Gene Information

Name : guaA (Dole_0966)
Accession : YP_001528853.1
Strain : Desulfococcus oleovorans Hxd3
Genome accession: NC_009943
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1127492 - 1129021 bp
Length : 1530 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGATTCTGATTATTGATTTTGGTTCACAGTTCAACCAGCTTATTGCCCGGCGGGTGCGGGAAAACAAGGTCTATTGCCA
GATCGAGCCCCCCACCATCACCATCAGCCGAATTCGCGCTCTGGCGCCGGAAGGCATTATCCTTTCCGGCGGCCCCTCAG
GTATCTATGAAAAGCACAGCCCAAAGGTGACAAAGGCGGTTTTCGACCTGGGCGTGCCGGTCCTGGGCATCTGCTACGGC
ATGCAGTTCATGGTGGGGGCACTGGGCGGCGCCGTGCACGCCGCGACAAAGCGGGAGTACGGGTTTGCCGAGCTGGCTGT
CAAGGCGCAGGCAAAGATATTCAAGGGGGTCGGCAAAAAGACCACCTGCTGGATGAGCCACGGCGATTCGGCCGAGACCG
TTCCCCCGGGGTTTAAGATCATCGGCTCCACGGAAAACACGAAAATCGCGGCCATTGCCGATACCCGGCGAAAGTTTTAC
GGCCTTCAGTTTCATCCGGAGGTGGCCCACACCGCCGAAGGCACCACCATGATCGCCAATTTTCTGTTTGACATCTGCAA
GTGCAGGCCCACCTGGTCCATGGCCGCCTTTGCCGAGGAGACGATTGCCGAGATTCGGGAAAGAGTGGGCGAAAAGCGGG
TGATTCTGGGCTTGAGCGGCGGCGTGGACTCGTCGGTGGCGGCACTGCTGATTCACCATGCCATTGGCAGGCAGCTGACC
TGTATTTTTGTGGACAACGGCCTTTTGCGCAAGGACGAGGCAAAAAAGTTAAAGGCCGTGTTTGCCGAAAAACTTCAACT
CAACATTCGGTTTGTCAATGCCGCGGGCCGGTTTTTAAAGGCCCTGGCCGGGGTCGCCGATCCGGAAAAAAAGCGCAAGA
TCATCGGCAAGATCTTTATGGATGTGTTTGAGGCCGAGGCCAAAAAAATCAAGGGGGCCGATTTTTTGGCCCAGGGCACC
CTTTATCCGGATGTAATCGAGTCCCAGTCGGCATTCGGCGGGCCCACGTCCATTATAAAGTCCCACCACAACGTGGGCGG
GCTGCCGGCAAAAATGAAGCTTTCGCTTATCGAGCCCCTGCGGTTTCTTTTCAAGGACGAGGTGCGCCTTTTAGGAAAAA
CCCTGGGCCTGGATGACGACATGGTCCACCGCCAGCCCTTTCCCGGTCCCGGCCTTGCCATTCGCATCATCGGCAAGGTG
GACCGGCGGCAGCTGACCCTGCTGCGGGAGGTCGACGCCATCCTGCTGGAGGAGATAAGAAAGGCCGGATACTATCGCAA
ACTGTGGCAGTCCTTTGCCGTGCTTTTGCCGTTAAAGAGTGTGGGCATCATGGGAGACAAGCGTACCTACGAAAACATCG
CGGCCATTCGGGCCGTCACCAGCGTAGACGCCATGACCGCGGACTGGGCAAGGCTGCCCCATGACCTGATGGGCCGCATC
TCCAACCGGATCATCAACGAGGTGAAGGGCGTCAACCGGGTGGTCTACGACATCAGTTCCAAACCGCCCAGCACCATTGA
ATGGGAGTAA

Protein sequence :
MILIIDFGSQFNQLIARRVRENKVYCQIEPPTITISRIRALAPEGIILSGGPSGIYEKHSPKVTKAVFDLGVPVLGICYG
MQFMVGALGGAVHAATKREYGFAELAVKAQAKIFKGVGKKTTCWMSHGDSAETVPPGFKIIGSTENTKIAAIADTRRKFY
GLQFHPEVAHTAEGTTMIANFLFDICKCRPTWSMAAFAEETIAEIRERVGEKRVILGLSGGVDSSVAALLIHHAIGRQLT
CIFVDNGLLRKDEAKKLKAVFAEKLQLNIRFVNAAGRFLKALAGVADPEKKRKIIGKIFMDVFEAEAKKIKGADFLAQGT
LYPDVIESQSAFGGPTSIIKSHHNVGGLPAKMKLSLIEPLRFLFKDEVRLLGKTLGLDDDMVHRQPFPGPGLAIRIIGKV
DRRQLTLLREVDAILLEEIRKAGYYRKLWQSFAVLLPLKSVGIMGDKRTYENIAAIRAVTSVDAMTADWARLPHDLMGRI
SNRIINEVKGVNRVVYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-137 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-138 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-118 48