Gene Information

Name : Clos_1206 (Clos_1206)
Accession : YP_001512748.1
Strain : Alkaliphilus oremlandii OhILAs
Genome accession: NC_009922
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1305207 - 1307891 bp
Length : 2685 bp
Strand : +
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAAAACGCATAGTGATTATTGATGGAAATAGTTTAATAAATAGAGCCTTCTATGCTCTTCCGCCTTTAACCAACAA
AGAGGGACAGCATACCAATGCCATATATGGATTTGTAACGATGCTATTAAAAGTGATGGAGGATTATGCACCCGATTATA
TCGGTGTAGCTTTTGATAAAAAAGCACCGACCTTTAGACATAAAGAATATACGGAGTACAAAGCTGGTAGAAAGGGAATG
CCACCAGAGCTTGCAGAGCAGCTAGAGCCTTTGAAGCAAGTATTGGATGCTTTGAATATTTATCGAATCGAATTAGAAGG
GTTTGAGGCAGACGATTTAATTGGTACATTGGCGAAGCATTGTGAAGCACAAGGCATTGAAAGTTTAATTGTAACAGGGG
ACAGAGATGCTCTGCAGCTGACATCGGATACAACGAAGGTACTCTTTACGAAAAAAGGAATATCTCAACTGGAAATCTAT
GATGCAAAAAAGGTCATGGAGGACTATGAAGTTACGCCTACCCAATTTATCGATTTAAAAGGCCTAATGGGAGATAAATC
AGATAATATTCCTGGTGTTCCAGGTGTAGGAGAAAAAACGGCGATTAAGCTTCTGAAGCAGTTTGAAACCATTGAAAATA
TGATACAGAATACCAGTGAGATCGCTGCAGATAAACTGAGACAGAAAATAGAAGAAAATATAGAAATGGCCGTACTCAGT
AAAAGATTGGCGACGATTGTTACCAACGTTCCTGTGGAAATGGACTTAGATATTCTTAGAAAGAAAGAGTTTGACTACGA
AAGACTAATTGAACTATTTAGAATGTATGAATTCAATAGTTTGATCCCTCGTATTAAGAAAAATATGGAGCAAACACAGG
AAATTAGCACAGCGAATCTAGGCAATCGTGAAAATATTGTTGCCATCAAGGATACAGATGCTCTAAAAAAAGCACTGGAA
GAAATAAGAGAACAAGGGCAAATGGTTCTCAAAACAATTACAGAGGAAAATAATATTGTAACAGACAGAATCGTTGCATT
GGCTATGACTACTACGGGAGAGATTCAATACTACATTGAGTTTAAGGATTTTAAAGAATCTGATATTATAAGTCCTTTAA
AAGACATTTTAGAGGATGAACATATTCGAATCATCGGTCATGATTTGAAAAAGGAAATCATCCATTTCTATCCCTATGAG
ATTCATATTGCAAATTTATATTTCGATACCATGGTGGGAGAATACTTATTGAACCCAGCAAAGTCAAGTTATCTTCTCAA
GGATTTAGCTTTAGAGTACTTAGGTGAAGAAATTATCGATGAGGAAAAAATCGTAGGAAAAGGTAAAAATCAGCTATCCC
TATGGGCTGCACCAGAGAATGAGGTGAAGGCCTTACTTTGTAATCATGTAAAGGTGATTGCAGAGCTTGCAAAATATATA
CAAGAAAAAATAGAAGATCAGGGGATACATAAGCTTTATTATGAGGTGGAACTTCCTTTAGTAGAAGTTCTAGCGTCCAT
GGAGTTTTTGGGAATTAAGGTGGATCGAAACATGCTATTGGCGCTGGAGGTGGAATTTAAAGAAATCATAGACAAACTAA
CCAGTGAAATTTACTCTTTAGCAGGGATATCATTTAACATCAACTCGCCAAAACAGCTGGGAGAAGTTTTGTTTGAAAAA
