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Name : Clos_2860 (Clos_2860) Accession : YP_001514385.1 Strain : Alkaliphilus oremlandii OhILAs Genome accession: NC_009922 Putative virulence/resistance : Resistance Product : D-alanine--D-alanine ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : 6.3.2.4 Position : 3107266 - 3108315 bp Length : 1050 bp Strand : - Note : KEGG: cdf:CD1626 putative D-alanine:D-alanine ligase (putative vancomycin/teicoplanin A-type resistance protein); TIGRFAM: D-alanine--D-alanine ligase; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; D-alanine--D-alanine ligase doma DNA sequence : GTGGGAAAGATCGTTGTAGCTGTAATTTTTGGAGGGGAATCCTCAGAGTATGAAGTATCATTAAAATCGGCAAGTGCTGT TATGGAAAACTTAGATATAGAAAAATATGATGTAATAAAAATAGGCATTACCAGAGACGGAAAGTGGCTTCGATATAATG GCACTTTAGATAAAATCAAGGAAAACACATGGTTTTTAGATGGTAGCTGCCGACAAATCATGCTCTCTCCTAATAAGGGG GATCGAAAAATCATTGAAATCCATCCAAATGAATTTGTACACACCCAAATAGATATTGTGTTTCCTGTACTTCATGGCAG GAATGGAGAAGATGGAACGCTCCAAGGGCTGTTTGAAATCACAGGAATTCCTTATGTTGGATGTGATGTAGCAGCAAGCT CTATTTGTATCGATAAGGACTACGCTCATAAAATTGTTCAATATGCAGGCTTTGATGTCCCTCAAAGTATAGCCATAGAT AACCGAACAAAAGAAGATGAAATCAACAAGTTCGCAGAGAATGTAGGATACCCTATCTACGTTAAACCCTCTAGAGAAGG CTCTTCCATAGGTATAACGAAGGCAGAGAATCATAGTGATTTAATGGGTGGAATAGAGGCGGCACTGAAGCTGGATGGTA AAGTCGTATTAGAAGAAAATATAGAGGGATTTGAAGTGGGATGTGCCATTTTAGGGAATGACGATCTAATTGTTGGTACA GTGGATGAGATCGAAGTGCCCAATGGATTTTTTGATTTTACAGAAAAATATACCTTACAGAATTCTAAGATCCATTTACC GGCAAGGATTGATCAGGACCTCAGTGAAAGGATAAAAGAAATTGGAAAGGGGATCTATAAAGCTTTAGGATGCAGTGGTC TTTCAAGGGTGGATTTATTTGTAGACAAAAACCATAGAATTGTTTTTAACGAAGTAAATACACTACCAGGATTTACTACG GGAAGTCGATTTCCCAATATGCTGCTTCATGCAGGAATAGCCTATAGAGATATATTGGACAAGTTGATTGACTTAGGAAT GCAGAGGTAA Protein sequence : MGKIVVAVIFGGESSEYEVSLKSASAVMENLDIEKYDVIKIGITRDGKWLRYNGTLDKIKENTWFLDGSCRQIMLSPNKG DRKIIEIHPNEFVHTQIDIVFPVLHGRNGEDGTLQGLFEITGIPYVGCDVAASSICIDKDYAHKIVQYAGFDVPQSIAID NRTKEDEINKFAENVGYPIYVKPSREGSSIGITKAENHSDLMGGIEAALKLDGKVVLEENIEGFEVGCAILGNDDLIVGT VDEIEVPNGFFDFTEKYTLQNSKIHLPARIDQDLSERIKEIGKGIYKALGCSGLSRVDLFVDKNHRIVFNEVNTLPGFTT GSRFPNMLLHAGIAYRDILDKLIDLGMQR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 2e-65 | 44 |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 1e-65 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | AY145441.gene.p01 | Protein | 8e-67 | 44 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | U00456.gene.p01 | Protein | 1e-65 | 44 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | AF310956.2.orf5.gene | Protein | 2e-66 | 44 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | U35369.1.gene6.p01 | Protein | 1e-65 | 44 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | AE016830.1.gene2250. | Protein | 1e-65 | 44 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | AF277571.gene.p01 | Protein | 1e-61 | 42 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | AF130997.1.orf4.gene | Protein | 1e-61 | 41 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | NC_014475.1.orf3.gen | Protein | 2e-62 | 41 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | NC_005054.2598280.p0 | Protein | 2e-62 | 41 |
| Clos_2860 | YP_001514385.1 | D-alanine--D-alanine ligase | AY489045.gene.p01 | Protein | 2e-60 | 41 |
