Gene Information

Name : A1C_04135 (A1C_04135)
Accession : YP_001493608.1
Strain : Rickettsia akari Hartford
Genome accession: NC_009881
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 746259 - 747638 bp
Length : 1380 bp
Strand : -
Note : Catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGCAAGAATTTGATTTAGTGGTAATAGGTAGCGGTCCGGCCGGTTATACAGGTAGTATTAGAGCTGCTCAGCTTGGTAT
GAAAGTAGTGTGTGTTGAGAAAAATGATACTCTCGGTGGCACTTGTTTAAATATAGGATGCATACCGTCGAAAGCTTTAC
TTAATTCCTCTGAAAAATATGAAGAAGCTTTAAAGCATTTTGAGAGTATAGGTATTACTGCGGATGTAAAATTAGACTTA
CAAAAAATGATAGCTAATAAAGATAAAGTAGTTTCTGACCTTACAAAAGGGATAGAAAGCTTATTTGCTAAGAATAAGAT
TACTAGGATAAAGGGTGAAGCTAAAATTATCGCGAGCAACATTGTGGAAGTAAATAATGAGCAAATTAAAGCCAAAAATA
TCCTAATTACTACGGGTTCCAGCGTCATAGAAATACCAAATATCAAAATAGATGAAGAGTTTATAGTTTCATCTACCGGA
GCTTTAAAGCTTTCTAAAGTACCTGAGACCTTAATAGTTGTCGGGGGAGGATATATAGGCTTAGAACTCGGCTCAGTTTG
GCGTCGTTTAGGTGCTAAAGTAACGGTTATTGAGTATGCACCGAGCATTGTGCCTATGCTTGATAAAGAAATTGCTACGC
AGTTTATGAAGCTACAGCAAAAACAAGGTATAGAGTTTAAACTAAATACTAGAGTGTTGTCTGCTGAAGTAAAGTCAGGA
AAAGTAAATCTGACAATAGAGGAGGGCGGTAAGAGTGCGGTAGTAACTAGCGATGTGATATTAATGGCAGTAGGTAGAAA
AGCCTACACGCAAAATCTAGGGCTTGAGTCTGTCGGCATTATTACAGATAAGCAAGGTAGAATTGAGATTAATGACCGGT
TCCAAACAGCAATTTCAAATATTTATGCAGTCGGGGATGTGGTAAAAGGAGCTATGCTTGCTCATAAAGCCGAGGAAGAG
GCTGTAGCTGCCGTGGAAATTATGGCAGGGCAGGCAGGACATGTTAACTATAATCTAATTCCAAGCGTAATATATACTTA
TCCTGAAGTAGCAAGCGTCGGTGAAACGGAAGAACAGTTAAAAGCAAAAGGCATTAATTATAAAGTAGGTAAGTTTCCGT
TTTTAGCAAATAGTAGAGCAAGAGCAATCGGTAGTACGGAAGGGCTTGTTAAGATCCTTGCCGATAGTAAAACCGATAGG
GTTTTAGGAGCTCATATTATAGGAGCCAATGCAGGTACACTCATTGCCGAGCTTACGGCTTATATGGAATTCGGAGCAGC
TTCAGAAGATATAGCAAGAACCTGCCACGCCCACCCGACTTTAAGCGAGGCTATAAAAGAAGCAGCTCTTAGTGTGGATA
AGAGGAGTATCAATATGTGA

Protein sequence :
MQEFDLVVIGSGPAGYTGSIRAAQLGMKVVCVEKNDTLGGTCLNIGCIPSKALLNSSEKYEEALKHFESIGITADVKLDL
QKMIANKDKVVSDLTKGIESLFAKNKITRIKGEAKIIASNIVEVNNEQIKAKNILITTGSSVIEIPNIKIDEEFIVSSTG
ALKLSKVPETLIVVGGGYIGLELGSVWRRLGAKVTVIEYAPSIVPMLDKEIATQFMKLQQKQGIEFKLNTRVLSAEVKSG
KVNLTIEEGGKSAVVTSDVILMAVGRKAYTQNLGLESVGIITDKQGRIEINDRFQTAISNIYAVGDVVKGAMLAHKAEEE
AVAAVEIMAGQAGHVNYNLIPSVIYTYPEVASVGETEEQLKAKGINYKVGKFPFLANSRARAIGSTEGLVKILADSKTDR
VLGAHIIGANAGTLIAELTAYMEFGAASEDIARTCHAHPTLSEAIKEAALSVDKRSINM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 2e-73 41