGTG CGTTCGGTGTCGTCGCCCGGGCTGAGCAACGTAACAGTGGAATTCACGATCCCGTCGGTGCCGGACTACACGACGCTCTA TGAACGCTTCGCGCAGATGCGCGCCAAGATCGACGACGCGCAATCCCTGTTGCCGCCCAATACCCTGCCCACGCAGGTCT ATGACGATTTCGGGGATGTCTACGCGCTCTACTTCGCGGTGGTGGGCGATGGCTACACGATCACCGACCTGCACAGATAC GCCAAACAGTTGCAAAAGCTGCTCGTGACCGTGGAGGGCGTGTCGAAGGTGGTCCTCAATGGGGTGCAGGACGAGGTCAT TTATGTCGAATTCTCGCCCGCGCGTCTGATCGAGCTTGGCCTGACCGCACAGGATGTGTCGCAACTGCTAGAGGCCGAGA ACCTCGTCGCGCCCGCCGGATCGATCCAGGCCGGGGCCACGCGGCTGGAATTGCGCCCGCAGAGCGCCATCTCTTCGACC GAGGCGATCGGGAACCTGATCATCACCAACCCGGAGACCGGCGCGCTGTTCCGGCTCGGCGACATCGCCAAGGTCACGCG CGGCCTCGTGGACCCGGCCGATCCGATGATCTTCCGCGACGGCCGACCCGCCATCGGGATCGGCATTTCCAACACCCTCG GCGGCAACGTGGTCGACATGGGGGTTGCCGTGAAGGACCGCATGGAGGCGCATATCGCCGAGCGCCCCATCGGGATGGAC GTCATTGCGATCTCCGACCAGTCGGAGTCGGTCAAGGTTTCGGTGAACAGTTTCGTGAGCAACGTGCTGGTGGCCCTCGT GATCGTGGTCGGCACGCTGATGGTGTTCATGGGGTTCCGCTCGGGGATCCTGATGGGGGGCATCCTGCTGGTAACGGTGG CGGGCACGCTCTTCGGCATGTTGCTGTACGGGCTCGACATGCAGCGGATCTCGCTGGGCGCGCTGATCATCGCGCTCGGC ATGCTGGTGGACAACGCCATCGTCGTGGTCGAAGGCACATTGGTGCGCGTGCAGAAAGGCGAGAACACCGCCGAGGCCGC CATCGCCGTGGTCAACCAGACCAAATGGCCCCTGCTGGGCGGGACCGTTGTCGGGTTTCTCGCCTTCTCGCCGATCGGGT TCTCGCCCGACAATACCGGCGAGTATGCGGGCAGCCTGTTCTGGACGATCGCGATCTCGTTGCTTTTCTCCTGGCTCGTT GCGATCTGGCTGACCCCCTATTACTGCACGCTTCTGCTCAAGCCCGGTGACGCGGACGCACCGGAACAGGCCGAAAACGG CATGCTGCGCGCTTACCGGCGCCTGCTCGACCTCGCGATCCGGTTCCGCTACGGGACCGTGGTGCTGGTGGTGGCGCTCT TTGCATCGGCGCTGGCGATGTTCAGCCAGGTGCCGCCGGGGTTCTTCCCCACCTCGACACGCGAGCAGTTCGTGATCGAC TACTTCCTGCCCGAGGGCACGGATATCTCCAAAACCCGACAGGACATCCTGGAAATCGACGCCCATGCCCGCAGCCTGGC CGGCGTGACGGGCACGAATGCCGCTGTCGGCGCCGGGCATCAGCGTTTCATGCTGATCTATCAAAGCGAGGACGCCAACA GCGCCTATGGGCAGATCCTCGTGGATGTCGAAGCCTTCGACCAGATAGATGGTCTTGTGGACGAATTGCAGGCCTGGATC GTCGCGAACTACCCTGATGCCAATACCAAGGTATGGAAATTCCAACTCGGCCCGGGGGGCGGCTCGAAGATCGAAGCCCA GTTCAGCGGCCCCGATGCGGCCACCTTGCGCGCGCTCGCGACCCGCGCCAAGGAAATCATGGCCGAGTACGGCGCAATCG CGATCAAGGATGACTGGCGCGAACAGGTCCAGATCATCCGCCCGATCATCGATGCCGAGAACGCACGGCGGCTCGGCCTG TCGCAAGCCGACATCTCCCACGCACTATACGGCCATCTCAACGGGATCACGTTGGGCGTGTACCGCGAGGCCGACGAACT GCTCGACGTGATCATGCGACCGCGGGCGGCGGACCGCAACGAGATCGGCGAATTGCGCAATGTCCAAGTCTACAGCCAGG TGGTCGGAGGCTATATCCCGATCTCGCAAGTGGTGGAGCGGTTCGAGATCGCGTTCGAGGCTGGCAACCTGCGCCGCATC