Gene Information

Name : Clos_0014 (Clos_0014)
Accession : YP_001511580.1
Strain : Alkaliphilus oremlandii OhILAs
Genome accession: NC_009922
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 18900 - 20177 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATTAAGAGAATTAGAAATAACCTAGATGAAATAAAAGCAGCAATGGCAAGAAGAGGGGAAAAAGATTTTGA
TTTAGATGCAGTAGTCGCACTAGATGAAAAGAGAAGAGAATTGCTTCAACAGGTAGAACTGATGAAAAATGAGCAAAATA
CAGTTTCTAAAGAAGTTCCAAAGCTAAAAAAGGAAGGAAAAGATGCTACAGAAGTAATGGCAAGAATGAAAGAGCTTTCT
GGAAAAATTAAAGAATTAGATGGCCAAGTTAAGGAAGTGGAGGATCAGTTAGAGTATACACTACTTCGAATACCCAATGT
TCCACATCCTGATGTACCGCAGGGAGAAACAGACGATGATAACATTGAAGTAAGAAAATGGTCAGAGCCTACTCATTTTG
ATTTTGAACCCAAGGCCCATTGGGATATCGCTACGGATTTAGGAATTATCGATTTTGAAGCAGCATCAAAAATAACAGGA
GCACGATTTGCGCTATATAAAGGCGTAGGCGCAAGATTAGAGAGAGCTTTAATCAACTTCATGCTAGATCTTCATATAGA
GGAGCATGGTTATACAGAGGTTCTACCGCCATTCATGGTGAATAGAAGCAGTATGACGGGTACTGGACAATTGCCTAAAT
TTGAGGAAGATGCTTTTAAACTACCACAGAAGGATTACTTCTTAGTACCGACTGCAGAGGTTCCAGTGACAAATATGCAT
AGGGATGAGATTATAGAAGGAGCAAATCTACCTTTAAGCTACGTAGCATATACGCCTTGTTTCCGATCAGAAGCAGGATC
TGCTGGTCGAGATACGAGAGGTTTAATAAGACAACATCAGTTCAATAAAGTAGAGCTTGTGAAATTTGTTAAGCCAGAGG
ATTCCTATGCAGAGCTTGAAAAACTTACAAACAACGCAGAAAAAGTACTTCAATTACTAGAAATACCTTATCGAATCGTG
AGAATCTGCACGGGAGATTTAGGATTCACTGCTGCATTTAAATATGATATCGAGGTATGGATGCCGAGTTATAATCGATA
TGTTGAAATATCTTCTTGCAGTAACTTTGAAGACTTCCAAGCCAGAAGAGCAAATATCAGATATCGTCCTGAGGAAAAAG
GTAAAGTAGAATTCCTTCATACATTAAATGGTTCAGGTCTTGCTGTAGGTAGAACTGTAGCAGCTATTTTAGAAAACTGC
CAGGATGATGAAGGGAATGTAAAAATACCGGAAGCTTTAATCCCTTATATGAGAGGAATCAAGGTGATTACAAAATAA

Protein sequence :
MLDIKRIRNNLDEIKAAMARRGEKDFDLDAVVALDEKRRELLQQVELMKNEQNTVSKEVPKLKKEGKDATEVMARMKELS
GKIKELDGQVKEVEDQLEYTLLRIPNVPHPDVPQGETDDDNIEVRKWSEPTHFDFEPKAHWDIATDLGIIDFEAASKITG
ARFALYKGVGARLERALINFMLDLHIEEHGYTEVLPPFMVNRSSMTGTGQLPKFEEDAFKLPQKDYFLVPTAEVPVTNMH
RDEIIEGANLPLSYVAYTPCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYAELEKLTNNAEKVLQLLEIPYRIV
RICTGDLGFTAAFKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIRYRPEEKGKVEFLHTLNGSGLAVGRTVAAILENC
QDDEGNVKIPEALIPYMRGIKVITK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-122 60