Gene Information

Name : Franean1_3615 (Franean1_3615)
Accession : YP_001507920.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 4285362 - 4287029 bp
Length : 1668 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: fal:FRAAL4648 (2,3-dihydroxybenzoyl)adenylate synthase (2, 3-dihydroxybenzoate-AMP ligase; dihydroxybenzoic acid-activating enzyme)

DNA sequence : 
ATGCTCGCCGGGTGCACCCCGTGGCCGGAGGAGGTGGCTCGCGGCTACCGGGAGAAGGGCATCTGGCGGGGGCAGACGAT
GGGCGCGCTGCTGGCCGATCTCGCCCGCCGCCACCGCGACAGCACGGCGCTGATCCACCGCGACCGCCGGATCAGCTACA
CCGAGCTGGACGCCTGGGCCGACCGGCTGGCCGCCGGGTTCGCCGCGCACGGTGTCGCGCGCGGCGAGCGCGTGGTGGTG
CAGCTGCCGAACACGCCGGAGTTCATCGCGATCGTGTTCGGGCTGTCCCGGATCGGCGCCGTCCCGGTGTTCTCGCTGGT
CGCGCACCGGGCGACCGAGCTGACCCACCTGGTGCGGCTGTCCGGGGCCACCGGATACGTGCTGCCCGAGTCCTACCGCG
GCGTCGACCACCTCGCCCTGGCCCGGCAGCTCCGGGCGGCGACCGACACGCTGCGGACGATGTTCGTCCTCGGTGACGCC
GCCGACGGCTTCGTCGCCCTCTCAGCGGTCGAGGCCGCCGGCGACGTCGGCCGCGTCGGCGCCGGCATCGCCGCGTACGA
GGCCCCGCGGGAGCCCATGCCGCCGGCCGCCGACCCGTCCGACGTGGCGTTCTTCCTCCTCTCCGGCGGGACGACGGCGT
TGCCGAAACTGATCCCGCGCACCCACGACGACTACGTGTACCAGTCCGAGCTGGCCGCCCAGGTGTGCGAGATGTCCGCC
GATGACGTCTACCTGGCCGCGCTGCCCGTCGAGTTCAACTTCGCCTTCGGCTGCCCGGGAGTGATCGGCACGCTGCAGAC
CGGCGGGACGGCGGTGCTCGCCGACACTCCGAACCCGCTGGACTGCTTCCTGCTCGTGGAACGGCACGGCGTGACGGTGA
CCGCGATGGTCCCCTCCGTCGTGGCGCTGTGGCTGGACGCCGCCGAGTGGAACGACGCGGACCTGTCGAGCCTGCGCCTG
GTCCAGGTCGGCGGCGCCCGGATGACCCGCGAGTTCACCGCCCGCATCGGGCCTGGCCTGGGCTGCTCGCTCCAGCAGGT
GTTCGGGATGGCGGAGGGCCTGCTCTGCTTCAGCCGCCCCGACGACCCGGCCGAGGCGGTGCTGACGACGCAGGGCCGCC
CGATCTCGCCCGCTGACGAGGTGCTCATCGTCGGGCCGGACGGCGACCCGCTGCCCGGCGGCGAGATCGGCGAGCTGGTC
ACCCGTGGTCCGTACACGCTGCGCGGCTACTACCGGGTGCCGGAGTACAACGCGCGGGCGTTCACCCCGGACGGCTTCTT
CCACACCGGTGATCTCGCCCGGCTGACCCCGGCCGGCGACCTGGTGATCGAAGGCCGGATCAAGGAAATGATCATTCGGG
GCGGGGACAAGATCTCGGCCGGCGAGGTCGAGGACCACCTGCTCGCCCACCCCGGCGTCACCGCGGCGGCCGTGACCGCC
GTCCCCGACGACCTGCTCGGTGAGCGGATCTGCGCCCACCTGATCGTCGACGGGCCGGCCCCGTCGCTGGCCGAGCTCAA
GCGGGCCATGCACGCGCGCGGCGTCGCCGACTACAAGCTGCCCGACGCCGTCCGGTTCGTGACCGAGTTCCCGCTCACCC
CGCTCGGGAAGATCGACAAGTTGGCGCTGGCCGCGGCGGCCGCGTCCGAACGGAAGGCTGACGTGTGA

Protein sequence : 
MLAGCTPWPEEVARGYREKGIWRGQTMGALLADLARRHRDSTALIHRDRRISYTELDAWADRLAAGFAAHGVARGERVVV
QLPNTPEFIAIVFGLSRIGAVPVFSLVAHRATELTHLVRLSGATGYVLPESYRGVDHLALARQLRAATDTLRTMFVLGDA
ADGFVALSAVEAAGDVGRVGAGIAAYEAPREPMPPAADPSDVAFFLLSGGTTALPKLIPRTHDDYVYQSELAAQVCEMSA
DDVYLAALPVEFNFAFGCPGVIGTLQTGGTAVLADTPNPLDCFLLVERHGVTVTAMVPSVVALWLDAAEWNDADLSSLRL
VQVGGARMTREFTARIGPGLGCSLQQVFGMAEGLLCFSRPDDPAEAVLTTQGRPISPADEVLIVGPDGDPLPGGEIGELV
TRGPYTLRGYYRVPEYNARAFTPDGFFHTGDLARLTPAGDLVIEGRIKEMIIRGGDKISAGEVEDHLLAHPGVTAAAVTA
VPDDLLGERICAHLIVDGPAPSLAELKRAMHARGVADYKLPDAVRFVTEFPLTPLGKIDKLALAAAAASERKADV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-105 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 7e-105 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-103 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-103 44
ybtE CAA21394.1 - Virulence HPI Protein 2e-103 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-103 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-103 44
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-103 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-103 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Franean1_3615 YP_001507920.1 AMP-dependent synthetase and ligase VFG0168 Protein 5e-111 47
Franean1_3615 YP_001507920.1 AMP-dependent synthetase and ligase VFG1817 Protein 3e-105 46
Franean1_3615 YP_001507920.1 AMP-dependent synthetase and ligase VFG0932 Protein 1e-98 42