Gene Information

Name : lysS (AM1_5458)
Accession : YP_001519733.1
Strain : Acaryochloris marina MBIC11017
Genome accession: NC_009925
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 5514863 - 5516416 bp
Length : 1554 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGCTGCTGATCGGGCGTCTGAGTCACCCAACCAGGGCTCCACTTTAGAAGAAGTGAGAGCTACTCGTTTGCAAAAGGT
TGAGCAGCTCAAACAAGCAGGCTTAACCCCCTATGCCTATCGGTGGCAGTCTACCCATACTGCCCAGGCTCTACAAGAGA
AATTTGTGGATCTGGCGAATGGTGAAGAGGAGGATTTTGAGGTTGCGATCGCAGGTCGTATCCTCGCTCGCCGCGTTTTC
GGTAAACTGGCCTTCTTCAACCTCCAGGACGAAACAGGAACCATCCAGCTCTACTTGGAAAAAAAGCGGATTCAAGAGCA
GATGGGGGAGCAAGATGAGCAAGCCTTTAACCACCTCAAACAGCTCACTGACGTGGGGGACTTCATCGGGGTTCAAGGCA
CTATTAAGCGTACCGATAAAGGTGAACTCTCTGTCTATGTACAGACCTACACTGTGCTCACCAAGTCCTTATTGCCCCTA
CCTGACAAATGGCATGGCTTGACTGATATTGCCAAGCGATATCGCCAACGCTATGTAGATCTGATTGTCAATCCATCTGT
ACGGGAGACGTTTCGACGACGGGCTCAGATCACCGCCAGTATTCGCCGCTATTTAGACGAGCAGGGATTTATTGAAATTG
AAACCCCCGTCTTGAACTCCGAAGCAGGAGGTGCAGAGGCCCGTCCGTTCATCACTTACCACAACACAATGGAGATGGAT
CTGTATCTGCGGATCGCAACGGAACTGCATTTGAAGCGCCTAATTGTTGGCGGTTTTGAAAAAGTCTTTGAACTGGGACG
AGTATTTCGTAACGAAGGGATTTCCACCCGCCACAACCCAGAGTTCACGACCATCGAAGTTTACCAAGCCTATGCCGACT
ACAACGACATGATGGATTTAACGGAAGCGTTGATCTGTACTGCAGCAGAACGTTCTGTGGGCAGTTTGAAAGTGCCTTAC
CAAGGCGAAACCATCGATCTCACCTCTCCGTGGCGACGAGTGACTATGCATGATGCAGTGCAAGAGAAAACGGGGCTAGA
TTTCACCACTTTTGAGACGGTAGAAGCAGCCCAAAAAGCGGCAACGAAGGCAGGCATCACAGGGGTAGACGATTGTGAGA
GTGTGGGGCATGTTTTGAACGAAGCCTTTGAGCAAAAGGTAGAGGCGACTCTAATTCAACCCACCTTTATTCTTGACTAT
CCAGTTGAGATTTCCCCCTTAGCGAAACCCCACCGGTCGCAGTCTGGACTGGTTGAACGATTCGAACTGTTTATCGTGGG
TCGAGAGACCGCCAATAGTTTCTCAGAATTGACGGATCCAGTGGATCAGCGTCAGCGCTTAGAGGCTCAAGCTGCCCGTA
AGGAAGCAGGCGACTTGGAAGCGCACGGTGTGGATGAGGACTTCATCACTGCCTTGGAATATGGCATGCCTCCCACAGGC
GGATTAGGCATTGGTATAGATCGCTTAGCAATGCTGCTGAGTGATGCGGCCAGTATTCGCGATGTGATTGCTTTCCCCCT
CTTAAAACCTGAGAAATCTGAAGATGAAGGATAA

Protein sequence :
MAADRASESPNQGSTLEEVRATRLQKVEQLKQAGLTPYAYRWQSTHTAQALQEKFVDLANGEEEDFEVAIAGRILARRVF
GKLAFFNLQDETGTIQLYLEKKRIQEQMGEQDEQAFNHLKQLTDVGDFIGVQGTIKRTDKGELSVYVQTYTVLTKSLLPL
PDKWHGLTDIAKRYRQRYVDLIVNPSVRETFRRRAQITASIRRYLDEQGFIEIETPVLNSEAGGAEARPFITYHNTMEMD
LYLRIATELHLKRLIVGGFEKVFELGRVFRNEGISTRHNPEFTTIEVYQAYADYNDMMDLTEALICTAAERSVGSLKVPY
QGETIDLTSPWRRVTMHDAVQEKTGLDFTTFETVEAAQKAATKAGITGVDDCESVGHVLNEAFEQKVEATLIQPTFILDY
PVEISPLAKPHRSQSGLVERFELFIVGRETANSFSELTDPVDQRQRLEAQAARKEAGDLEAHGVDEDFITALEYGMPPTG
GLGIGIDRLAMLLSDAASIRDVIAFPLLKPEKSEDEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-104 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001519733.1 lysyl-tRNA synthetase VFG1668 Protein 1e-104 47