Gene Information

Name : Franean1_7138 (Franean1_7138)
Accession : YP_001511365.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 8718698 - 8719738 bp
Length : 1041 bp
Strand : -
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sco:SCO3594 putative D-lactate dehydrogenase

DNA sequence :
ATGCCCCGCAGCGAACCCGCACGAACAGCGGCCCGCCGCACCCGGTCGCCGGCGCCCTCGTCCTCCTCAGCCGTCCCGGC
AACGGGAATCACGATCTATGGATGCGGGCAGGACGAGGCCGTTCTTTTCCGAGAGATGGCTCCCCGTTTCGGCGTACTGC
CAACCATCACAGACGTGGCGGTATCTGAAGCCAACATCGAACTGGCACTCGGAAACCGATGCATCAGCGTCGACCACAGG
ACTCGGGTCACGAGCTCCACTCTTCTTGCACTCAGCCAGGTCGGCGTGACGTACATCTCCACAAGAAGCATCGGGTGCAA
CCATATCGACGTGAAATACGCTGCGGGCGTCGGCATCTCCGTCGGAAACGTCGCCTATTCGCCCGACAGCGTGGCCGACT
ACACGCTGATGCTGATGCTGATGGTGGTGCGGAACGCAAAGTCCATCATCCGCCGCGCGGATATTCATGACTACAGACTG
AATGATGTGCGCGGGAGGGAACTACGCGATCTGACCATCGGGGTGGTTGGAACAGGACGCATCGGCGCGGCGGTCATGGA
CAGGCTGCGGGGTTTCGGCTGCCGAACACTGGCCTATGACGATCGCCCCGAGGCCGCCGCCGAATACGTTCCGCTCGACG
AATTGCTGGAACTGAGCGACATTGTGACGCTCCATACCCCCCTCAATGCGGATACACACCACCTCCTAAATCGTCGACGT
ATCGAGAGGATGAAGCGCGGCGCGTTCCTTGTCAATACCGGACGCGGCCCACTCCTTGATACCGAGGCCCTTGTTCAGGC
ATTGGAAAGCGGCAGACTGGGCGGTGCGGCGCTGGATGTCCTCGAAGGAGAGGAAGGAATATTCTACGCCGATCACAGGA
ACAAGCCCATCGAATGCGCACCGCTGCTACGGCTGCAAGAACTGCCGAATGTTCTGGTCAGTCCCCACACCGCCTACTAC
ACAGACCACGCCCTGCGTGACACCGTTGAAAACTCCATCACCAACTGCCTCGAATTCGAAAGCAGGATTCAGCATGGATA
G

Protein sequence :
MPRSEPARTAARRTRSPAPSSSSAVPATGITIYGCGQDEAVLFREMAPRFGVLPTITDVAVSEANIELALGNRCISVDHR
TRVTSSTLLALSQVGVTYISTRSIGCNHIDVKYAAGVGISVGNVAYSPDSVADYTLMLMLMVVRNAKSIIRRADIHDYRL
NDVRGRELRDLTIGVVGTGRIGAAVMDRLRGFGCRTLAYDDRPEAAAEYVPLDELLELSDIVTLHTPLNADTHHLLNRRR
IERMKRGAFLVNTGRGPLLDTEALVQALESGRLGGAALDVLEGEEGIFYADHRNKPIECAPLLRLQELPNVLVSPHTAYY
TDHALRDTVENSITNCLEFESRIQHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 8e-95 61
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 5e-93 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase AF155139.2.orf4.gene Protein 5e-102 65
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase NC_014475.1.orf2.gen Protein 1e-100 62
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase NC_005054.2598279.p0 Protein 1e-100 62
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase U35369.1.gene5.p01 Protein 3e-94 60
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase FJ349556.1.orf3.gene Protein 2e-94 60
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase AF310956.2.orf4.gene Protein 1e-93 59
Franean1_7138 YP_001511365.1 D-isomer specific 2-hydroxyacid dehydrogenase AF130997.1.orf3.gene Protein 1e-80 55