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Name : ddl (Franean1_1130) Accession : YP_001505490.1 Strain : Frankia sp. EAN1.pec Genome accession: NC_009921 Putative virulence/resistance : Resistance Product : D-alanyl-alanine synthetase A Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : 6.3.2.4 Position : 1350882 - 1351985 bp Length : 1104 bp Strand : - Note : D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli DNA sequence : ATGGGAGCCTCCACGCGCAGGGTTCGGCTCGTCCTTCTGTTCGGCGGCCGTAGCACGGAGCATTCGATCTCGTGCGTGTC CGCCGGCGGGGTGCTGCGGGCGCTCGACCGGTCCCGTTACGACGTGATCCCGGTCGGCATCGACACCGAGGGCCGCTGGG CGGTGCTGCCCGACGACAGTCCGGCGCTCGCCCCGGTGGGCACGGATCTCCCCATCGTCGACGCGTCGGCCGGCCTGGCC GTCACGCTGCCCCCGAGCCCGTCCGCGGCGCCGGTGGTGGTGCACGACCCGTCCGCGGCGCTGCGCGACCTGGGCCCCGT TGACGTGGTCTTCCCGTTGCTGCACGGGCCGTTCGGCGAGGACGGCACGATCCAGGGCCTGCTCGAGATGGCCGGGCTGC CCTACGTGGGCTCCGGAGTGTTCGCCAGCGCCGCGGCCATGGACAAACAGCACATGAAGAGCATGCTCGCCGCAGCCGGC CTGCCCGTCGGCCCCTACGCCGTCCTGCGGCCCGGCCAGGCGCTGTCGGAGCCCGACCGCGAGCGGCTCGGGCTCCCCGT CTTCGTCAAGCCCGCGCGCGGCGGCTCCAGCATCGGCATCAGCCGGGTGGACGCCTGGGCCGACCTCGACACGGCGCTGA AGACAGCCCGGGCCAGCGACCCGAAGACACTCGTCGAGGCGGCGGTCGTCGGCCGCGAGATCGAGTGCGGCGTCCTCGAC AGCCTCGACGGCTCCGGCCCACAGGCGAGCGTGCCGGCCGAGGTCACCATCACCTCGTCGGCCGGCTTCTACGATTTCGA GGCGAAGTACCTCTCGGACGGAGCCGTCTTCGACGTGCCCGCGCGCCTGCCGGGTGAGCTGACCGAGCGGGTCCGCGCGG CCGCGGTCGCCGCGTTCGAGGCGTTGGACTGCGCCGGGCTGGCGCGGGTCGACATGTTCGTCACGCCGTCGGGCGAGATC GTCCTCAACGAGGTCAACACGATGCCCGGGTTCACCCCGATGTCGATGTACCCACGGATGTGGGCCGCCTCCGGGATCGA CTACGCGGCCCTGGTGGACCGCCTCGTCCAGCTCGCCCTGCGCGACGGCGCGGGCCTTCGCTGA Protein sequence : MGASTRRVRLVLLFGGRSTEHSISCVSAGGVLRALDRSRYDVIPVGIDTEGRWAVLPDDSPALAPVGTDLPIVDASAGLA VTLPPSPSAAPVVVHDPSAALRDLGPVDVVFPLLHGPFGEDGTIQGLLEMAGLPYVGSGVFASAAAMDKQHMKSMLAAAG LPVGPYAVLRPGQALSEPDRERLGLPVFVKPARGGSSIGISRVDAWADLDTALKTARASDPKTLVEAAVVGREIECGVLD SLDGSGPQASVPAEVTITSSAGFYDFEAKYLSDGAVFDVPARLPGELTERVRAAAVAAFEALDCAGLARVDMFVTPSGEI VLNEVNTMPGFTPMSMYPRMWAASGIDYAALVDRLVQLALRDGAGLR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 8e-40 | 44 |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 1e-37 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ddl | YP_001505490.1 | D-alanyl-alanine synthetase A | U00456.gene.p01 | Protein | 5e-38 | 44 |
| ddl | YP_001505490.1 | D-alanyl-alanine synthetase A | U35369.1.gene6.p01 | Protein | 5e-38 | 44 |
| ddl | YP_001505490.1 | D-alanyl-alanine synthetase A | AE016830.1.gene2250. | Protein | 5e-38 | 44 |
| ddl | YP_001505490.1 | D-alanyl-alanine synthetase A | AY145441.gene.p01 | Protein | 5e-38 | 43 |
| ddl | YP_001505490.1 | D-alanyl-alanine synthetase A | AF310956.2.orf5.gene | Protein | 3e-38 | 43 |
