Gene Information

Name : guaA (AZC_3705)
Accession : YP_001526621.1
Strain : Azorhizobium caulinodans ORS 571
Genome accession: NC_009937
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4250073 - 4251620 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACGACACCGTCCTCATCATCGATTTCGGCAGCCAGGTCACGCAGCTGATCGCGCGCCGGGTGCGCGAGGAAGGCGT
CTATTCGGAAGTCGTGCCCTTCCAGAAGGCCGCCGAGGCCATGGATCGGCTGAAGCCCCGCGCCGTCATCCTCTCCGGCG
GCCCGGCTTCCGTGATCGAGGGCGAGAGCCCGCGCGCCCCGCAGGCGGTGTTCGAGGCCGGCATTCCGGTGCTCGGCATC
TGCTATGGCGAGCAGGCCATGGCCGACCAGCTCGGCGGCAAGGTGGAAGCCGGGCACCATCGCGAATTCGGCCGCGCCGA
GGTGGAAGTGGTGAAGCCCGCCGCCCTGTTCGAGGGCGTGTGGCAGGAAGGCCAGCGCTATCTCGTCTGGATGAGCCATG
GCGACCGCGTCACCCAGCTGCCCGCCGGCTTCGAGGTGATCGCCCAGTCCGAGAACGCGCCGTTTGCCGCCATCGCGGAC
GAGAGCCGCAAGTTCTACGGCGTGCAGTTCCACCCCGAGGTGGTACACACGCCGCAAGGCGCCCAGCTGCTGCGCAATTT
CGTGCGCAAGGTGGCCGGCCTCCAGGGCGATTGGACCATGGGCGCCTTCCGCGAGGAATCCATCCGGAAGATCCGCGCCC
AGGTGGGCGACAAGCGCGTGCTCTGCGGCCTCTCCGGCGGCGTCGATTCCGCCGTGGCGGCGGTGCTCATCCACGAGGCC
ATCGGCGACCAGCTGACCTGCGTGTTCGTGGACCACGGCCTGATGCGCCTCGGCGAGGCCGAGCAGGTGGTCTCGCTCTT
CCGCAACACCTACAACATCCCGCTGGTGCACGTGGATGCGTCCGAGCTGTTCCTGAAGGAACTGGACGGCGTTTCGGACC
CCGAGAAGAAGCGCAAGACCATCGGCAAGCTCTTCATCGACGTGTTCGAGGCCGAGGCCAAGAAGATCGGTGGCGCCGAT
TTCCTCGCCCAGGGTACGCTCTATCCGGACGTGATCGAGAGCGTCTCCTTCACCGGCGGCCCCTCCGTCACCATCAAGTC
GCACCACAATGTGGGCGGTCTTCCTGAGCGTATGAACATGAAGCTCGTCGAGCCGCTGCGCGAGCTGTTCAAGGACGAGG
TGCGCGCGCTCGGCCGCGAGCTCGGCCTGCCGGAGAGCTTCGTCGGCCGGCACCCCTTCCCCGGCCCTGGCCTTGCCATC
CGCTGCCCCGGCGAGATCACCCCCGAAAAGCTGGAAATCCTGCGCCAGGCGGACGCCATCTATCTGGAAGAGATCCGCGC
CGCCGGCCTCTATGACGTGATCTGGCAGGCCTTTGCCGTGCTGCTGCCGGTGCGCACCGTGGGCGTGATGGGCGACGGCC
GCACCTACGACCACGTGCTGGCCCTGCGAGCCGTCACCTCCATCGACGGCATGACGGCCGACTTCTACCCCTTCCAGATG
GACTTCCTCGGCCGCGCCGCCACCCGCATCATCAACGAGGTGCGCGGCATCAACCGCGTGGTCTACGACGTGACCTCGAA
GCCCCCGGGCACGATCGAGTGGGAATGA

Protein sequence :
MHDTVLIIDFGSQVTQLIARRVREEGVYSEVVPFQKAAEAMDRLKPRAVILSGGPASVIEGESPRAPQAVFEAGIPVLGI
CYGEQAMADQLGGKVEAGHHREFGRAEVEVVKPAALFEGVWQEGQRYLVWMSHGDRVTQLPAGFEVIAQSENAPFAAIAD
ESRKFYGVQFHPEVVHTPQGAQLLRNFVRKVAGLQGDWTMGAFREESIRKIRAQVGDKRVLCGLSGGVDSAVAAVLIHEA
IGDQLTCVFVDHGLMRLGEAEQVVSLFRNTYNIPLVHVDASELFLKELDGVSDPEKKRKTIGKLFIDVFEAEAKKIGGAD
FLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRALGRELGLPESFVGRHPFPGPGLAI
RCPGEITPEKLEILRQADAIYLEEIRAAGLYDVIWQAFAVLLPVRTVGVMGDGRTYDHVLALRAVTSIDGMTADFYPFQM
DFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 57
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 57
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 57
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-126 55