CTGGGATTACCGCCGACAAAGAAAACGAAAACAGGATATTCTACCAATGCGGATGTCCTTGAAAAACTACAGGACCAGCA
TGAGATTATACCGAAAATATCAGAATATCGTCAGGTTACAAAGCTAAAAACTACTTATGTAGATGGGCTTCTTAGTATTA
TTAATCCAGTGACAAATCGCATCCATTCTAGTTTTAATCAGACTGTTACAGCTACAGGCAGAATCTCAAGCACGGAGCCA
AATCTTCAAAATATTCCTGTACGTCTGGAAATGGGTAGGAGACTTCGCAAGGTATTCATATCGAAGGAAGGACATGAATT
TATCGATGCGGATTATTCTCAAATTGAGCTTAGAGTCCTTGCGCATATTGCAAAAGATGATAATTTAATCGATGCTTTTA
TTAAAAACCAAGACATTCATACGAGAACGGCATCTGAAATATTTGAAGTGCCTATGGAGGAAGTAACATCCTTGATGAGG
GGCGATGCAAAGGCGGTCAACTTCGGTATCGTCTATGGTATTAGTGATTTTGGTCTATCGCAAAATTTAAATATTCCAGT
ATCCAAGGCAAAAAAATATATTGAAAGCTATTTTGAGAAGTATCCTTCCATTAAGGAATATATGCACAATATTGTAGAGG
AAGGAAAAGAGAAAGGTTACGTTGTAACCTTATTGAATAGAAGGAGATATCTACCAGAATTAAAGTCTTCAAACTTTAAT
ATTCGCAGCTTTGGTGAGCGTATTGCTATGAATACACCAATCCAAGGAAGTGCGGCGGATATTATAAAGATCGCTATGAT
TGCAGTATACAATAGACTGAAAGCGGAAAATTATGATGCAAAATTAATTCTTCAGGTTCATGACGAATTAATCATCGAAT
GTCCTGAAAATGAGATAGAGGAAGTGTCGAAAATTCTAAAAGAGTCTATGGAGAATGCCATAGAGATGGTAGTGCCTTTA
AAGGTAGATTTGTCGTATGCAAACAATTGGTATGATGCGAAGTAA

Protein sequence :
MEKRIVIIDGNSLINRAFYALPPLTNKEGQHTNAIYGFVTMLLKVMEDYAPDYIGVAFDKKAPTFRHKEYTEYKAGRKGM
PPELAEQLEPLKQVLDALNIYRIELEGFEADDLIGTLAKHCEAQGIESLIVTGDRDALQLTSDTTKVLFTKKGISQLEIY
DAKKVMEDYEVTPTQFIDLKGLMGDKSDNIPGVPGVGEKTAIKLLKQFETIENMIQNTSEIAADKLRQKIEENIEMAVLS
KRLATIVTNVPVEMDLDILRKKEFDYERLIELFRMYEFNSLIPRIKKNMEQTQEISTANLGNRENIVAIKDTDALKKALE
EIREQGQMVLKTITEENNIVTDRIVALAMTTTGEIQYYIEFKDFKESDIISPLKDILEDEHIRIIGHDLKKEIIHFYPYE
IHIANLYFDTMVGEYLLNPAKSSYLLKDLALEYLGEEIIDEEKIVGKGKNQLSLWAAPENEVKALLCNHVKVIAELAKYI
QEKIEDQGIHKLYYEVELPLVEVLASMEFLGIKVDRNMLLALEVEFKEIIDKLTSEIYSLAGISFNINSPKQLGEVLFEK
LGLPPTKKTKTGYSTNADVLEKLQDQHEIIPKISEYRQVTKLKTTYVDGLLSIINPVTNRIHSSFNQTVTATGRISSTEP
NLQNIPVRLEMGRRLRKVFISKEGHEFIDADYSQIELRVLAHIAKDDNLIDAFIKNQDIHTRTASEIFEVPMEEVTSLMR
GDAKAVNFGIVYGISDFGLSQNLNIPVSKAKKYIESYFEKYPSIKEYMHNIVEEGKEKGYVVTLLNRRRYLPELKSSNFN
IRSFGERIAMNTPIQGSAADIIKIAMIAVYNRLKAENYDAKLILQVHDELIIECPENEIEEVSKILKESMENAIEMVVPL
KVDLSYANNWYDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 1e-149 42