Gene Information

Name : Franean1_6425 (Franean1_6425)
Accession : YP_001510668.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 7805191 - 7806348 bp
Length : 1158 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0783 cystathionine gamma-synthase, PLP-dependent

DNA sequence :
ATGGGTGATCGGAACTCGGGATTCGAGACCGTCGCGGTGCACGCGGGCCAGGAGCCCGACCCTGCCACCGGCGCGGTCGT
CGTCCCCATCCATCCCGCGTCGACGTTCGCGCAGGACGGCGTCGGCGGGCTGCGGGCCGGCTTCGAGTACGCCCGCTCGG
GCAACCCGACCCGCGCCGCGCTGGAGGCCAGCCTGACCGCGCTCGAGCGCGGGGCCGCGGCGCTCGCGTTCGCCTCCGGT
CTGGCCGCCTCGGACGCGCTGCTGCGGGCCGTGTGCCGTCCCGGCAGCCACGTGGTGATCCCCGGCGACGCCTACGGCGG
CACGTACCGCCTGTTCGCGCGGGTGCTAGCCGAGTGGGGCGTCGAGCACACGGCGGTCGACCTGAGCGACCCGGCCGCCG
CCGTGGCCGCGATCCGGCCGGGGGCGACGGCGCTGGTGTGGTGCGAGACGCCGACCAACCCGATGCTCGCGATCGCCGAC
ATCGCCGCGCTCGCCGCCGTCGCGCACCAGGCGGGCGCGCTGCTCGTCGTCGACAACACCTTCGCCTCGCCCTACCTGTG
CCAGCCGCTGACGCTCGGCGCGGACGCGGTCGTCCACTCGACCACGAAGTACCTCGGCGGGCACAGCGACGTGGTGGGCG
GGGCGGTGGTGACCGCGTCGGCGGAGCTCGCCGAGCGGGTGCGGTTCGTACAGAACGCTGCCGGGGCCGTGCCGGGGCCG
TTCGACGCCTGGCTGGTGCTGCGCGGGATCAGGACCCTCGCGGTGCGGATGGACCGGCACTGCGCGAACGCGCGGGAGAT
CGCCGCGCTGCTCGCCGGCCACGCCGCCGTGTCGGCCGTCCACTACCCGGGGCTGGCGAGCCACCCCGGCCACGACGTCG
CTGCCAAGCAGATGCGTGACTTCGGCGGGATGGTCTCGTTCCAGGTCCAGGCCGGCGCGGAGGCCGCCCTCGCGGTGTGC
GCCGCCACCCGGCTGTTCACCCTCGCCGAGTCGCTGGGCGGGGTGGAGTCGCTGATCGAGCATCCCGCGCGGATGACGCA
CGCTTCGGTGGCGGGCTCACCGCTCGCCGTCCCCGACGACCTCGTGCGGCTCTCCGTCGGCATCGAGGCGGCCGACGACC
TGGTCGCCGACCTCGAACAGGCACTCGACTCGGCCTGA

Protein sequence :
MGDRNSGFETVAVHAGQEPDPATGAVVVPIHPASTFAQDGVGGLRAGFEYARSGNPTRAALEASLTALERGAAALAFASG
LAASDALLRAVCRPGSHVVIPGDAYGGTYRLFARVLAEWGVEHTAVDLSDPAAAVAAIRPGATALVWCETPTNPMLAIAD
IAALAAVAHQAGALLVVDNTFASPYLCQPLTLGADAVVHSTTKYLGGHSDVVGGAVVTASAELAERVRFVQNAAGAVPGP
FDAWLVLRGIRTLAVRMDRHCANAREIAALLAGHAAVSAVHYPGLASHPGHDVAAKQMRDFGGMVSFQVQAGAEAALAVC
AATRLFTLAESLGGVESLIEHPARMTHASVAGSPLAVPDDLVRLSVGIEAADDLVADLEQALDSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-55 46
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-54 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-35 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Franean1_6425 YP_001510668.1 cystathionine gamma-synthase BAC0207 Protein 9e-45 44