Gene Information

Name : Clos_2446 (Clos_2446)
Accession : YP_001513974.1
Strain : Alkaliphilus oremlandii OhILAs
Genome accession: NC_009922
Putative virulence/resistance : Resistance
Product : 3''-adenylyltransferase
Function : -
COG functional category : R : General function prediction only
COG ID : COG1708
EC number : 2.7.7.47
Position : 2643925 - 2644758 bp
Length : 834 bp
Strand : -
Note : PFAM: DNA polymerase beta domain protein region; KEGG: dsy:DSY4374 hypothetical protein

DNA sequence :
ATGAGTGATTTGAATAAGAAAATAATACCGACGGAAGCAACTCAAGCATTAGAGGTTATAAAGGAGCTGCTTGGAAATGC
AGTAGTTGGTGTATATCTCTTTGGATCTGCCGTAGAAGGTGGATTGCGTATTCATAGCGATGTGGATGTCTTAGTGATCG
TAAATCAGAGGCTAACAGAAATAAAGCGAAGAAAATTAGTCACTAGATTCATGACGATCTCTGGGAAAATAGGAAATAAA
GATTCTGTGCGACCGCTTGAAGTTACGATTATAAATCGTGTAGATGTAGTACCTTGGCAATATCCGCCCAAAAATGAATT
GATCTATGGTGAATGGCTCAGGGACGAATTTGAGCAAGGAAAAATTCCAGAACCCGTTTATGATCCTGATTTGGCCATCG
TTTTAAATCAAGTGAGAAATAATAGCATTTCTCTTCTTGGACAAAATGCTTCAGAAATACTGGAACCCGTGCCGATGACG
GATATTCGAAGAGCGATTATGGACTCACTACCAGGATTAATTGGGAGCATAAAGGGTGACGAGTGCAACGTGATTTTAAC
TCTAGCCAGAATGTGGCTGACAGTAGCTGTCGGTGAAATTTCTCCAAAGGATGTAGCTGCAGAATGGGCTATACCCAAGC
TATCTGAAGAACAAGCAGCTGTATTGAGTTTGGCTAGAAAAGCCTATCGAGGAGAATATGTTGATGAGTGGGAAGGACTG
AGCTCCGAAGTGGCAGCAGTCGTTAATCATATGAAAAAGTCCATAGAATCTTGCTTAGGTATATGTGAGGAAAGAGGACA
AAAAAGAAGTATGGTATCTGCCAATGTAAAGTAG

Protein sequence :
MSDLNKKIIPTEATQALEVIKELLGNAVVGVYLFGSAVEGGLRIHSDVDVLVIVNQRLTEIKRRKLVTRFMTISGKIGNK
DSVRPLEVTIINRVDVVPWQYPPKNELIYGEWLRDEFEQGKIPEPVYDPDLAIVLNQVRNNSISLLGQNASEILEPVPMT
DIRRAIMDSLPGLIGSIKGDECNVILTLARMWLTVAVGEISPKDVAAEWAIPKLSEEQAAVLSLARKAYRGEYVDEWEGL
SSEVAAVVNHMKKSIESCLGICEERGQKRSMVSANVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ant(9) NP_373289.1 O-nucleotidylltransferase(9) Not tested Type-II SCCmec Protein 8e-86 68
spC YP_190051.1 streptomycin 3''-adenylyltransferase Not tested Type-II SCCmec Protein 8e-86 68
ant(9) BAC57473.1 O-nucleotidyltransferase(9) Not tested Type-IIIinv SCCmec Protein 6e-86 68
spc BAA82204.1 O-nucleotydiltransferase(9) Not tested Type-II SCCmec Protein 6e-86 68
spc1 YP_039523.1 streptomycin 3''-adenylyltransferase 1 Not tested Type-II SCCmec Protein 8e-86 68
ant(9) NP_370577.1 O-nucleotidylltransferase Not tested Type-II SCCmec Protein 8e-86 68

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002745.1124325.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002745.1125314.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase GU235985.1.orf1.gene Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_009782.5559439.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002758.1121631.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002952.2859154.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002745.1123578.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002745.1124853.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_009782.5559472.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002758.1120013.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002952.2859153.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase NC_002745.1122823.p0 Protein 3e-86 68
Clos_2446 YP_001513974.1 3''-adenylyltransferase M69221.gene.p01 Protein 1e-39 41
Clos_2446 YP_001513974.1 3''-adenylyltransferase AJ584652.2.gene7.p01 Protein 2e-41 41