Gene Information

Name : Franean1_5133 (Franean1_5133)
Accession : YP_001509397.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 6148975 - 6150237 bp
Length : 1263 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGACAAGCGCTTCATCCGGGAAAATCCCGACGCCGTGAAGGAGGCTGTCCGCCTCAAGGGCGTCGACCTCGACGT
CGACGAACTGCTCCAGCTCGACCAGGAGAACCGCAAGCTGCAGTTCGAGGTCGACGAGGCCCAGGCCCGGCGCAAGTCCT
TCGCCAAGCAGTTCGCCAAGGCTGACGAGGCGCGCCGCGCCGAGCTGCGTGCCGAGCACGCCGAGTTCGACCGGCAGCTC
CGTGACCTGCGCGAGCAGCTCACCCGGACGAGCACGCGGATGTCCGAGCTGATGCTGCTCACCCCGGGCATCCCCTGGGA
GGGCGCCCCGGTCGGCCCGGACGAGTCCGCGAACGTGGTGGTCCGCACCGTGGGCACCCGCCCGGAGTTCGACTTCACCC
CGATCGACCACACCGAGCTCGCCGAGAAGCGCGGCTGGGCCGAGTTCGCCCGGGCCCGCAGGGTCGCCGGTGAGCGGGCG
TACGCCCTGGTCGGCGACATGGTCATGCTCGAGCGGGCGGTCCACTCCTACGCCCTCGACCTGCTGCGCGAGCGGGACTT
CACCCCGGTGTCGGTCCCCGCGCTGGTCAAGGAGGGCCCGCTCGTCGGCACGGGCATGCTCCCGAAGGCCCGCGAGGAGA
TCTACGAGATCCCCGCCGACGACGCGTTCCTCGCCGGGACGGCGGAGGTGGCCCTGGTCGGCCTGCATGCCGGGGAGATC
CTCGACGCCAGGCGTCTGCCGATCCGCTACGCCGGCATCTCGCCGTGCTTCCGGCGAGAGATCGGCAGCGCCAGCCGGGA
CGTCCGCGGGCTACTGCGGGTACACCAGTTCGAGAAGGTCGAGCAGTTCGTCCTGTGCGTGAACGACCCGGCGGAGTCAG
CCCGTTGGCACGCGGAGCTGCTGGCTACGGCCGAGCACATCCTGGCCGACCTGGGTCTGCACTACGAGGTCGTCGAGTGC
TCGACCGGGGACATGGGCCTGGGCAAGTTCCGGATGAACGACATCAACACGTGGTTCCCCACCCTCGACCTGTTCCGGGA
GACCCACAGCTGCTCGACGCTGCACGACTGGCAGGCCCGCCGGGCGAACCTGCGCTACCGCGACGCGGACGGCAACGTAC
GTTTCGCGCACACCCTCAACAACACCGCGGTGGCCACGCCGCGCCTGCTGGCCGCGATCCTGGAGAACTTCCAGACCGCC
GACCACCAGGTCAGGGTGCCCGAGGTGCTGCGCCCCTACCTCGGCGGCCGCGACCTGCTCTGA

Protein sequence :
MLDKRFIRENPDAVKEAVRLKGVDLDVDELLQLDQENRKLQFEVDEAQARRKSFAKQFAKADEARRAELRAEHAEFDRQL
RDLREQLTRTSTRMSELMLLTPGIPWEGAPVGPDESANVVVRTVGTRPEFDFTPIDHTELAEKRGWAEFARARRVAGERA
YALVGDMVMLERAVHSYALDLLRERDFTPVSVPALVKEGPLVGTGMLPKAREEIYEIPADDAFLAGTAEVALVGLHAGEI
LDARRLPIRYAGISPCFRREIGSASRDVRGLLRVHQFEKVEQFVLCVNDPAESARWHAELLATAEHILADLGLHYEVVEC
STGDMGLGKFRMNDINTWFPTLDLFRETHSCSTLHDWQARRANLRYRDADGNVRFAHTLNNTAVATPRLLAAILENFQTA
DHQVRVPEVLRPYLGGRDLL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-58 43