Gene Information

Name : Clos_0586 (Clos_0586)
Accession : YP_001512144.1
Strain : Alkaliphilus oremlandii OhILAs
Genome accession: NC_009922
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 648367 - 650121 bp
Length : 1755 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: tte:TTE1815 pyruvate kinase

DNA sequence :
ATGAAAAGAACGAAAATCGTATGTACCATTGGACCTGCAAGTGAAAGTAAAGAGGTTTTTAGGAAATTAGTTATGCGGGG
ACTGAATGTTGCAAGATTAAATTTTTCCCATGGTAGCCATGAAGAGCACGGTGAAAGAATTCGGGTAATCAAGGAAGTAA
GAGAAGAATTAAACGAGCCTGTAGCAATTCTATTGGATACCAAAGGACCTGAAATTAGAACGGGTAAGTTTAAAGACACG
GAAGTAGAGCTTCTGGAAGGACAAGAATTCACCATTACGACGAGAGATGTTCTTGGAGATAATACCATCTGTAATGTAAG
CTATGAAGGGCTTGCAAGAGATGTAAAGGTAGGGGACAGTATCCTAATCGACGATGGTCTAGTTGGTTTAAAAGTTCAGA
ATATCGTAGGAGATACAGATATCCAATGTATCGTTGAGAATGCAGGGATTGTAAAGAATAATAAAGGTGTCAACGTACCA
GGCGTAAAAATTAATTTACCTGCTATTACAGAAAAGGATGAATCCGATATTAAATTCGGTATCGAAATGGACATTGACTT
TATCGCAGCTTCCTTCGTTAGAAAGGCAGCAGACGTTTTAGCTATTCGAAAGATTTTAGAAGATAATAACGGAAGCCATA
TTCAGATTATTTCTAAAATAGAGAATCAAGAGGGGATGGACAATCTGGATGAAATCATTGAAGTTTCAGACGGATTGATG
GTTGCAAGGGGCGATTTGGGTGTAGAAATCCCTACGGAAGAAATTCCTTTGGCTCAAAAAGAAATGATCAGAAAATGTAA
TAGAGCTGGAAAGCCTGTTATTACAGCGACACAAATGCTGGATTCCATGATCAGAAACCCAAGACCAACTCGCGCAGAGG
TAACGGATGTTGCCAATGCTATCTTTGACGGAACCGATGCAATCATGCTTTCCGGAGAAACTGCGGCTGGGAAGTATCCA
GCAGAGGCAGTCGAGGTGATGAGCAACATTGCCAAGCGTGCAGAAGCTGCCATCGACTATAGGGGACTTCTAAAAACGAA
AGCCATAGAAATGGAAACCTCTGTGACGGATGCTATCAGCCATGCTACCTGCACAACAGCAGCAGATTTAGATGCATCTG
CCATTGTTACAGCTACATCTTCGGGATATACTACAAGAATGGTATCTAAATTTAGACCATCAGCACCGATTATTGCAACG
ACTACAAGCGAAAGTGTAAGAAGAAGATTGAGCTTAATCTGGGGGGTTTACTCTGTTATTACAGAGCAACTTCATTCCAC
AGACGATATCATTGATATCTCTGTAAGCAAGGCCCTAGAAGCGGAGCTAATTCGTAATGGAGATTTAATTGTAATCACAG
CAGGCGTTCCAGTAGGAGTTTCCGGTACGACCAACCTAATCAAAGTTCATATCGTAGGAGAAGTCATCCTATCTGGAACT
GGGATTGGAAAAAAAGCTGCCACTGGAAAGGTTGTTATTGTAAATAGTGTCGAAGATGGACATAAGGTTGAAGAAGGCGA
TATCTTAGTAGCAAAAGCAACGGACAGAGATTTAATGCCTTTCATAGAAAAAGCTGCTGCAATCATCACAGAAGAAGGCG
GCTTGACTAGCCACGGCGCTATTGTTGGATTGAACCTGGGGAAAGCAACCTTAGTTGGAGCAGATATGGCAACCATAAAG
CTAAAAGAGGGAGAAATCGTTACGGTAGATGCCTTAAGAGGCTTGGTATACAGCGGAGAAACAAAAGTTCTTTAA

Protein sequence :
MKRTKIVCTIGPASESKEVFRKLVMRGLNVARLNFSHGSHEEHGERIRVIKEVREELNEPVAILLDTKGPEIRTGKFKDT
EVELLEGQEFTITTRDVLGDNTICNVSYEGLARDVKVGDSILIDDGLVGLKVQNIVGDTDIQCIVENAGIVKNNKGVNVP
GVKINLPAITEKDESDIKFGIEMDIDFIAASFVRKAADVLAIRKILEDNNGSHIQIISKIENQEGMDNLDEIIEVSDGLM
VARGDLGVEIPTEEIPLAQKEMIRKCNRAGKPVITATQMLDSMIRNPRPTRAEVTDVANAIFDGTDAIMLSGETAAGKYP
AEAVEVMSNIAKRAEAAIDYRGLLKTKAIEMETSVTDAISHATCTTAADLDASAIVTATSSGYTTRMVSKFRPSAPIIAT
TTSESVRRRLSLIWGVYSVITEQLHSTDDIIDISVSKALEAELIRNGDLIVITAGVPVGVSGTTNLIKVHIVGEVILSGT
GIGKKAATGKVVIVNSVEDGHKVEEGDILVAKATDRDLMPFIEKAAAIITEEGGLTSHGAIVGLNLGKATLVGADMATIK
LKEGEIVTVDALRGLVYSGETKVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-96 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-96 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-96 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-96 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clos_0586 YP_001512144.1 pyruvate kinase VFG0479 Protein 4e-97 53