Gene Information

Name : guaA (Franean1_5989)
Accession : YP_001510239.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 7300224 - 7301828 bp
Length : 1605 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAACGAGTCACCTCGCGCCAGCTATGGCTCCACCGGCGCACATCCCGGTTACGATCCGGTTCTCGTGATCGACTTCGG
CGCCCAGTACGCCCAGTTGATCGCTCGGCGCGTTCGCGAGTGCCATGTGTACTCGGAGATCGTCCCGTGGGATATGCCGG
TAGCCGAGATCCTGGCCCGGCGCCCGGCCGCGCTCATCCTCTCTGGCGGGCCGAAGTCCGTCTACTCCCCGGGTGCCCCC
CGGGTCGACCCCGCGCTGTTCGCTGCCGGGGTGCCCGTCCTGGGCATCTGCTACGGCCACCAGGTGATGGCGCAGGCGCT
GGACGGCACGGTCGCCCGCACCGGCACCGCCGAGTACGGAGCCACCCGGCTGCGGGTGGACGACCCCGGGGTGCTCTTCG
ACGGCCTCCCCACCAGCCAGCAGGTCTGGATGTCGCACGGCGACTCGGTGACCGCCGCGCCCCCCGGTTTCCGGGTGACC
GCGTCGACGCCGTCCACCCCGGTCGCGGCGTTCGAGGACCCCACCCGCAGGCTCTACGGCGTGCAGTTCCACCCCGAGGT
CGTGCACAGCGAGCGCGGGATGGATGTCCTGCGGCACTTCCTGCTGGTCGGCGCGGGCTGCCGGCCGTCCTGGACGATGA
TCAATATCGTCGAGGAGGCCGTGACCGCGGTGCGGGCGCAGGTCGGCAATGGCCGGCTGATCTGCGGCCTGTCCGGCGGG
GTCGATTCGGCGGTGGCCGCCGCGCTGGTACAGCGAGCCGTCGGTGACACCCTGACCTGCGTGTTCGTCGACCACGGGCT
GTTGCGGGCGGGCGAGGCGGAACAGGTCGAACGCGACTTCGTCGCCTCCACCGGCGTCGACCTCGTCCACGTGAAGGCGG
CGGACCGCTTCGCCTCCGCGCTGGCCGGGGTGACGGATCCGGAGCAGAAGCGGAAGATCATCGGGCGGGAGTTCATCCGC
GTCTTCGAGGAGTCCGCGCGTGAGCTCGACGCCCGCGCGGAGGCGGAGGGAACGCACATCGGTTTCCTCGTCCAGGGCAC
TCTCTACCCGGACGTCATCGAGTCCGGCTCGCCCACCGCCGCCAAGATCAAGTCCCATCACAATGTCGGCGGGCTGCCGG
ACGACCTGCAGTTCGACCTGGTCGAGCCGCTGCGCACCCTGTTCAAGGACGAGGTCCGCCGGCTCGGTGAGGAGCTCGGC
CTGCCCGAGGACATCGTCTGGCGCCAGCCGTTCCCGGGCCCGGGGCTGGCCGTCCGCATCATCGGTGAGGTCACCCCCGA
GCGGCTCGAGATCGTCCGGGCCGCCGACGCGGTCGTCCGGGACGAGATCCGCCGAGCGGGGCTCGACCGGGAGATCTGGC
AGGTCTTCGCCGTGCTGCTGGCGGACGTCCGGTCGGTCGGCGTCCAGGGCGACGAGCGGACCTACGGTTTCCCGGTGGTG
CTGCGCGCGGTGACCAGCGAGGACGCGATGACCGCCGACTGGGCTCGGCTGCCCTACGACCTGCTGGAACGCATCAGCAA
CCGGGTCGTCAACGAGGTTGGGCAGGTCAACCGGGTCGTCTACGACATCACCTCGAAGCCGCCGGGCACGATCGAGTGGG
AGTAG

Protein sequence :
MNESPRASYGSTGAHPGYDPVLVIDFGAQYAQLIARRVRECHVYSEIVPWDMPVAEILARRPAALILSGGPKSVYSPGAP
RVDPALFAAGVPVLGICYGHQVMAQALDGTVARTGTAEYGATRLRVDDPGVLFDGLPTSQQVWMSHGDSVTAAPPGFRVT
ASTPSTPVAAFEDPTRRLYGVQFHPEVVHSERGMDVLRHFLLVGAGCRPSWTMINIVEEAVTAVRAQVGNGRLICGLSGG
VDSAVAAALVQRAVGDTLTCVFVDHGLLRAGEAEQVERDFVASTGVDLVHVKAADRFASALAGVTDPEQKRKIIGREFIR
VFEESARELDARAEAEGTHIGFLVQGTLYPDVIESGSPTAAKIKSHHNVGGLPDDLQFDLVEPLRTLFKDEVRRLGEELG
LPEDIVWRQPFPGPGLAVRIIGEVTPERLEIVRAADAVVRDEIRRAGLDREIWQVFAVLLADVRSVGVQGDERTYGFPVV
LRAVTSEDAMTADWARLPYDLLERISNRVVNEVGQVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-154 66
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-140 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-140 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-140 55