Gene Information

Name : Franean1_3767 (Franean1_3767)
Accession : YP_001508068.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Unknown
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 4466428 - 4468122 bp
Length : 1695 bp
Strand : +
Note : PFAM: N-6 DNA methylase; KEGG: cef:CE2327 putative type I restriction-modification system methylase

DNA sequence :
ATGCCCCCGCGGAGGAAGTCCGCTCAGGCCGGACCGCCCACCATGGCCCAGTTGCGCGAGACGCTGTGGAAGACGGCCGA
CAAGCTGCGCGGCTCGATGGACGCCGCCCAGTACAAGGACTTCGTCCTCGTCCTGATCTTCCTCAAGTACGTCTCGGACG
CGTTCGCCGAGCGGCGCGAGCAGATCCGGCAGGACGTGCTCGCCGACGGGATCGACGAGTCCCGGGCCGAGGAGTTCCTC
GACGACGTCGACGAGTACGCCGGGCAGGGTGTGTTCTGGGTGCCGGGGCGGGCCCGGTGGGAGCATATAGCGGCGAATGC
GAAAAGCGCCGGCATCGGGGAACTGCTGAACGCGGCGATGGACGCCGTGATGAAGACGAACCCGGCGCTCACCGGCGTCC
TCCCGCGGATCTTCAACGGCGAGGGCGTCGACCAGCACCGGCTCGGCGAGCTCGTCGACCTGCTCGGTGACGCCCGCTTC
ACCGGCCACCGGGCGACCGAGCGGCCCCCGTCCACGCCTACTGGCGAGGACGGTGCGCTTTTCGGCGAATCCGCCGCCGG
AGTTCCGACGGAAGCGGCGACCCGGCCGGCGCGGGACGTGCTGGGGGAGGTGTACGAGTATTTTCTGGAGAGGTTCGCCC
GCGCCGAGGGCAAGCGCGGCGGTGAGTTCTACACCCCGGCCAGCGTGGTGCGGTTGCTTGTCGAGGTGCTGGAACCCTAC
GAGGGCCGGGTGTACGACCCGTGCTGCGGTTCGGGCGGCATGTTCGTCCAGGCGGAGAAGTTCGTCGTCGCGCACCGAGG
GCTCACCCACTCCGGCGACATCGCCGTCTACGGCCAGGAGTCGAACGAACGGACCTGGCGGCTGGCGAAGATGAACCTCG
CCATCCACGGGATCACCGGCGACCTGAGCGCCCGGTGGGACGACACCTTCCGCAACGACCGGCATCCGGACCTGCGGGCC
GACTTCATCCTGGCGAACCCGCCCTTCAACATGTCCGACTGGGCGCGCACCGTCGACGACCAGCGCTGGCGGTACGGGAC
CCCACCGACCGGCAACGCGAACTTCGCCTGGCTGCAGCACATCATCGCCAAGCTGGGCTCCCGCGGGACCGCCGGCGTGG
TGATGGCGAACGGCTCGATGTCGTCGAAGCAGTCCGGCGAGGGTGAGATCCGCGCCGCGCTGGTCGAGGCCGACCTGGTG
GCCTGCATGATCGCGTTGCCGCCACAACTGTTCCGCACCACCCAGATCCCGGCCTGCCTGTGGTTCTTCGCGAAGGACAA
GGGCCAGCTGGGCGCCCGCTGGCTCGCCGAACGGCGCGGCGAGACGCTGTTCATCGACGCCCGCGACATGGGCACGATGA
TCGACCGCACCGAGCGCATCCTCACCGACGGTGACCTCGAGAAGATTACCGACACCTACCGTGCCTGGCGTGGCGCGAAG
TCGGCCCGCGACAAGGGCCTGGCCTACGAGAACATTCCCGGCTTCTGCTATTCGGCCTCCACCGAGGAGATCCGCACCCA
CGACCACGTCCTGACCCCGGGCCGCTACGTAGGCGCCGCCGAAGCCGACATTTCCAACGACGAGCCGATGGCCGAGAAGA
TCGAGCGTCTCGCCAAGGAACTCTTCATCCACTTCGAAGAGTCCGCTCGCCTGGAAAAGGAAGTTCGCAGCCAACTGGAG
CGCCTCGATGCCTGA

Protein sequence :
MPPRRKSAQAGPPTMAQLRETLWKTADKLRGSMDAAQYKDFVLVLIFLKYVSDAFAERREQIRQDVLADGIDESRAEEFL
DDVDEYAGQGVFWVPGRARWEHIAANAKSAGIGELLNAAMDAVMKTNPALTGVLPRIFNGEGVDQHRLGELVDLLGDARF
TGHRATERPPSTPTGEDGALFGESAAGVPTEAATRPARDVLGEVYEYFLERFARAEGKRGGEFYTPASVVRLLVEVLEPY
EGRVYDPCCGSGGMFVQAEKFVVAHRGLTHSGDIAVYGQESNERTWRLAKMNLAIHGITGDLSARWDDTFRNDRHPDLRA
DFILANPPFNMSDWARTVDDQRWRYGTPPTGNANFAWLQHIIAKLGSRGTAGVVMANGSMSSKQSGEGEIRAALVEADLV
ACMIALPPQLFRTTQIPACLWFFAKDKGQLGARWLAERRGETLFIDARDMGTMIDRTERILTDGDLEKITDTYRAWRGAK
SARDKGLAYENIPGFCYSASTEEIRTHDHVLTPGRYVGAAEADISNDEPMAEKIERLAKELFIHFEESARLEKEVRSQLE
RLDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 1e-131 50
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 2e-131 50
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 3e-132 50
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-115 45