Gene Information

Name : Franean1_3057 (Franean1_3057)
Accession : YP_001507375.1
Strain : Frankia sp. EAN1.pec
Genome accession: NC_009921
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 3595869 - 3597494 bp
Length : 1626 bp
Strand : -
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro04793 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase

DNA sequence : 
ATGAGCATCCAACCGCTGACCCTTGACGGCGTCGTACCCTATCCGCCAAAGTCCGTGGCCCAGTACCTCACAAAGGGATA
CTGGCACGATCAGACGCTTCCGGAGTTGCTTTTTGCCGCGGCGGAACGCTATCCAGACAAGCTCGCGGTCATCGACCGCG
ACACCCGGCTGAGCTATAGGCAACTCACGGATGAAGTCCTGCGTCTCGCGGCCGGTCTGCAGGATCTGGGGCTGGGCCGT
GGCGACCGAGTGGTCGTGCATCTGCCCAATACCTACGAGTACATCGCGTTCGTCTTCGCCCTGTGGGAGCTCGGCGTGAT
TCCCGTGGTCGCGCCCATCGCGCACCGTCGCGCGGAGATCGAACACTTCATCGAGATTGCCGAGGCGCGTACCTACATCA
CCGTCGCATCGGACAGCGGCACCGATCTCGCTGCGTTGGCTGCCGACCTGAAGGGTCGTTGGGCCCATCTGGAGCACACA
GTGATCCTCGATCGCGGCGGCGGCGGCGCCGAGTACGACGCGCTGCTTTCGAAAGGATCGCTCGAGCACGTGCGGCGATG
CAGCCCGCAGGACGTCGCGCTGCTGCAGATGTCGGGCGGCACTACGGGCGTTCCGAAGCTGATGCCGCATACTCATCACA
CGTACGGTTATGCGTTGCGCAGAAGCGTCGGGGAACGGGGCATCACCGAGCGGACGGTGCATCTGCTGGTCATGCCGATC
TGTCACAGTATGTCGACGCGTTCGCCCGGCTTCCTCGGCGCGTTCAGCGTGGGCGCAACGATCGTGATCGCGCCGAACGG
CAGCCCCGATGCGGCGTTCCCGCTGATCGAGAAGCACCGCGCGAACCGCGTGACGTTGGTGCCCCCGATCCTGCTGGCCT
GGCTGAACTCCTCGCTGCGCGACGCCTACGATCTCTCCAGCATGCAGGTGATCATGTGCGGGGGTGCGAAGCTGAGCGAG
GAGGTGGCGCGGCGGGTCGAGCCGGAGCTCGGCATGGAGCTGTCTCAGAGCTTCGGGATGGGCGAAGGCCTGGTCGTCAG
CAACCCTCCGGACGTCGATCGGGAGACCAGCGTGCGATACCAGGGCCGGCCGGCCTCGGAGGCCGACGAGATCCGGGTCA
TAGACGACGAGGGAAACGACGTGCCGCCCGGGGCGCCCGGTCACCTGCTGACGCGGGGGCCGTCGGTAATCCGCGGCTAC
TATCGCAACCCCGAGCAGAATGCCCTGGCGTTCACCAGCGATGGCTTCTACCGCACCGGTGACATAGTCGAGCGGGACGA
GCGTGGGTTCATGAGGGTCGTGGGCCGGTCGAAGGACCAGATCAACCGTGGCGGCGAGAAGATCGCGCCGGAGGAGCTGG
AGAACGCGTTCCTCGCCCACGGCGGCGTGCACAACGCCTCCGTGATCGGCATCGATGACGAGGTGCTCGGCGAGCGCATC
AAGGCGTACCTGATCCCTCGGTCGCCGGAGGACGTGGCCGATCTCACCTTGAGCAAGCTGCGTCGGTTCCTGCAGGAGTG
GGGCCTCGCGACATTCAAGCTTCCCGATTTCGTGGAGGTGGTCGACAAGTTCCCGTACACCGCGGTCGGCAAGGTCAGCA
AGCGACTGCAGCGCGAGCAGAACTAG

Protein sequence : 
MSIQPLTLDGVVPYPPKSVAQYLTKGYWHDQTLPELLFAAAERYPDKLAVIDRDTRLSYRQLTDEVLRLAAGLQDLGLGR
GDRVVVHLPNTYEYIAFVFALWELGVIPVVAPIAHRRAEIEHFIEIAEARTYITVASDSGTDLAALAADLKGRWAHLEHT
VILDRGGGGAEYDALLSKGSLEHVRRCSPQDVALLQMSGGTTGVPKLMPHTHHTYGYALRRSVGERGITERTVHLLVMPI
CHSMSTRSPGFLGAFSVGATIVIAPNGSPDAAFPLIEKHRANRVTLVPPILLAWLNSSLRDAYDLSSMQVIMCGGAKLSE
EVARRVEPELGMELSQSFGMGEGLVVSNPPDVDRETSVRYQGRPASEADEIRVIDDEGNDVPPGAPGHLLTRGPSVIRGY
YRNPEQNALAFTSDGFYRTGDIVERDERGFMRVVGRSKDQINRGGEKIAPEELENAFLAHGGVHNASVIGIDDEVLGERI
KAYLIPRSPEDVADLTLSKLRRFLQEWGLATFKLPDFVEVVDKFPYTAVGKVSKRLQREQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-75 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-74 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-74 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-74 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-74 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-74 42
ybtE CAA21394.1 - Virulence HPI Protein 1e-74 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-72 41
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Franean1_3057 YP_001507375.1 AMP-dependent synthetase and ligase VFG0168 Protein 7e-88 44
Franean1_3057 YP_001507375.1 AMP-dependent synthetase and ligase VFG0932 Protein 2e-75 42