GACCGGCAGCTGACGATTACCGCGCAATCGGACAATGCCCCCGGGGTGCTGTCGGGCGAACTCTTCGAGCAGTTGCGCGG TCCGATCGAGGACATCCCCCTGCCGCCCGGCTACAGCCTGAGTTGGGAGGGCGAGTATGGCTCGTCGCAGGAGGCGAACG AGGGGCTGGCCTCCACCATGCCGCTGGGGTTCGGGGCGATGGTGCTGGTCGTGATCTTCCTGTTCAACGCGGTCCGGCAG CCGCTGATCATCCTGTTGACCGTGCCCCTGGCCCTGATCGGCGTCATCTGGGGATTGGCGCTGAGCGGCACACCGCTGGA GTTCATGGCGATCCTCGGCATACTTTCCCTGACGGGGATGCTGATCAAGAACGCGATCGTGCTGCTTGATGAGACCGACA GCCAGATCGCGGGGGGCAAGGCCCGCATGGCGGCGGTCGTCGACGCCGCCGTCAGCCGGGTGCGCCCGGTCTCGCTGGGT GTTCTGACCACGGTGCTGGGGGTGGTGCCACTGTTGTGGGATCCGTTCTTCAAGTCCCTCGCCGTGGTCATCATCTGCGG GCTGAGCTTTGCCACGATCCTGACACTGATTGTGGTGCCGACCCTCTACACGATCTTCTACCGGGTCACCGGGGACGAGA CCGGCGGCACCTGA Protein sequence : MDLARFALQKRLISAISTLLILIAGFYAYSTLPRFEDPEFIIRQAQIITPYPGAQAEEVAEEVTDVIEDALQQLQGVLEV RSVSSPGLSNVTVEFTIPSVPDYTTLYERFAQMRAKIDDAQSLLPPNTLPTQVYDDFGDVYALYFAVVGDGYTITDLHRY AKQLQKLLVTVEGVSKVVLNGVQDEVIYVEFSPARLIELGLTAQDVSQLLEAENLVAPAGSIQAGATRLELRPQSAISST EAIGNLIITNPETGALFRLGDIAKVTRGLVDPADPMIFRDGRPAIGIGISNTLGGNVVDMGVAVKDRMEAHIAERPIGMD VIAISDQSESVKVSVNSFVSNVLVALVIVVGTLMVFMGFRSGILMGGILLVTVAGTLFGMLLYGLDMQRISLGALIIALG MLVDNAIVVVEGTLVRVQKGENTAEAAIAVVNQTKWPLLGGTVVGFLAFSPIGFSPDNTGEYAGSLFWTIAISLLFSWLV AIWLTPYYCTLLLKPGDADAPEQAENGMLRAYRRLLDLAIRFRYGTVVLVVALFASALAMFSQVPPGFFPTSTREQFVID YFLPEGTDISKTRQDILEIDAHARSLAGVTGTNAAVGAGHQRFMLIYQSEDANSAYGQILVDVEAFDQIDGLVDELQAWI VANYPDANTKVWKFQLGPGGGSKIEAQFSGPDAATLRALATRAKEIMAEYGAIAIKDDWREQVQIIRPIIDAENARRLGL SQADISHALYGHLNGITLGVYREADELLDVIMRPRAADRNEIGELRNVQVYSQVVGGYIPISQVVERFEIAFEAGNLRRI DRQLTITAQSDNAPGVLSGELFEQLRGPIEDIPLPPGYSLSWEGEYGSSQEANEGLASTMPLGFGAMVLVVIFLFNAVRQ PLIILLTVPLALIGVIWGLALSGTPLEFMAILGILSLTGMLIKNAIVLLDETDSQIAGGKARMAAVVDAAVSRVRPVSLG VLTTVLGVVPLLWDPFFKSLAVVIICGLSFATILTLIVVPTLYTIFYRVTGDETGGT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0395_A1355 | YP_001217299.1 | AcrB/AcrD/AcrF family transporter | Not tested | VPI-2 | Protein | 0.0 | 49 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Dshi_1262 | YP_001532605.1 | acriflavin resistance protein | BAC0425 | Protein | 0.0 | 49 |
| Dshi_1262 | YP_001532605.1 | acriflavin resistance protein | BAC0519 | Protein | 8e-154 | 43 |
| Dshi_1262 | YP_001532605.1 | acriflavin resistance protein | BAC0428 | Protein | 8e-156 | 43 |
