Gene Information

Name : smpB (Clos_0978)
Accession : YP_001512521.1
Strain : Alkaliphilus oremlandii OhILAs
Genome accession: NC_009922
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1072550 - 1073017 bp
Length : 468 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCCAGTAAAGGAACAAAGCTAATAGCAACCAATAAAAAAGCACGACATGATTACTTTATTGAAGAAACCTTTGAAAC
AGGAATTGTTTTAGTAGGAACGGAAGTAAAGTCTATTAGACAAGGAAAATTAAATATTAAAGATGGCTATGCACGGGTTG
AAAACAGTGAGGTTTTCCTTTACAATGTTCATATTAGCCCTTATGAACAGGGAAATATTTTCAACAAAGATCCTTTAAGA
GTAAGAAAACTTTTGCTTCATAAGAGTGAAATAAGAAAGCTGATTGGATATGTTCAGCAAAAAGGATATACCCTCATCCC
CTTAAGTTTTTATTTAAAGGATGGATTGATTAAGGTTGAGCTAGGGATCGGTGTTGGTAAAAAGATTTATGACAAACGCC
AGGACATAGCGAAGAAAGATGCTGCACGTCGAATAGACAAAGAGCTGCGCCAAAGAGAGAAACAATAG

Protein sequence :
MASKGTKLIATNKKARHDYFIEETFETGIVLVGTEVKSIRQGKLNIKDGYARVENSEVFLYNVHISPYEQGNIFNKDPLR
VRKLLLHKSEIRKLIGYVQQKGYTLIPLSFYLKDGLIKVELGIGVGKKIYDKRQDIAKKDAARRIDKELRQREKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-36 57
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-33 52
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-26 43